Results 21 to 30 of about 1,653,509 (288)

Liquid Biopsy in Glioblastoma

Cancers, 2022
Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Despite recent advances in therapy modalities, the overall survival of GBM patients remains poor. GBM diagnosis relies on neuroimaging techniques. However, confirmation via histopathological and molecular analysis is necessary.
Lorian Ronvaux, Matteo Riva, An Coosemans, Marielle Herzog, Guillaume Rommelaere, Nathalie Donis, Lionel D’Hondt, Jonathan Douxfils   +7 more
openaire   +3 more sources

Genomic landscape and survival analysis of ctDNA “neo-RAS wild-type” patients with originally RAS mutant metastatic colorectal cancer

Frontiers in Oncology, 2023
BackgroundThe term “neo-RAS wild-type” refers to the switch to RAS wild-type disease in plasma circulating tumor DNA (ctDNA) from originally RAS mutant colorectal cancers.
Chiara Nicolazzo, Valentina Magri, Luca Marino, Francesca Belardinilli, Federica Di Nicolantonio, Gianluigi De Renzi, Salvatore Caponnetto, Michela De Meo, Giuseppe Giannini, Daniele Santini, Enrico Cortesi, Paola Gazzaniga   +11 more
doaj   +1 more source

AIFM2 promotes hepatocellular carcinoma metastasis by enhancing mitochondrial biogenesis through activation of SIRT1/PGC-1α signaling

Oncogenesis, 2023
AIFM2 is a crucial NADH oxidase involved in the regulation of cytosolic NAD+. However, the role of AIFM2 in the progression of human cancers remains largely unexplored.
Sanxing Guo, Fengying Li, Yixuan Liang, Yufei Zheng, Yingyi Mo, Deyao Zhao, Zhixiong Jiang, Mengmeng Cui, Lixia Qi, Jiaxing Chen, Lixin Wan, Guoyong Chen, Sidong Wei, Qi Yang, Junqi Liu   +14 more
doaj   +1 more source

Liquid biopsy [PDF]

Nature Biotechnology, 2021
Amit Kumar Jain, Guruprasad Bhat, Vineet Govinda Gupta, Hari Goyal   +3 more
  +7 more sources

Liquid biopsies

Genes, Chromosomes and Cancer, 2019
AbstractLiquid biopsy is based on minimally invasive blood tests and has a high potential to significantly change the therapeutic strategy in cancer patients, providing an extremely powerful and reliable noninvasive clinical tool for the individual molecular profiling of patients in real time.
Evi Lianidou, Klaus Pantel
openaire   +3 more sources

Epidermal Growth Factor Receptor T790M Mutation Testing in Non-Small Cell Lung Cancer: An International Collaborative Study to Assess Molecular EGFR T790M Testing in Liquid Biopsy

, 2023
Background: The detection of the EGFR T790M (T790M) mutation in non-small cell lung cancer (NSCLC) patients who progressed under treatment with first- or second-generation EGFR-tyrosine kinase inhibitors (TKIs) is important to offer a subsequent therapy ...
Viktor Sebek, Herwig Zach, on behalf of the Liquid Biopsy Collaborative Study Group on behalf of the Liquid Biopsy Collaborative Study Group, Verena Kainz, Martin Filipits   +4 more
core   +1 more source

3D-printed device for DNA fragmentation prior liquid biopsy testing [PDF]

, 2023
Direct detection of DNA in complex biological samples relates to several problems regarding the selectivity and sensitivity of analyses. Therefore, DNA pre-extraction from biofluids is an emerging tool in biologically related fields.
Marek, Minárik, František, Foret, Helena, Hrušková, Roman, Řemínek   +3 more
core   +1 more source

Overview of liquid biopsy

, 2022
New studies are mainly focused on the new, minimally invasive biomarkers presenting in body fluids as the real-time representative of tumors, entitled “liquid biopsy.” Liquid biopsy contains tumor-derived cells, nucleic acids (DNA, RNA), and tumor ...
Yarandi V. A., Aghamir S. M. K., Khatami F., Rezaeian A., Fiorentino M.   +4 more
core   +1 more source

Liquid Biopsy

, 2023
تم تطوير طرق جديدة للنظر في جينات الورم وديناميكياته: الخزعة السائلة (LB)، والتي تم دمجها في الممارسة السريرية كتحليل غير جراحي للمواد المتداولة المستمدة من الأورام، والتي تمثل أداة مبتكرة في علم الأورام الدقيق وتتغلب على القيود الحالية المرتبطة بخزعات الأنسجة. LB هي أداة جديدة ذات قيمة كبيرة، وتشكل علامة تشخيصية وتنبؤية وتنبؤية.
Alejandra Avagnina, María José Serrano
  +5 more sources

Liquid biopsy.

Journal of biological regulators and homeostatic agents, 2019
During the early formation and growth of primary tumor (e.g., breast, colon, or prostate cancer), cells are shed from the primary tumor and then circulate through the bloodstream. Many of the major recent advances in targeted therapies have relied on the acquisition of tumor tissue via biopsy before initiation of therapy or after the onset of ...
Candotto, V, Pezzetti, F, Scarano, A, Agazzi, A, Spadari, F, Palmieri, A   +5 more
  +9 more sources