Results 41 to 50 of about 2,960,910 (293)
ctDNA and CTCs in Liquid Biopsy – Current Status and Where We Need to Progress
Computational and Structural Biotechnology Journal, 2018 We discuss the current status of liquid biopsy and its advantages and challenges with a focus on pre-analytical sample handling, technologies and workflows. The potential of circulating tumor cells and circulating tumor DNA is pointed out and an overview
Martin H.D. Neumann +3 more
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Blood-Based Analyses of Cancer: Circulating Tumor Cells and Circulating Tumor DNA [PDF]
Cancer Discovery, 2014 Abstract The ability to study nonhematologic cancers through noninvasive sampling of blood is one of the most exciting and rapidly advancing fields in cancer diagnostics. This has been driven both by major technologic advances, including the isolation of intact cancer cells and the analysis of cancer cell–derived DNA from blood samples ...
Daniel A, Haber, Victor E, Velculescu
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The importance of circulating tumor products as „liquid biopsies” in colorectal cancer
Journal of Mind and Medical Sciences, 2018 Liquid biopsies represent an array of plasma analysis tests that are studied to evaluate and identify circulating tumor products, especially circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA).
Alina Miscoci +6 more
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Base composition of DNA in adenovirus-12-induced tumor [PDF]
, 1969 A series of experiments was conducted to study the base composition of DNA in AVl2-induced tumor and host cells by paper chromatography, and it was found that DNA per cent. guanine-cystosine contents were around 42 % in both of them. The base composition
Ohmori, Masaki
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The Role of Circulating Tumor DNA Analyses
, 2022 All cells shed DNA into circulation (cell-free DNA; cfDNA) based on various processes like apoptosis, necrosis, or active release (Stroun et al., Clin Chim Acta 313(1–2):139–142, 2001; Schwarzenbach et al., Nat Rev Cancer 11(6):426–437, 2011). A fraction of the cfDNA may be circulating tumor DNA (ctDNA) that represents the DNA released from cancer ...
Christensen, Emil +2 more
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Clinical and Experimental Obstetrics & Gynecology, 2023 This paper encourages understanding a non-invasive technology—the “Liquid biopsy”, including circulating tumor cells (CTCs) and circulating tumor DNA (ct DNA) technology, that can help diagnose early cancers, cancer relapse, and resistance to ...
Felix Wong +2 more
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Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden
Nature Communications, 2021 Circulating tumour DNA (ctDNA) represents a non-invasive option to monitor cancer progression. Here, the authors perform deep sequencing of plasma cell-free DNA, and find that nucleosome-dependent cfDNA degradation at 6 specific regulatory regions is ...
Guanhua Zhu +19 more
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The Prognostic Significance of Circulating Tumor Cells in Patients with Pancreatobiliary Cancer
, 2023 Background: Circulating tumor cells are cancer cells which separate from the primary tumor and enter systemic circulation. In this study, it was aimed to examine the relationship between circulating tumor cells isolated and identified from the peripheral
Başbınar, Yasemin +28 more
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, 2012 Testing for mutations in the KRAS oncogene for patients with metastatic colorectal cancer (mCRC) is generally performed using DNA from formalin-fixed paraffin-embedded tumor tissue; however, access to specimens can be limited and analysis challenging ...
John Smith +6 more
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Detection of Tumor Cell-Specific mRNA in the Peripheral Blood of Patients with Breast Cancer-Evaluation of Several Markers with Real-Time Reverse Transcription-PCR [PDF]
, 2013 It is widely known that cells from epithelial tumors, e. g., breast cancer, detach from their primary tissue and enter blood circulation. We show that the presence of circulating tumor cells (CTCs) in samples of patients with primary and metastatic ...
Simone Hofmann +20 more
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