Results 61 to 70 of about 5,745,790 (267)
Significance of Studying Circulating Tumor Cells
, 2016 Circulating Tumor Cells (CTC) are tumor cells released into blood. They are considered the pivotal component of the metastatic cascade and are being extensively studied only in the last decade or so.
Richard J. Cote +5 more
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
, 2020 The number of circulating tumor cells (CTCs) hase been found as a promising predictive and diagnostic biomarker of colorectal cancer (CRC). The purpose of the study was to enumerate and characterize CTCs from the CRC patients and evaluate the correlation
Cu-Tai Lu +13 more
core +1 more source
Single-cell analyses of circulating tumor cells
Cancer Biology & Medicine, 2015 Circulating tumor cells (CTCs) are a population of tumor cells mediating metastasis, which results in most of the cancer related deaths. The number of CTCs in the peripheral blood of patients is rare, and many platforms have been launched for detection ...
Xi-Xi Chen, Fan Bai
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Circulating tumor cells in pancreatic cancer: more than liquid biopsy
Therapeutic Advances in Medical OncologyCirculating tumor cells (CTCs) are tumor cells that slough off the primary lesions and extravasate into the bloodstream. By forming CTC clusters and interacting with other circulating cells (platelets, NK cells, macrophage, etc.), CTCs are able to ...
Zeru Li +6 more
doaj +1 more source
Circulating Tumor Cells: From the Laboratory to the Cancer Clinic
, 2020 Circulating tumor cells (CTCs) are cells that are separated from the primary tumor, move through the bloodstream, and spread from the original tumor to other sites, causing cancer metastasis [...
Noriyoshi Sawabata
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Recent Advances in Light‐Addressable Electrochemistry for Spatially Resolved Applications
Advanced Materials Technologies, EarlyView.This comprehensive review highlights light‐addressable electrochemistry as a powerful tool that uses light to control localized chemical reactions on unstructured semiconductor surfaces. The work evaluates advanced strategies to optimize electrode materials for enhanced spatial resolution and stability. Furthermore, it showcases diverse applications in
Nhi Trang Vo +2 more
wiley +1 more source
Cell Reports, 2020 Summary: During metastasis, cancer cells are exposed to potentially destructive hemodynamic forces including fluid shear stress (FSS) while en route to distant sites.
Devon L. Moose +12 more
doaj +1 more source