Results 41 to 50 of about 5,745,790 (267)

Identification and gene expression analysis of circulating tumor cells with high expression of KRAS in pancreatic cancer

open access: yesAIP Advances, 2023
This study aims to establish a highly sensitive and specific method for single cell screening and identification of KRAS+/epithelial cell adhesion molecules (EpCAMs)/vimentin+/pancreatic cancer circulating tumor cells (CTCs) and to explore the clinical ...
Zhiqiang Zheng   +3 more
doaj   +1 more source

Circulating tumor cells (CTCs) during TISOC1 treatment.

open access: yes, 2015
Circulating tumor cells (CTCs) during TISOC1 treatment.
Andreas Dietz (771782)   +12 more
core   +1 more source

Hydro-Seq enables contamination-free high-throughput single-cell RNA-sequencing for circulating tumor cells

open access: yesNature Communications, 2019
Transcriptome analysis of circulating tumor cells (CTCs) provides insights into monitoring target therapeutics and underlying tumor metastasis. Here the authors present Hydro-Seq, a contamination-free high-throughput hydrodynamic scRNA-seq barcoding ...
Yu-Heng Cheng   +14 more
doaj   +1 more source

Size-Based and Non-Affinity Based Microfluidic Devices for Circulating Tumor Cell Enrichment and Characterization

open access: yes, 2016
Circulating Tumor Cells (CTCs) are tumor cells found in cancer patients’ peripheral blood. Enumeration of CTCs can provide prognosis information for cancer management (Cristofanilli et al., N Engl J Med 351(8):781–791, 2004; Cohen et al., J Clin Oncol 26(
Richard J. Cote   +7 more
core   +1 more source

Perspectives on the Functional Characterization and In Vitro Maintenance of Circulating Tumor Cells

open access: yes, 2016
Circulating tumor cells (CTCs) that detach and migrate from primary tumors are implicated in the metastatic spread of cancer. The identification of CTCs in peripheral blood samples has been associated with poor survival outcomes in various cancer types ...
Ramdane Harouaka   +15 more
core   +1 more source

Current detection technologies for circulating tumor cells

open access: yes, 2017
Circulating tumor cells (CTCs) are cancer cells that circulate in the blood stream after being naturally shed from original or metastatic tumors, and can lead to a new fatal metastasis.
Zheyu Shen   +5 more
core   +1 more source

Three-Dimensional Telomeric Analysis of Isolated Circulating Tumor Cells (CTCs) Defines CTC Subpopulations

open access: yesTranslational Oncology, 2013
Circulating tumor cells (CTCs) have been identified with the potential to serve as suitable biomarkers for tumor stage and progression, but the availability of effective isolation technique(s) coupled with detailed molecular characterization have been the challenges encountered in making CTCs clinically relevant.
Adebayo Awe, Julius   +7 more
openaire   +3 more sources

Association of a novel circulating tumor DNA next-generating sequencing platform with circulating tumor cells (CTCs) and CTC clusters in metastatic breast cancer [PDF]

open access: yesBreast Cancer Research, 2019
Abstract Purpose Liquid biopsies, including circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs), can be used to understand disease prognosis, tumor heterogeneity, and dynamic response to treatment in metastatic breast cancer (MBC).
Davis A. A.   +11 more
openaire   +3 more sources

Modeling of circulating tumor cell (CTC) and platelet interaction in capillaries

open access: yesBook of Proceedings, 2023
The main function of platelets is to bind to the sites of the damaged vessels to stop bleeding. However, in cancer patients, activated platelets adhere to circulating tumor cells and accelerate metastatic spreading. To examine the biophysical conditions needed for CTC arrest, we use a custom-built viscoelastic solid–fluid 2D computational model that ...
Aleksandar Nikolić   +3 more
openaire   +2 more sources

Insights on CTC Biology and Clinical Impact Emerging from Advances in Capture Technology

open access: yesCells, 2019
Circulating tumor cells (CTCs) and circulating tumor microemboli (CTM) have been shown to correlate negatively with patient survival. Actual CTC counts before and after treatment can be used to aid in the prognosis of patient outcomes.
Patrick C. Bailey, Stuart S. Martin
doaj   +1 more source

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