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Clinical Application of Circulating Tumor DNA Analysis [PDF]
, 2022 Liquid biopsy using circulating tumor DNA helps overcome the limitations of conventional tissue testing. Non-invasive molecular profiling using circulating tumor DNA is increasingly being used to diagnose cancer, stratify risk, and select targeted ...
이승태, 원동주, 신새암
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Circulating DNA and Survival in Solid Tumors [PDF]
Cancer Epidemiology, Biomarkers & Prevention, 2016 Abstract Background: The ability to undertake molecular analysis to inform on prognosis and predictors of response to therapy is limited by accessibility of tissue. Measurement of total circulating free DNA (cfDNA) or circulating tumor DNA (ctDNA) in peripheral blood may allow easier access to tumor material and help to predict ...
Ocaña A +11 more
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The Role of Liquid Biopsy Analytes in Diagnosis, Treatment and Prognosis of Colorectal Cancer
Frontiers in Endocrinology, 2022 Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive tract worldwide and is a serious threat to human life and health. CRC occurs and develops in a multi-step, multi-stage, and multi-gene process, in which abnormal gene ...
JinHua He +8 more
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Applications of Circulating Tumor Cells and Circulating Tumor DNA in Precision Oncology for Breast Cancers [PDF]
, 2022 Liquid biopsies allow for the detection of cancer biomarkers such as circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA). Elevated levels of these biomarkers during cancer treatment could potentially serve as indicators of cancer progression
Singh, Balraj +9 more
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Translational Oncology, 2023 Background: Detection of circulating tumor-derived material (cTM) in the peripheral blood (PB) of cancer patients has been shown to be useful in early diagnosis, prediction of prognosis, and disease monitoring.
Eva Kristine Ruud Kjær +4 more
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Tumor Biology, 2020 Detection of circulating tumor DNA is a new noninvasive technique with potential roles in diagnostic, follow-up, and prognostic evaluation of patients with many types of solid tumors.
Mariana Cartaxo Alves +8 more
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Monitor tumor burden with circulating tumor DNA [PDF]
Cancer Biology & Therapy, 2013 There is a need to identify better biomarkers to monitor diseases and/or assess therapeutic responses. For those with cancer, one can identify DNA fragments that contain somatic mutations originating in the tumor DNA in plasma or serum. There have been several early studies suggesting that advances in sequencing technologies will allow identification ...
William D, Figg, Jim, Reid
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Circulating tumor DNA in Hodgkin lymphoma
Annals of Hematology, 2022 Abstract Somatic mutations of genes involved in NF-κB, PI3K/AKT, NOTCH, and JAK/STAT signaling pathways play an important role in the pathogenesis of Hodgkin lymphoma (HL). HL tumor cells form only about 5% of the tumor mass; however, it was shown that HL tumor-derived DNA could be detected in the bloodstream.
Maria Maco +6 more
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Technical Aspects for the Evaluation of Circulating Nucleic Acids (CNAs): Circulating Tumor DNA (ctDNA) and Circulating MicroRNAs [PDF]
, 2017 Circulating nucleic acids (CNAs), for example, circulating tumor DNA (ctDNA) and circulating microRNA (miRNA), represent promising biomarkers in several diseases including cancer.
CIACCIO, Marcello +11 more
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Plasma DNA concentration as a predictor of mortality and sepsis in critically ill patients [PDF]
, 2006 Introduction: Risk stratification of severely ill patients remains problematic, resulting in increased interest in potential circulating markers, such as cytokines, procalcitonin and brain natriuretic peptide. Recent reports have indicated the usefulness
Bennett, ED +4 more
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