Results 11 to 20 of about 1,653,509 (288)

Liquid Biopsy and NSCLC [PDF]

Lung Cancer Management, 2016
In the era of high-throughput molecular screening and personalized medicine, difficulty in determining whether cancer mutations are truly 'actionable' remains a gray zone in NSCLC. The most important prerequisite to perform such investigations is the tumor tissue retrieval via biopsy at diagnosis and after occurrence of resistance.
Trombetta, D., Sparaneo, A., Fabrizio, F. P., Muscarella, L. A.   +3 more
openaire   +4 more sources

Harmonizing definitions in liquid biopsy: A terminology framework by the international society of liquid biopsy. [PDF]

J Liq Biopsy
The rapid expansion of liquid biopsy (LB) throughout the cancer care continuum is evidenced by the striking increase in annual publications, rising from approximately 100 per year in the early 2000s to more than 2200 in recent years.
Jantus-Lewintre E, Calabuig-Fariñas S, Gandara D, Raez L, Leighl NB, Fusco N, Khorshid O, Mayo de Las Casas C, Reduzzi C, Urum Y, Aggarwal C, Serrano MJ, Rolfo C, Malapelle U.   +13 more
europepmc   +2 more sources

Electrochemical liquid biopsy across cancer care pathway. [PDF]

J Liq Biopsy
Liquid biopsy has emerged as a powerful approach for tracking tumor dynamics through circulating biomarkers such as cell-free tumor DNA (ctDNA), circulating tumor cells (CTCs), extracellular vesicles (EVs), microRNAs (miRNAs) and soluble proteins. Unlike
Singh S, Raucci A, Miglione A, Kalligosfyri PM, Misso G, Caraglia M, Cocco S, De Laurentiis M, Giordano A, Cinti S.   +9 more
europepmc   +2 more sources

R-Score: A New Parameter to Assess the Quality of Variants’ Calls Assessed by NGS Using Liquid Biopsies

Biology, 2021
Next-generation sequencing (NGS) has enabled a deeper knowledge of the molecular landscape in non-small cell lung cancer (NSCLC), identifying a growing number of targetable molecular alterations in key genes.
Roberto Serna-Blasco, Estela Sánchez-Herrero, María Berrocal Renedo, Silvia Calabuig-Fariñas, Miguel Ángel Molina-Vila, Mariano Provencio, Atocha Romero   +6 more
doaj   +1 more source

Liquid Biopsies [PDF]

Medizinische Genetik, 2016
Zusammenfassung „Liquid Biopsy“ bezieht sich in der Onkologie auf die Untersuchung von zirkulierenden Tumorzellen (engl.: circulating tumor cells [CTCs]) oder zirkulierender Tumor-DNA (engl.: circulating tumor DNA [ctDNA]), um nicht invasiv aus dem peripheren Blut Charakteristika über das Tumorgenom von Krebspatienten zu erfassen.
Michael R. Speicher, Armin Gerger, Gerald Hoefler   +2 more
  +5 more sources

Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway

Journal of Experimental & Clinical Cancer Research, 2022
Background Mitochondrial dynamics homeostasis is important for cell metabolism, growth, proliferation, and immune responses. The critical GTPase for mitochondrial fission, Drp1 is frequently upregulated in many cancers and is closely implicated in ...
Yujia Li, Hui Chen, Qi Yang, Lixin Wan, Jing Zhao, Yuanyuan Wu, Jiaxin Wang, Yating Yang, Menglan Niu, Hongliang Liu, Junqi Liu, Hushan Yang, Shaogui Wan, Yanming Wang, Dengke Bao   +14 more
doaj   +1 more source

Liquid biopsy and glioblastoma

Exploration of Targeted Anti-tumor Therapy, 2022
Glioblastoma is the most common and malignant primary brain tumor. Despite a century of research efforts, the survival of patients has not significantly improved. Currently, diagnosis is based on neuroimaging techniques followed by histopathological and molecular analysis of resected or biopsied tissue.
Robert Eibl, Markus Schneemann
openaire   +3 more sources

Cancer as an infective disease: the role of EVs in tumorigenesis

Molecular Oncology, 2023
Cancer is conventionally considered an evolutionary disease where tumor cells adapt to the environment and evolve eventually leading to the formation of metastasis through the seeding and growth of metastasis‐initiating cells in distant organs.
Lucia Robado de Lope, Estela Sánchez‐Herrero, Roberto Serna‐Blasco, Mariano Provencio, Atocha Romero   +4 more
doaj   +1 more source

Ivermectin induces apoptosis of esophageal squamous cell carcinoma via mitochondrial pathway

BMC Cancer, 2021
Background Esophageal squamous cell carcinoma (ESCC) is the most predominant primary malignant tumor among worldwide, especially in China. To date, the successful treatment remains a mainly clinical challenge, it is imperative to develop successful ...
Nana Xu, Mengmeng Lu, Jiaxin Wang, Yujia Li, Xiaotian Yang, Xiajie Wei, Jiaoyang Si, Jingru Han, Xiaojuan Yao, Juanmei Zhang, Junqi Liu, Yanming Li, Hushan Yang, Dengke Bao   +13 more
doaj   +1 more source

Circulating Tumor DNA as a Cancer Biomarker: An Overview of Biological Features and Factors That may Impact on ctDNA Analysis

Frontiers in Oncology, 2022
Cancer cells release nucleic acids, freely or associated with other structures such as vesicles into body fluids, including blood. Among these nucleic acids, circulating tumor DNA (ctDNA) has emerged as a minimally invasive biomarker for tumor molecular ...
Estela Sánchez-Herrero, Estela Sánchez-Herrero, Roberto Serna-Blasco, Lucia Robado de Lope, Víctor González-Rumayor, Atocha Romero, Atocha Romero, Mariano Provencio, Mariano Provencio   +8 more
doaj   +1 more source