Results 11 to 20 of about 305,738 (309)

Detection of circulating tumor-derived material in peripheral blood of pediatric sarcoma patients: A systematic review

Translational Oncology, 2023
Background: Detection of circulating tumor-derived material (cTM) in the peripheral blood (PB) of cancer patients has been shown to be useful in early diagnosis, prediction of prognosis, and disease monitoring.
Eva Kristine Ruud Kjær, Christian Bach Vase, Maria Rossing, Lise Barlebo Ahlborn, Lisa Lyngsie Hjalgrim   +4 more
doaj   +1 more source

The Role of Liquid Biopsy Analytes in Diagnosis, Treatment and Prognosis of Colorectal Cancer

Frontiers in Endocrinology, 2022
Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive tract worldwide and is a serious threat to human life and health. CRC occurs and develops in a multi-step, multi-stage, and multi-gene process, in which abnormal gene ...
JinHua He, NaiTe Xi, ZePing Han, WenFeng Luo, Jian Shen, ShengBo Wang, JianHao Li, ZhongHui Guo, HanWei Cheng   +8 more
doaj   +1 more source

Monitor tumor burden with circulating tumor DNA [PDF]

Cancer Biology & Therapy, 2013
There is a need to identify better biomarkers to monitor diseases and/or assess therapeutic responses. For those with cancer, one can identify DNA fragments that contain somatic mutations originating in the tumor DNA in plasma or serum. There have been several early studies suggesting that advances in sequencing technologies will allow identification ...
William D, Figg, Jim, Reid
openaire   +2 more sources

Increased circulating tumor DNA as a noninvasive biomarker of early treatment response in patients with metastatic ovarian carcinoma: A pilot study

Tumor Biology, 2020
Detection of circulating tumor DNA is a new noninvasive technique with potential roles in diagnostic, follow-up, and prognostic evaluation of patients with many types of solid tumors.
Mariana Cartaxo Alves, Fernando Luiz Affonso Fonseca, Alayne Magalhães Trindade Domingues Yamada, Lílian Arruda do Rego Barros, André Lopes, Luana Carolina Ferreira Fiuza Silva, Ariana Sales Luz, Felipe José Silva Melo Cruz, Auro Del Giglio   +8 more
doaj   +1 more source

Circulating Tumor DNA in Oncology [PDF]

Processes, 2021
When somatic cells in the human body undergo apoptosis or necrosis, the released DNA enters the bloodstream. This type of DNA is called cell-free DNA (cfDNA). In patients with cancer, DNA released from tumor cells is called circulating tumor DNA (ctDNA), which carries genetic alterations specific to tumor cells.
Saeko Sakaeda, Yoichi Naito
openaire   +1 more source

Circulating tumor DNA in Hodgkin lymphoma

Annals of Hematology, 2022
Abstract Somatic mutations of genes involved in NF-κB, PI3K/AKT, NOTCH, and JAK/STAT signaling pathways play an important role in the pathogenesis of Hodgkin lymphoma (HL). HL tumor cells form only about 5% of the tumor mass; however, it was shown that HL tumor-derived DNA could be detected in the bloodstream.
Maria Maco, Kristyna Kupcova, Vaclav Herman, Iva Ondeckova, Tomas Kozak, Heidi Mocikova, Ondrej Havranek   +6 more
openaire   +2 more sources

The rationale for liquid biopsy in colorectal cancer: focus on circulating tumor cells [PDF]

, 2015
Capturing circulating tumor cells (CTCs) and/or circulating tumor DNA from blood, which represents a precious source of biological material derived from both primary and metastatic tumors, has been named a 'liquid biopsy'. While the circulating tumor DNA
Carletti, Raffaella, Cortesi, Enrico, DI GIOIA, Cira Rosaria Tiziana, Gazzaniga, Paola, Gradilone, Angela, Nicolazzo, Chiara, Raimondi, Cristina   +6 more
core   +1 more source

Next Generation Sequencing Assay for Detection of Circulating HPV DNA (cHPV-DNA) in Patients Undergoing Radical (Chemo)Radiotherapy in Anal Squamous Cell Carcinoma (ASCC). [PDF]

, 2020
Background: Following chemo-radiotherapy (CRT) for human papilloma virus positive (HPV+) anal squamous cell carcinoma (ASCC), detection of residual/recurrent disease is challenging.
Augustin, Y, Bhide, S, Cutts, RJ, Fenwick, K, Garcia-Murillas, I, Gilbert, DC, Harrington, K, Lee, JY, Matthews, N, Turner, NC, White, I   +10 more
core   +3 more sources

Specific antigen of tumor cell transformed by DNA extracted from SV-40 virus [PDF]

, 1967
In the immunofluorescent study it has been revealed that rabbit sera immunized with transformed cells induced by SV-40 DNA, produce circulating antibody capable of re:lcting with intranuclear antigens synthesized by SV-40 complyte virus transforming ...
Grace, James T., Hayashi, Kenj, Kimoto, Tetsuo, Okada, Shigeru, Shigehisa, Morio, Sogabe, Koichi   +5 more
core   +1 more source

Circulating Cell-Free DNA in Dogs with Mammary Tumors: Short and Long Fragments and Integrity Index [PDF]

, 2017
Circulating cell-free DNA (cfDNA) has been considered an interesting diagnostic/prognostic plasma biomarker in tumor-bearing subjects. In cancer patients, cfDNA can hypothetically derive from tumor necrosis/apoptosis, lysed circulating cells, and some ...
A Asmarinah, A Fawzy, A Jemal, A Matos, Alessandro Sammarco, Andrea Saccani, Antonio Mollo, BG Wang, BT Kurien, C Alix-Panabières, C Qian, CH Lee, Chiara Bedin, Chiara Romualdi, D Bostock, D El-Gayar, D Madhavan, D Merlo, Davide Trez, DMW Schaefer, Donato Nitti, E Coustan-Smith, E Gormally, EM Tan, F Salvianti, FH Igney, GB Gelaleti, Giorgia Beffagna, H Schwarzenbach, H Schwarzenbach, J Beck, J Ferlay, JC Thompson, K Jung, K Pilichou, K Sorenmo, K Sorenmo, Kristy L. Richards, KS Borge, L Ouyang, L Pena, L Pena, Laura Cavicchioli, LE Lowes, M Agostini, M Geng, M Goldschmidt, M Shackleton, M Stroun, M Stroun, Marco Agostini, Marta Mainenti, MB Giacona, Michelangelo Campanella, MV Jain, N Sleeckx, N Umetani, N Umetani, P Anker, P Hofman, P Rivera, R Agassi, R Brodey, R Kumaraguruparan, R Kumaraguruparan, Raffaella De Maria, Re Ellsworth, S Baspinar, S Cargnin, S Iqbal, S Jahr, S Volik, SA Leon, Silvia Ferro, T Hao, T Imamura, T Skvortsova, Valentina Zappulli, W Ayala, W Wang   +79 more
core   +6 more sources