Results 1 to 10 of about 3,467,432 (197)
RadiologyLiquid biopsy helps detect cells and cell-derived metabolites, proteins, nucleic acids, and vesicles that are shed into body fluids by tumors. This diagnostic test requires only approximately 10 mL of blood or urine.
Marius E. Mayerhoefer +3 more
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Editorial: Liquid biopsy biomarkers for cancer detection, treatment monitoring, and clinical outcome prediction [PDF]
Frontiers in Cell and Developmental BiologyGraphical AbstractInfographic illustrating liquid biopsy as a dynamic window into cancer, highlighting multiple biomarker sources such as tumor cells, DNA, RNA, extracellular vesicles, immune and stromal cells, and platelets.
Keerthi Kurma +7 more
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Biology, 2021 Next-generation sequencing (NGS) has enabled a deeper knowledge of the molecular landscape in non-small cell lung cancer (NSCLC), identifying a growing number of targetable molecular alterations in key genes.
Roberto Serna-Blasco +6 more
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, 2023 New ways of looking at tumor genetics and dynamics have been developed: the Liquid Biopsy (LB), which has been incorporated into clinical practice as a noninvasive analysis of circulating material derived from tumors, which represents an innovative tool in precision oncology and overcomes the current limitations associated with tissue biopsies.
Valeria Denninghoff, Maria Jose Serrano
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Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway
Journal of Experimental & Clinical Cancer Research, 2022 Background Mitochondrial dynamics homeostasis is important for cell metabolism, growth, proliferation, and immune responses. The critical GTPase for mitochondrial fission, Drp1 is frequently upregulated in many cancers and is closely implicated in ...
Yujia Li +14 more
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Liquid biopsy and glioblastoma
Exploration of Targeted Anti-tumor Therapy, 2022 Glioblastoma is the most common and malignant primary brain tumor. Despite a century of research efforts, the survival of patients has not significantly improved. Currently, diagnosis is based on neuroimaging techniques followed by histopathological and molecular analysis of resected or biopsied tissue.
Robert Eibl, Markus Schneemann
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Cancer as an infective disease: the role of EVs in tumorigenesis
Molecular Oncology, 2023 Cancer is conventionally considered an evolutionary disease where tumor cells adapt to the environment and evolve eventually leading to the formation of metastasis through the seeding and growth of metastasis‐initiating cells in distant organs.
Lucia Robado de Lope +4 more
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Ivermectin induces apoptosis of esophageal squamous cell carcinoma via mitochondrial pathway
BMC Cancer, 2021 Background Esophageal squamous cell carcinoma (ESCC) is the most predominant primary malignant tumor among worldwide, especially in China. To date, the successful treatment remains a mainly clinical challenge, it is imperative to develop successful ...
Nana Xu +13 more
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Frontiers in Oncology, 2022 Cancer cells release nucleic acids, freely or associated with other structures such as vesicles into body fluids, including blood. Among these nucleic acids, circulating tumor DNA (ctDNA) has emerged as a minimally invasive biomarker for tumor molecular ...
Estela Sánchez-Herrero +8 more
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Cancers, 2022 Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Despite recent advances in therapy modalities, the overall survival of GBM patients remains poor. GBM diagnosis relies on neuroimaging techniques. However, confirmation via histopathological and molecular analysis is necessary.
Lorian Ronvaux +7 more
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