Early detection of recurrent HPV+ hypopharyngeal squamous cell carcinoma by circulating tumor DNA [PDF]
Circulating tumor DNA is a liquid biomarker that offers a highly specific method to assess HPV-associated tumor burden via a blood draw. It has the potential for many clinical applications in cancer care, including prognostication, monitoring treatment ...
Derek D. Kao +2 more
doaj +2 more sources
Circulating tumor DNA as prognostic markers for late stage NSCLC with bone metastasis [PDF]
Purpose: Bone metastases from non-small cell lung cancer (NSCLC) are common, and current prognostic stratification methods are challenging to predict outcomes.
Jiguang Jia +3 more
doaj +2 more sources
Circulating Tumor DNA in Oncology [PDF]
When somatic cells in the human body undergo apoptosis or necrosis, the released DNA enters the bloodstream. This type of DNA is called cell-free DNA (cfDNA). In patients with cancer, DNA released from tumor cells is called circulating tumor DNA (ctDNA), which carries genetic alterations specific to tumor cells.
Saeko Sakaeda, Yoichi Naito
openaire +3 more sources
Analytical evaluation of circulating tumor DNA sequencing assays [PDF]
In China, circulating tumor DNA analysis is widely used and numerous assays are available. Systematic evaluation to help users make informed selections is needed.
Wenjin Li +6 more
doaj +2 more sources
Analysis of tutor circulating DNA using Next Generation ...
Alexandru Salceanu (9303227)
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Circulating cell-free DNA and circulating tumor cells, the “liquid biopsies” in ovarian cancer [PDF]
Limited understanding of ovarian cancer (OC) genome portrait has hindered the therapeutic advances. The serial monitoring of tumor genotypes is becoming increasingly attainable with circulating cell-free DNA (cf-DNA) and circulating tumor cells (CTCs ...
Xianliang Cheng +3 more
doaj +2 more sources
Circulating Tumor Cells and Circulating Tumor DNA: Challenges and Opportunities on the Path to Clinical Utility [PDF]
Abstract Recent technological advances have enabled the detection and detailed characterization of circulating tumor cells (CTC) and circulating tumor DNA (ctDNA) in blood samples from patients with cancer. Often referred to as a “liquid biopsy,” CTCs and ctDNA are expected to provide real-time monitoring of tumor evolution and ...
Ignatiadis, Michail +2 more
openaire +5 more sources
For patients with BRAF wild-type stage III and IV melanoma, there is an urgent clinical need to identify prognostic biomarkers and biomarkers predictive of treatment response.
Lauren G. Aoude +13 more
openaire +2 more sources
Blood-based biomarkers in breast cancer: From proteins to circulating tumor cells to circulating tumor DNA [PDF]
Biomarkers are the key to personalized treatment in patients with breast cancer. While tissue biomarkers are most useful in determining prognosis and upfront predicting response to therapy, circulating protein biomarkers such as CA 15-3 and ...
Michael J Duffy +2 more
doaj +2 more sources
Supplementary Figure from Tumor-Naïve Multimodal Profiling of Circulating Tumor DNA in Head and Neck Squamous Cell Carcinoma [PDF]
Supplementary Figure from Tumor-Naïve Multimodal Profiling of Circulating Tumor DNA in Head and Neck Squamous Cell ...
John N. Waldron (15032258) +18 more
core +13 more sources

