Results 11 to 20 of about 126,740 (294)

Epidermal Growth Factor Receptor T790M Mutation Testing in Non-Small Cell Lung Cancer: An International Collaborative Study to Assess Molecular EGFR T790M Testing in Liquid Biopsy [PDF]

, 2023
Background: The detection of the EGFR T790M (T790M) mutation in non-small cell lung cancer (NSCLC) patients who progressed under treatment with first- or second-generation EGFR-tyrosine kinase inhibitors (TKIs) is important to offer a subsequent therapy ...
Viktor Sebek, Herwig Zach, on behalf of the Liquid Biopsy Collaborative Study Group on behalf of the Liquid Biopsy Collaborative Study Group, Verena Kainz, Martin Filipits   +4 more
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Overview of liquid biopsy [PDF]

, 2022
New studies are mainly focused on the new, minimally invasive biomarkers presenting in body fluids as the real-time representative of tumors, entitled “liquid biopsy.” Liquid biopsy contains tumor-derived cells, nucleic acids (DNA, RNA), and tumor ...
Yarandi V. A., Aghamir S. M. K., Khatami F., Rezaeian A., Fiorentino M.   +4 more
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Liquid biopsy and glioblastoma

Exploration of Targeted Anti-tumor Therapy, 2022
Glioblastoma is the most common and malignant primary brain tumor. Despite a century of research efforts, the survival of patients has not significantly improved. Currently, diagnosis is based on neuroimaging techniques followed by histopathological and molecular analysis of resected or biopsied tissue.
Robert Eibl, Markus Schneemann
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Liquid Biopsy

, 2023
New ways of looking at tumor genetics and dynamics have been developed: the Liquid Biopsy (LB), which has been incorporated into clinical practice as a noninvasive analysis of circulating material derived from tumors, which represents an innovative tool in precision oncology and overcomes the current limitations associated with tissue biopsies.
Valeria Denninghoff, Maria Jose Serrano
  +5 more sources

Liquid Biopsy in Glioblastoma

Cancers, 2022
Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Despite recent advances in therapy modalities, the overall survival of GBM patients remains poor. GBM diagnosis relies on neuroimaging techniques. However, confirmation via histopathological and molecular analysis is necessary.
Lorian Ronvaux, Matteo Riva, An Coosemans, Marielle Herzog, Guillaume Rommelaere, Nathalie Donis, Lionel D’Hondt, Jonathan Douxfils   +7 more
openaire   +3 more sources

Liquid Biopsy and NSCLC [PDF]

Lung Cancer Management, 2016
In the era of high-throughput molecular screening and personalized medicine, difficulty in determining whether cancer mutations are truly 'actionable' remains a gray zone in NSCLC. The most important prerequisite to perform such investigations is the tumor tissue retrieval via biopsy at diagnosis and after occurrence of resistance.
Trombetta, D., Sparaneo, A., Fabrizio, F. P., Muscarella, L. A.   +3 more
openaire   +2 more sources

3D-printed device for DNA fragmentation prior liquid biopsy testing [PDF]

, 2023
Direct detection of DNA in complex biological samples relates to several problems regarding the selectivity and sensitivity of analyses. Therefore, DNA pre-extraction from biofluids is an emerging tool in biologically related fields.
Marek, Minárik, František, Foret, Helena, Hrušková, Roman, Řemínek   +3 more
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Liquid biopsy: a right tool in a right context? [PDF]

, 2022
Liquid biopsy is a minimally or noninvasive technique for finding that circulates tumor components in biofluids. Generally, blood is used but any biological fluid can be used such as urine, pleural effusion, and saliva.
Incorvaia L., Bazan V., Malapelle U., La Mantia M., Badalamenti G., Cutaia S., Capoluongo E., Rolfo C., Gristina V., Galvano A., Russo A.   +10 more
core   +1 more source

Liquid biopsy from research to clinical practice : focus on non-small cell lung cancer [PDF]

, 2021
: Introduction In the current era of personalized medicine, liquid biopsy has acquired a relevant importance in patient management of advanced stage non-small cell lung cancer (NSCLC).
Pisapia, Pasquale, De Miguel-Perez, Diego, Nuzzo, Pier Vitale, Addeo, Alfredo, Jantus-Lewintre, Eloisa, Rolfo, Christian, Bellosillo, Beatriz, Serrano, Maria Jose, Malapelle, Umberto, Arrieta, Oscar, Cardona, Andres F., Denninghoff, Valeria, Pauwels, Patrick, Troncone, Giancarlo, Raez, Luis E., Gandara, David R., Duran, Ignacio, Pickering, Edward M., Russo, Alessandro, Cristofanilli, Massimo, O'Byrne, Ken   +20 more
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Liquid biopsy.

Journal of biological regulators and homeostatic agents, 2019
During the early formation and growth of primary tumor (e.g., breast, colon, or prostate cancer), cells are shed from the primary tumor and then circulate through the bloodstream. Many of the major recent advances in targeted therapies have relied on the acquisition of tumor tissue via biopsy before initiation of therapy or after the onset of ...
Candotto, V, Pezzetti, F, Scarano, A, Agazzi, A, Spadari, F, Palmieri, A   +5 more
  +9 more sources