3D printed microfluidic devices for circulating tumor cells (CTCs) isolation. [PDF]
Biosens Bioelectron, 2020 Isolation of circulating tumor cells (CTCs) from blood samples has important prognostic and therapeutic implications for cancer treatments, but the process is very challenging due to the low concentration of CTCs.
Chen J +6 more
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Dangerous Liaisons: Circulating Tumor Cells (CTCs) and Cancer-Associated Fibroblasts (CAFs). [PDF]
Cancers (Basel), 2020 The crosstalk between cancer cells and the tumor microenvironment (TME) is a key determinant of cancer metastasis. Cancer-associated fibroblasts (CAFs), one of the main cellular components of TME, promote cancer cell invasion and dissemination through ...
Hurtado P, Martínez-Pena I, Piñeiro R.
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CTC-Derived Models: A Window into the Seeding Capacity of Circulating Tumor Cells (CTCs). [PDF]
Cells, 2019 Metastasis is the main cause of cancer-related death owing to the blood-borne dissemination of circulating tumor cells (CTCs) early in the process. A rare fraction of CTCs harboring a stem cell profile and tumor initiation capacities is thought to possess the clonogenic potential to seed new lesions. The highest plasticity has been generally attributed
Tayoun T +5 more
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Gauging the Impact of Cancer Treatment Modalities on Circulating Tumor Cells (CTCs). [PDF]
Cancers (Basel), 2020 The metastatic cascade consists of multiple complex steps, but the belief that it is a linear process is diminishing. In order to metastasize, cells must enter the blood vessels or body cavities (depending on the cancer type) via active or passive mechanisms. Once in the bloodstream and/or lymphatics, these cancer cells are now termed circulating tumor
Mathias TJ +3 more
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Recent Progress in Enhanced Cancer Diagnosis, Prognosis, and Monitoring Using a Combined Analysis of the Number of Circulating Tumor Cells (CTCs) and Other Clinical Parameters. [PDF]
Cancers (Basel), 2023 Nguyen TNA +4 more
europepmc +2 more sources
iScience, 2022 Summary: Matching the treatment to an individual patient’s tumor state can increase therapeutic efficacy and reduce tumor recurrence. Circulating tumor cells (CTCs) derived from solid tumors are promising subjects for theragnostic analysis.
Jia-Yang Chen +17 more
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Circulating Tumor Cells and Extracellular Nucleic Acids in Breast Cancer [PDF]
Kosin Medical Journal, 2012 Circulating tumor cells (CTCs) are defined as tumor cells circulating in the peripheral blood of patients, shed from either the primary tumor or from its metastases. The detection of circulating tumor cells (CTCs) in the peripheral blood of breast cancer
Dong Won Ryu, Chung Han Lee
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Clinical Applications of Cancer-Associated Cells Present in the Blood of Cancer Patients
Biomedicines, 2022 The ability to obtain tumor material from cells in the blood of cancer patients provides a significant benefit over the use of tumor tissue as a diagnostic to make treatment decisions.
Cha-Mei Tang, Daniel L. Adams
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Frontiers in Pharmacology, 2022 The practice of medicine has steadily employed less invasive methods to obtain information derived from the tumor to guide clinical management of patients. Liquid biopsy—the sampling of blood—is a non-invasive method for generating information previously
Eric P. Kaldjian +6 more
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Stem cell-like circulating tumor cells indicate poor prognosis in gastric cancer
Archives of Medical Science, 2020 Introduction Circulating tumor cells (CTCs) have the characteristics of cancer stem cells and play an important role in the recurrence and metastasis of tumors.
Wang Yi-Wen +4 more
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