Results 31 to 40 of about 3,179,450 (287)
The importance of circulating tumor products as „liquid biopsies” in colorectal cancer
Liquid biopsies represent an array of plasma analysis tests that are studied to evaluate and identify circulating tumor products, especially circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA).
Alina Miscoci +6 more
doaj +1 more source
Blood-Based Analyses of Cancer: Circulating Tumor Cells and Circulating Tumor DNA [PDF]
Abstract The ability to study nonhematologic cancers through noninvasive sampling of blood is one of the most exciting and rapidly advancing fields in cancer diagnostics. This has been driven both by major technologic advances, including the isolation of intact cancer cells and the analysis of cancer cell–derived DNA from blood samples ...
Daniel A, Haber, Victor E, Velculescu
openaire +2 more sources
The Role of Circulating Tumor DNA Analyses
All cells shed DNA into circulation (cell-free DNA; cfDNA) based on various processes like apoptosis, necrosis, or active release (Stroun et al., Clin Chim Acta 313(1–2):139–142, 2001; Schwarzenbach et al., Nat Rev Cancer 11(6):426–437, 2011). A fraction of the cfDNA may be circulating tumor DNA (ctDNA) that represents the DNA released from cancer ...
Christensen, Emil +2 more
openaire +1 more source
Supplementary Table from Circulating Tumor DNA Is Associated with Response and Survival in Patients with Advanced ...
Aaron R. Thorner (15035421) +11 more
core +5 more sources
Supplementary Data from Tumor-Naïve Multimodal Profiling of Circulating Tumor DNA in Head and Neck Squamous Cell ...
John N. Waldron (15032258) +18 more
core +1 more source
Plasma DNA concentration as a predictor of mortality and sepsis in critically ill patients [PDF]
Introduction: Risk stratification of severely ill patients remains problematic, resulting in increased interest in potential circulating markers, such as cytokines, procalcitonin and brain natriuretic peptide. Recent reports have indicated the usefulness
Bennett, ED +4 more
core +1 more source
This paper encourages understanding a non-invasive technology—the “Liquid biopsy”, including circulating tumor cells (CTCs) and circulating tumor DNA (ct DNA) technology, that can help diagnose early cancers, cancer relapse, and resistance to ...
Felix Wong +2 more
doaj +1 more source
Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden
Circulating tumour DNA (ctDNA) represents a non-invasive option to monitor cancer progression. Here, the authors perform deep sequencing of plasma cell-free DNA, and find that nucleosome-dependent cfDNA degradation at 6 specific regulatory regions is ...
Guanhua Zhu +19 more
doaj +1 more source
Testing for mutations in the KRAS oncogene for patients with metastatic colorectal cancer (mCRC) is generally performed using DNA from formalin-fixed paraffin-embedded tumor tissue; however, access to specimens can be limited and analysis challenging ...
John Smith +6 more
core +1 more source

