Results 11 to 20 of about 5,745,790 (267)

The Mechanical Fingerprint of Circulating Tumor Cells (CTCs) in Breast Cancer Patients. [PDF]

Cancers (Basel), 2021
Circulating tumor cells (CTCs) are a potential predictive surrogate marker for disease monitoring. Due to the sparse knowledge about their phenotype and its changes during cancer progression and treatment response, CTC isolation remains challenging. Here
Nel I, Morawetz EW, Tschodu D, Käs JA, Aktas B.   +4 more
europepmc   +6 more sources

Technical Aspects for the Evaluation of Circulating Tumor Cells (CTCs)

, 2017
Liquid biopsy is considered a valid strategy to improve patients’ selection and treatment monitoring in clinical practice. Indeed Circulating Tumor Cells (CTCs) represent an important component of liquid biopsy and their clinical evaluation is becoming ...
Bazan, Viviana, Ciaccio, M., Viviana Bazan, Di Stefano, A. B., Castiglia, M., M. Castiglia, M. Ciaccio, A. B. Di Stefano   +7 more
core   +2 more sources

Research status of self-seeding by circulating tumor cells in tumor progression

Kouqiang hemian waike zazhi
Self-seeding, a distinct biological behavior of circulating tumor cells (CTCs), is prevalent in many malignant tumors and closely linked to tumor progression.
DAI Zhenlin, XU Qin
doaj   +2 more sources

Multigene profiling of single circulating tumor cells

Molecular & Cellular Oncology, 2017
Numerous techniques for isolating circulating tumor cells (CTCs) have been developed. Concurrently, single-cell techniques that can reveal molecular components of CTCs have become widely available.
Seung-min Park, Dawson J. Wong, Chin Chun Ooi, Jared C. Nesvet, Viswam S. Nair, Shan X. Wang, Sanjiv S. Gambhir   +6 more
doaj   +2 more sources

Natural killer cells: the immune frontline against circulating tumor cells

Journal of Experimental & Clinical Cancer Research
Natural killer (NK) play a key role in controlling tumor dissemination by mediating cytotoxicity towards cancer cells without the need of education. These cells are pivotal in eliminating circulating tumor cells (CTCs) from the bloodstream, thus limiting
Doryan Masmoudi, Martin Villalba, Catherine Alix-Panabières   +2 more
doaj   +2 more sources

Circulating tumor cells (CTCs) and hTERT gene expression in CTCs for radiotherapy effect with lung cancer. [PDF]

BMC Cancer, 2023
Abstract Background Circulating tumor cells (CTCs) are important biological indicators of the lung cancer prognosis, and CTC counting and typing may provide helpful biological information for the diagnosis and treatment of lung cancer.
Xu Y, Ren X, Jiang T, Lv S, Gao K, Liu Y, Yan Y.   +6 more
europepmc   +4 more sources

Evaluation of Isolation Methods for Circulating Tumor Cells (CTCs) [PDF]

Cellular Physiology and Biochemistry, 2016
Background: Detection of CTCs is a poor prognostic factor for many cancer types; however, their very low frequency represents an obstacle for their detection. The objective of the current study was to compare the performance of commonly used methods for CTCs isolation.
Galatea Kallergi, Eleni Politaki, Saad Alkahtani, Christos Stournaras, Vassilis Georgoulias   +4 more
openaire   +3 more sources

Fugitives on the run: circulating tumor cells (CTCs) in metastatic diseases. [PDF]

Cancer Metastasis Rev, 2019
The presence of circulating tumor cells (CTCs) in the bloodstream signals the existence of a tumor and denotes risk of metastatic spread. CTCs can be isolated and analyzed to monitor cancer progression and therapeutic response. However, CTC isolation devices have shown considerable variation in detection rates, limiting their use as a routine ...
Mamdouhi T, Twomey JD, McSweeney KM, Zhang B.   +3 more
europepmc   +4 more sources

The Prognostic Role of Circulating Tumor Cells (CTCs) in Lung Cancer. [PDF]

Front Oncol, 2018
Lung cancer affects over 1. 8 million people worldwide and is the leading cause of cancer related mortality globally. Currently, diagnosis of lung cancer involves a combination of imaging and invasive biopsies to confirm histopathology. Non-invasive diagnostic techniques under investigation include "liquid biopsies" through a simple blood draw to ...
Kapeleris J, Kulasinghe A, Warkiani ME, Vela I, Kenny L, O'Byrne K, Punyadeera C.   +6 more
europepmc   +8 more sources

Detection Methods and Clinical Applications of Circulating Tumor Cells in Breast Cancer

Frontiers in Oncology, 2021
Circulating Tumor Cells (CTCs) are cancer cells that split away from the primary tumor and appear in the circulatory system as singular units or clusters, which was first reported by Dr. Thomas Ashworth in 1869.
Hongyi Zhang, Xiaoyan Lin, Yuan Huang, Minghong Wang, Chunmei Cen, Shasha Tang, Marcia R. Dique, Lu Cai, Manuel A. Luis, Jillian Smollar, Yuan Wan, Fengfeng Cai   +11 more
doaj   +1 more source