Results 61 to 70 of about 5,339,936 (244)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Cell Reports, 2020 Summary: During metastasis, cancer cells are exposed to potentially destructive hemodynamic forces including fluid shear stress (FSS) while en route to distant sites.
Devon L. Moose +12 more
doaj +1 more source
Significance of Studying Circulating Tumor Cells
, 2016 Circulating Tumor Cells (CTC) are tumor cells released into blood. They are considered the pivotal component of the metastatic cascade and are being extensively studied only in the last decade or so.
Richard J. Cote +5 more
core +1 more source
Radiomics and circulating tumor cells: personalized care in hepatocellular carcinoma? [PDF]
, 2015 Personalized care in oncology is expected to significantly improve morbidity and mortality, facilitated by our increasing understanding of the molecular mechanisms driving tumors and the ability to target those drivers.
Richard L. Hesketh +2 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Circulating tumor cells in pancreatic cancer: more than liquid biopsy
Therapeutic Advances in Medical OncologyCirculating tumor cells (CTCs) are tumor cells that slough off the primary lesions and extravasate into the bloodstream. By forming CTC clusters and interacting with other circulating cells (platelets, NK cells, macrophage, etc.), CTCs are able to ...
Zeru Li +6 more
doaj +1 more source
Research status of self-seeding by circulating tumor cells in tumor progression
Kouqiang hemian waike zazhiSelf-seeding, a distinct biological behavior of circulating tumor cells (CTCs), is prevalent in many malignant tumors and closely linked to tumor progression.
DAI Zhenlin, XU Qin
doaj +1 more source
APL Bioengineering, 2023 Tumor cells metastasize to distant organs mainly via hematogenous dissemination, in which circulating tumor cells (CTCs) are relatively vulnerable, and eliminating these cells has great potential to prevent metastasis. In vasculature, natural killer (NK)
Bing Hu +4 more
doaj +1 more source
Microfilter-Based Capture and Release of Viable Circulating Tumor Cells
, 2017 Microfilters with slot-pore geometry can be used for size-based capture of circulating tumor cells (CTC) from the blood of cancer patients. The slot pore geometry reduces the shear stress that the cells would typically experience during filtration ...
Siddarth Rawal +7 more
core +1 more source
The Prognostic Significance of Circulating Tumor Cells in Patients with Pancreatobiliary Cancer
, 2023 Background: Circulating tumor cells are cancer cells which separate from the primary tumor and enter systemic circulation. In this study, it was aimed to examine the relationship between circulating tumor cells isolated and identified from the peripheral
Başbınar, Yasemin +28 more
core +1 more source