The Mechanical Fingerprint of Circulating Tumor Cells (CTCs) in Breast Cancer Patients [PDF]
Cancers, 2021 Circulating tumor cells (CTCs) are a potential predictive surrogate marker for disease monitoring. Due to the sparse knowledge about their phenotype and its changes during cancer progression and treatment response, CTC isolation remains challenging. Here
Erik Morawetz +2 more
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Dangerous Liaisons: Circulating Tumor Cells (CTCs) and Cancer-Associated Fibroblasts (CAFs) [PDF]
Cancers, 2020 The crosstalk between cancer cells and the tumor microenvironment (TME) is a key determinant of cancer metastasis. Cancer-associated fibroblasts (CAFs), one of the main cellular components of TME, promote cancer cell invasion and dissemination through ...
Inés Martinez Pena, Roberto Pineiro
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CTC-Derived Models: A Window into the Seeding Capacity of Circulating Tumor Cells (CTCs) [PDF]
Cells, 2019 Metastasis is the main cause of cancer-related death owing to the blood-borne dissemination of circulating tumor cells (CTCs) early in the process. A rare fraction of CTCs harboring a stem cell profile and tumor initiation capacities is thought to possess the clonogenic potential to seed new lesions. The highest plasticity has been generally attributed
Patrycja Pawlikowska +2 more
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Gauging the Impact of Cancer Treatment Modalities on Circulating Tumor Cells (CTCs) [PDF]
Cancers, 2020 The metastatic cascade consists of multiple complex steps, but the belief that it is a linear process is diminishing. In order to metastasize, cells must enter the blood vessels or body cavities (depending on the cancer type) via active or passive mechanisms. Once in the bloodstream and/or lymphatics, these cancer cells are now termed circulating tumor
Katarina Chang +2 more
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Recent Progress in Enhanced Cancer Diagnosis, Prognosis, and Monitoring Using a Combined Analysis of the Number of Circulating Tumor Cells (CTCs) and Other Clinical Parameters [PDF]
Cancers, 2023 Ping-Hei Chen
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Cancer Stem Cells (CSCs), Circulating Tumor Cells (CTCs) and Their Interplay with Cancer Associated Fibroblasts (CAFs): A New World of Targets and Treatments [PDF]
Cancers, 2022 Franco Stella +2 more
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Circulating Tumor Cells (CTCs): A Unique Model of Cancer Metastases and Non-invasive Biomarkers of Therapeutic Response [PDF]
Frontiers in Genetics, 2021 Yang Xu, Changzheng Du, Hailiang Hu
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iScience, 2022 Summary: Matching the treatment to an individual patient’s tumor state can increase therapeutic efficacy and reduce tumor recurrence. Circulating tumor cells (CTCs) derived from solid tumors are promising subjects for theragnostic analysis.
Jia-Yang Chen +17 more
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Circulating Tumor Cells and Extracellular Nucleic Acids in Breast Cancer [PDF]
Kosin Medical Journal, 2012 Circulating tumor cells (CTCs) are defined as tumor cells circulating in the peripheral blood of patients, shed from either the primary tumor or from its metastases. The detection of circulating tumor cells (CTCs) in the peripheral blood of breast cancer
Dong Won Ryu, Chung Han Lee
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Clinical Applications of Cancer-Associated Cells Present in the Blood of Cancer Patients
Biomedicines, 2022 The ability to obtain tumor material from cells in the blood of cancer patients provides a significant benefit over the use of tumor tissue as a diagnostic to make treatment decisions.
Cha-Mei Tang, Daniel L. Adams
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