Detection Methods and Clinical Applications of Circulating Tumor Cells in Breast Cancer
Circulating Tumor Cells (CTCs) are cancer cells that split away from the primary tumor and appear in the circulatory system as singular units or clusters, which was first reported by Dr. Thomas Ashworth in 1869.
Hongyi Zhang +11 more
doaj +1 more source
Integration of biomimicry and nanotechnology for significantly improved detection of circulating tumor cells (CTCs) [PDF]
Seungpyo Hong, Az Wang, Ja Hye Myung
exaly +2 more sources
The importance of circulating tumor products as „liquid biopsies” in colorectal cancer
Liquid biopsies represent an array of plasma analysis tests that are studied to evaluate and identify circulating tumor products, especially circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA).
Alina Miscoci +6 more
doaj +1 more source
Background Circulating tumor cells (CTCs) have been a non-invasive technique which allows investigation of tumor characteristics. The purpose of this study was to investigate the relationship between circulating tumor cells and colorectal cancer. Methods
Yuhao He +3 more
doaj +1 more source
Detection of Tumor Cell-Specific mRNA in the Peripheral Blood of Patients with Breast Cancer-Evaluation of Several Markers with Real-Time Reverse Transcription-PCR [PDF]
It is widely known that cells from epithelial tumors, e. g., breast cancer, detach from their primary tissue and enter blood circulation. We show that the presence of circulating tumor cells (CTCs) in samples of patients with primary and metastatic ...
Simone Hofmann +20 more
core +1 more source
Background Liquid biopsy provides a non-invasive approach that enables detecting circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) using blood specimens and theoretically benefits early finding primary tumor or monitoring treatment ...
Jianzhu Xie +6 more
doaj +1 more source
Recent Update Roles of Magnetic Nanoparticles in Circulating Tumor Cell (CTC)/Non-CTC Separation
Metastasis of cancer is a major cause of death worldwide. Circulating tumor cells (CTCs) are important in the metastatic process of cancer. CTCs are able to circulate in the bloodstream. Therefore, they can be used as biomarkers of metastasis. However, CTCs are rare when compared to a large number of blood cells in the blood. Many CTC detection methods
Chawapon Pipatwatcharadate +2 more
openaire +3 more sources
Cultured circulating tumor cells and their derived xenografts for personalized oncology
Recent cancer research has demonstrated the existence of circulating tumor cells (CTCs) in cancer patient's blood. Once identified, CTC biomarkers will be invaluable tools for clinical diagnosis, prognosis and treatment.
Ruoxiang Wang +14 more
doaj +1 more source
The potential for liquid biopsies in the precision medical treatment of breast cancer
Currently the clinical management of breast cancer relies on relatively few prognostic/predictive clinical markers (estrogen receptor, progesterone receptor, HER2), based on primary tumor biology.
Victoria A. Forte +5 more
doaj +1 more source
How to Agree on a CTC: Evaluating the Consensus in Circulating Tumor Cell Scoring [PDF]
AbstractFor using counts of circulating tumor cells (CTCs) in the clinic to aid a physician's decision, its reported values will need to be accurate and comparable between institutions. Many technologies have become available to enumerate and characterize CTCs, thereby showing a large range of reported values.
Zeune +6 more
openaire +4 more sources

