Results 21 to 30 of about 2,960,910 (293)
Molecular Oncology, 2019 Reliable biomarkers are required to evaluate and manage pancreatic ductal adenocarcinoma. Circulating tumor cells and circulating tumor DNA are shed into blood and can be relatively easily obtained from minimally invasive liquid biopsies for serial ...
Jee‐Soo Lee +4 more
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Circulating Tumor DNA in Oncology [PDF]
Processes, 2021 When somatic cells in the human body undergo apoptosis or necrosis, the released DNA enters the bloodstream. This type of DNA is called cell-free DNA (cfDNA). In patients with cancer, DNA released from tumor cells is called circulating tumor DNA (ctDNA), which carries genetic alterations specific to tumor cells.
Saeko Sakaeda, Yoichi Naito
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Cell-free circulating tumor DNA in cancer [PDF]
Chinese Journal of Cancer, 2016 Cancer is a common cause of death worldwide. Despite significant advances in cancer treatments, the morbidity and mortality are still enormous. Tumor heterogeneity, especially intratumoral heterogeneity, is a significant reason underlying difficulties in
Zhen Qin +4 more
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Liquid biopsy in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA [PDF]
Molecular Cancer, 2019 Hepatocellular carcinoma (HCC) is one of the most common cancers and a leading cause of death worldwide. Due to latent liver disease, late diagnosis, and nonresponse to systemic treatments, surgical resection and/or biopsy specimens are still generally ...
Qianwei Ye +3 more
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Molecular features unique to circulating tumor DNA enable the tumor-naïve liquid biopsy of glioblastoma [PDF]
npj Precision OncologyGlioblastoma is the most common and deadly brain cancer in adults. Although the disease disrupts the blood-brain barrier and exposes the tumor to the systemic circulation, using circulating cell-free DNA as a non-invasive biomarker for diagnosing ...
Hunter R. Underhill +23 more
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Circulating cell-free DNA and circulating tumor cells, the “liquid biopsies” in ovarian cancer
Journal of Ovarian Research, 2017 Limited understanding of ovarian cancer (OC) genome portrait has hindered the therapeutic advances. The serial monitoring of tumor genotypes is becoming increasingly attainable with circulating cell-free DNA (cf-DNA) and circulating tumor cells (CTCs ...
Xianliang Cheng +3 more
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Circulating Tumor Cells and Circulating Tumor DNA: Challenges and Opportunities on the Path to Clinical Utility [PDF]
Clinical Cancer Research, 2015 Abstract Recent technological advances have enabled the detection and detailed characterization of circulating tumor cells (CTC) and circulating tumor DNA (ctDNA) in blood samples from patients with cancer. Often referred to as a “liquid biopsy,” CTCs and ctDNA are expected to provide real-time monitoring of tumor evolution and ...
Ignatiadis, Michail +2 more
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Liquid Biopsy as a Method for Minimally Invasive Diagnosis of Thyroid Cancer [PDF]
Клиническая практика, 2023 Thyroid cancer is the 9th most common cancer in the world. The five-year survival rate for this disease is over 98%. However, in some patients there are cases of rapidly progressive treatment-resistant cancer that cannot be differed from poor-invasive ...
Tagir I. Rakhmatullin +3 more
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Biosensors, 2022 While patients with resectable pancreatic ductal adenocarcinoma (PDAC) show improved survival compared to their non-resectable counterparts, survival remains low owing to occult metastatic disease and treatment resistance.
Pablo J. Dopico +7 more
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Clinical Application of Circulating Tumor DNA Analysis [PDF]
, 2022 Liquid biopsy using circulating tumor DNA helps overcome the limitations of conventional tissue testing. Non-invasive molecular profiling using circulating tumor DNA is increasingly being used to diagnose cancer, stratify risk, and select targeted ...
이승태, 원동주, 신새암
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