Results 211 to 220 of about 640,321 (318)

Identification and Verification of Anoikis-related Genes in Epilepsy Through Bioinformatics Analysis. [PDF]

Brain Behav
Zeng H, Yuan Y, Tan T, Zhou W, Zhou X, Chen X.   +5 more
europepmc   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

RNA sequencing and bioinformatics analysis of blood from patients with cortical cataracts. [PDF]

BMC Ophthalmol
Li Q, Zhu L.
europepmc   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

Bioinformatic Analysis of Cardiac Transcription Networks

, 2011
A panel of key transcription factors are the main drivers of the cardiac developmental process and are essential for normal cardiac function. However, limited insights have been generated at a systemslevel about how these factors modulate the overall transcription network, how they act in a combinatorial manner and moreover how they interplay with ...
openaire   +2 more sources

Bioinformatics analysis and clinical validation identify <i>FBXW9</i> as a biomarker in bladder urothelial carcinoma. [PDF]

Transl Androl Urol
Li D, Wu W, Chen Y, Liang Z, Zhang Q, Yuan C, Liao S, Liao Y, Si W, Yu X, Huang M.   +10 more
europepmc   +1 more source

Decoding IGLL5 Mutation‐Mediated BCR Signaling: A Novel Mechanism of CD8+ T Cell Exhaustion and Ocular MALT Lymphoma Progression

Advanced Science, EarlyView.
OAML harbors recurrent IGLL5 mutations that reinforce CD79A/CD79B‐associated BCR signaling. Mechanistic analysis of the S47G and A54G variants reveals induction of CXCL10/CXCL11, enhanced CD8+ T‐cell recruitment, and exhaustion‐associated dysfunction, supporting an immune‐tolerant niche.
Andi Zhao, Haoyu Wei, Chenyu Zhou, Xinping Sun, Shuyan Da, Haiyu Liu, Zijin Wang, Hui Zhu, Shiya Shen, Qing Shao, Qi Gong, Hu Liu, Xuejuan Chen   +12 more
wiley   +1 more source

Bioinformatics analysis of TRPV1 expression and its role in hepatocellular carcinoma prognosis. [PDF]

Discov Oncol
Kashyap VK, Sharma BP, Singh HN, Kumar S, Verma D, Parashar D, Yallapu MM, Cobos E, Chauhan SC.   +8 more
europepmc   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Bioinformatics analysis in obstetrics and gynaecology

Journal of Obstetrics and Gynaecology
openaire   +3 more sources