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Role of circulating tumor DNA and circulating tumor cells in breast cancer: History and updates [PDF]
SAGE Open Medicine, 2022 Circulating tumor DNA, cell-free DNA, and circulating tumor cells have been at the epitome of recent research in breast cancer. These forms of liquid biopsies have been used in monitoring disease progression, estimating the risk of relapse, and response ...
Julien Chedid +5 more
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Early detection of recurrent HPV+ hypopharyngeal squamous cell carcinoma by circulating tumor DNA
Otolaryngology Case Reports, 2023 Circulating tumor DNA is a liquid biomarker that offers a highly specific method to assess HPV-associated tumor burden via a blood draw. It has the potential for many clinical applications in cancer care, including prognostication, monitoring treatment ...
Derek D. Kao +2 more
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Circulating Tumor DNA in Pediatric Cancer
Frontiers in Molecular Biosciences, 2022 The measurement of circulating tumor DNA (ctDNA) has gained increasing prominence as a minimally invasive tool for the detection of cancer-specific markers in plasma.
Louise Doculara +11 more
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Circulating tumor DNA as prognostic markers for late stage NSCLC with bone metastasis
The International Journal of Biological Markers, 2018 Purpose: Bone metastases from non-small cell lung cancer (NSCLC) are common, and current prognostic stratification methods are challenging to predict outcomes.
Jiguang Jia +3 more
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Circulating Tumor DNA in Oncology [PDF]
Processes, 2021 When somatic cells in the human body undergo apoptosis or necrosis, the released DNA enters the bloodstream. This type of DNA is called cell-free DNA (cfDNA). In patients with cancer, DNA released from tumor cells is called circulating tumor DNA (ctDNA), which carries genetic alterations specific to tumor cells.
Saeko Sakaeda, Yoichi Naito
openaire +2 more sources
Analytical evaluation of circulating tumor DNA sequencing assays
Scientific ReportsIn China, circulating tumor DNA analysis is widely used and numerous assays are available. Systematic evaluation to help users make informed selections is needed.
Wenjin Li +6 more
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Clinical correlates of circulating cell-free DNA tumor fraction.
PLoS ONE, 2021 BackgroundOncology applications of cell-free DNA analysis are often limited by the amount of circulating tumor DNA and the fraction of cell-free DNA derived from tumor cells in a blood sample.
Joerg Bredno +4 more
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Fragment Length of Circulating Tumor DNA.
PLoS Genetics, 2016 Malignant tumors shed DNA into the circulation. The transient half-life of circulating tumor DNA (ctDNA) may afford the opportunity to diagnose, monitor recurrence, and evaluate response to therapy solely through a non-invasive blood draw.
Hunter R Underhill +9 more
doaj +3 more sources
Cell-free circulating tumor DNA in cancer [PDF]
Chinese Journal of Cancer, 2016 Cancer is a common cause of death worldwide. Despite significant advances in cancer treatments, the morbidity and mortality are still enormous. Tumor heterogeneity, especially intratumoral heterogeneity, is a significant reason underlying difficulties in
Zhen Qin +4 more
doaj +5 more sources
Molecular Oncology, 2019 Reliable biomarkers are required to evaluate and manage pancreatic ductal adenocarcinoma. Circulating tumor cells and circulating tumor DNA are shed into blood and can be relatively easily obtained from minimally invasive liquid biopsies for serial ...
Jee‐Soo Lee +4 more
doaj +2 more sources