Results 21 to 30 of about 5,116,830 (334)
Cancer in a Drop: Liquid biopsy insights from AACR 2026 [PDF]
Pasquale Pisapia +3 more
doaj +2 more sources
Background: The detection of the EGFR T790M (T790M) mutation in non-small cell lung cancer (NSCLC) patients who progressed under treatment with first- or second-generation EGFR-tyrosine kinase inhibitors (TKIs) is important to offer a subsequent therapy ...
Viktor Sebek +4 more
core +1 more source
During the early formation and growth of primary tumor (e.g., breast, colon, or prostate cancer), cells are shed from the primary tumor and then circulate through the bloodstream. Many of the major recent advances in targeted therapies have relied on the acquisition of tumor tissue via biopsy before initiation of therapy or after the onset of ...
Candotto, V +5 more
+9 more sources
Abstract Liquid biopsy is based on minimally invasive blood tests and has a high potential to significantly change the therapeutic strategy in cancer patients, providing an extremely powerful and reliable noninvasive clinical tool for the individual molecular profiling of patients in real time.
Evi Lianidou, Klaus Pantel
openaire +3 more sources
Despite impressive and durable responses, nonsmall cell lung cancer (NSCLC) patients treated with anaplastic lymphoma kinase (ALK) inhibitors (ALK‐Is) ultimately progress due to development of resistance.
Estela Sánchez‐Herrero +17 more
doaj +1 more source
The high incidence and mortality of lung cancer make early detection of lung cancer particularly important. At present, the diagnosis of lung cancer mainly depends on diagnostic imaging and tissue biopsy. However, current diagnostics are not satisfactory
Lanxiang Huang +11 more
doaj +1 more source
Liquid biopsy: current technology and clinical applications
Liquid biopsies are increasingly used for cancer molecular profiling that enables a precision oncology approach. Circulating extracellular nucleic acids (cell-free DNA; cfDNA), circulating tumor DNA (ctDNA), and circulating tumor cells (CTCs) can be ...
M. Nikanjam, S. Kato, R. Kurzrock
semanticscholar +1 more source
3D-printed device for DNA fragmentation prior liquid biopsy testing [PDF]
Direct detection of DNA in complex biological samples relates to several problems regarding the selectivity and sensitivity of analyses. Therefore, DNA pre-extraction from biofluids is an emerging tool in biologically related fields.
Marek, Minárik +3 more
core +1 more source
The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring [PDF]
The emerging field of liquid biopsy stands at the forefront of novel diagnostic strategies for cancer and other diseases. Liquid biopsy allows minimally invasive molecular characterization of cancers for diagnosis, patient stratification to therapy, and ...
Ekanayake, Emil +112 more
core +3 more sources

