Results 71 to 80 of about 5,745,790 (267)

Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D-mediated mechanosensing

open access: yesAPL Bioengineering, 2023
Tumor cells metastasize to distant organs mainly via hematogenous dissemination, in which circulating tumor cells (CTCs) are relatively vulnerable, and eliminating these cells has great potential to prevent metastasis. In vasculature, natural killer (NK)
Bing Hu   +4 more
doaj   +1 more source

Microfiltration Device For Circulating Tumor Cells Isolation (MEMS)-(CTCS)

open access: yesIngeniería Solidaria, 2023
Introduction: This document proposes the design and simulation of a microfilter device for the capture of circulating tumor cells, motivated by support for prevention and treatment methods against cancer, the objective of the proposal is the designed a device for separating cancer cells from blood fluid, with high efficiency.
Alan González, Carlos Borrás Pinilla
openaire   +1 more source

Integrated EpCAM‐independent subtraction enrichment and iFISH strategies to detect and classify disseminated and circulating tumors cells

open access: yesClinical and Translational Medicine, 2015
Application of tumor cell surface adhesion molecule EpCAM‐dependent antibody capture, and intracellular cytokeratins (CKs)‐dependent immunostaining strategies to detect disseminated or circulating tumor cells (DTCs or CTCs), is limited by highly ...
Peter Ping Lin
doaj   +1 more source

Microfilter-Based Capture and Release of Viable Circulating Tumor Cells

open access: yes, 2017
Microfilters with slot-pore geometry can be used for size-based capture of circulating tumor cells (CTC) from the blood of cancer patients. The slot pore geometry reduces the shear stress that the cells would typically experience during filtration ...
Siddarth Rawal   +7 more
core   +1 more source

Inorganic Nanomaterials can Promote or Inhibit Tumor Metastasis Depending on Tumor Microenvironment Composition

open access: yesAdvanced Science, EarlyView.
As engineered nanomaterials gain prominence in cancer imaging and therapy, understanding their impact on tumor progression becomes increasingly critical. We demonstrate that gold and silica‐coated gold nanomaterials can either suppress or enhance breast cancer metastasis through distinct tumor microenvironment interactions, while identifying ...
Kiana Buttiens   +11 more
wiley   +1 more source

A label-free microfluidic chip for the highly selective isolation of single and cluster CTCs from breast cancer patients

open access: yesTranslational Oncology, 2021
Background: Circulating tumor cells (CTCs) existing in peripheral blood can be used to predict the prognosis and survival of cancer patients. The study was designed to detect circulating tumor cells and circulating tumor single cell genes by applying ...
Xiaofen Zhang   +5 more
doaj   +1 more source

Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications

open access: yes, 2015
Stimulus responsive release of Circulating Tumor Cells (CTCs), with high recovery rates from their capture platform, is highly desirable for off-chip analyses.
Cote, Richard J   +9 more
core   +1 more source

Tumor Hypoxia and Circulating Tumor Cells

open access: yes, 2020
Circulating tumor cells (CTCs) are a rare tumor cell subpopulation induced and selected by the tumor microenvironment’s extreme conditions. Under hypoxia and starvation, these aggressive and invasive cells are able to invade the lymphatic and ...
Marco Durante   +5 more
core   +1 more source

Space Jam‐Ming: Generating Interstitial Space Using Fragmented Granular GelMA to Investigate Novel Paradigms of Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Microgels enable independent control of stiffness and interstitial space, overcoming limitations of conventional 3D hydrogels. Using fragmented gelatin methacryloyl microgels, we show that stiffness does not restrict non‐metastatic breast cancer growth, contrary to bulk hydrogels, and reveal the role of adherent‐to‐suspension transition in cancer ...
Danielle Vahala   +15 more
wiley   +1 more source

The role of extracellular vesicles in circulating tumor cell-mediated distant metastasis

open access: yesMolecular Cancer, 2023
Current research has demonstrated that extracellular vesicles (EVs) and circulating tumor cells (CTCs) are very closely related in the process of distant tumor metastasis.
Siyin Guo   +5 more
doaj   +1 more source

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