Results 71 to 80 of about 5,339,936 (244)

Electroactive 3D Porous Graphene Foam Impedimetric Biosensor for Ultrasensitive Detection of MCF‐7‐Cells‐Derived Extracellular Vesicles in Human Serum

Advanced Materials Technologies, EarlyView.
A label‐free impedimetric biosensor based on electroactive 3D porous graphene foam enables ultrasensitive and selective detection of CD81 protein and MCF‐7 cell‐derived extracellular vesicles in human serum. Detection limits of 0.048 fg/mL for CD81 and ∼24 EVs/mL are achieved, demonstrating a robust platform for selective, label‐free, and ...
Michael Robert Furness, Ashish Kalkal, Tia Wardlaw, Jessica Valli, Suresh Chandra Baral, Pablo Lozano Sanchez, Marco Caffio, Sudhagar Pitchaimuthu, Olga Oikonomidou, Jason Webber, Nick R. Leslie, Anitha Devadoss   +11 more
wiley   +1 more source

Natural killer cells: the immune frontline against circulating tumor cells

Journal of Experimental & Clinical Cancer Research
Natural killer (NK) play a key role in controlling tumor dissemination by mediating cytotoxicity towards cancer cells without the need of education. These cells are pivotal in eliminating circulating tumor cells (CTCs) from the bloodstream, thus limiting
Doryan Masmoudi, Martin Villalba, Catherine Alix-Panabières   +2 more
doaj   +1 more source

Integrated EpCAM‐independent subtraction enrichment and iFISH strategies to detect and classify disseminated and circulating tumors cells

Clinical and Translational Medicine, 2015
Application of tumor cell surface adhesion molecule EpCAM‐dependent antibody capture, and intracellular cytokeratins (CKs)‐dependent immunostaining strategies to detect disseminated or circulating tumor cells (DTCs or CTCs), is limited by highly ...
Peter Ping Lin
doaj   +1 more source

Case report: Post-therapeutic laryngeal carcinoma patient possessing a high ratio of aneuploid CTECs to CTCs rapidly developed de novo malignancy in pancreas

Frontiers in Oncology, 2022
Effectively evaluating therapeutic efficacy, detecting minimal residual disease (MRD) after therapy completion, and predicting early occurrence of malignancy in cancer patients remain as unmet imperative clinical demands.
Jiaoping Mi, Fang Yang, Jiani Liu, Mingyang Liu, Alexander Y. Lin, Daisy Dandan Wang, Peter Ping Lin, Qi Zeng   +7 more
doaj   +1 more source

Perspectives on the Functional Characterization and In Vitro Maintenance of Circulating Tumor Cells

, 2016
Circulating tumor cells (CTCs) that detach and migrate from primary tumors are implicated in the metastatic spread of cancer. The identification of CTCs in peripheral blood samples has been associated with poor survival outcomes in various cancer types ...
Harouaka, Ramdane, Ramdane Harouaka, Cote, Richard J, Richard Schlegel, Anthony Williams, Siyang Zheng, Ram H. Datar, Schlegel, Richard, Albanese, Chris, Cote, Richard J., Zheng, Siyang, Chris Albanese, Richard J. Cote, Yu-Chong Tai, Williams, Anthony, Tai, Yu-Chong, Datar, Ram H, Datar, Ram H.   +17 more
core   +1 more source

Microfiltration Device For Circulating Tumor Cells Isolation (MEMS)-(CTCS)

Ingeniería Solidaria, 2023
Introduction: This document proposes the design and simulation of a microfilter device for the capture of circulating tumor cells, motivated by support for prevention and treatment methods against cancer, the objective of the proposal is the designed a device for separating cancer cells from blood fluid, with high efficiency.
Alan González, Carlos Borrás Pinilla
openaire   +1 more source

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano, Allen C. Luo, Paul Taufalele, Jenna A. Dombroski, Ehsan Aalaei, Schyler J. Rowland, Melissa S. Cantú, Alexandria T. Carter, Samantha V. Knoblauch, Cynthia A. Reinhart‐King, Michael R. King   +10 more
wiley   +1 more source

A label-free microfluidic chip for the highly selective isolation of single and cluster CTCs from breast cancer patients

Translational Oncology, 2021
Background: Circulating tumor cells (CTCs) existing in peripheral blood can be used to predict the prognosis and survival of cancer patients. The study was designed to detect circulating tumor cells and circulating tumor single cell genes by applying ...
Xiaofen Zhang, Xu Lu, Wanlei Gao, Yanmin Wang, Chunping Jia, Hui Cong   +5 more
doaj   +1 more source

Current detection technologies for circulating tumor cells

, 2017
Circulating tumor cells (CTCs) are cancer cells that circulate in the blood stream after being naturally shed from original or metastatic tumors, and can lead to a new fatal metastasis.
Zheyu Shen, Aiguo Wu, Chen, Xiaoyuan, Wu, Aiguo, Xiaoyuan Chen, Shen, Zheyu   +5 more
core   +1 more source

A Novel tRNA Half mt‐5’‐tiRNA‐Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation

Advanced Science, EarlyView.
A mitochondria‐derived tRNA half, mt‐5’‐tiRNA‐Tyr, is upregulated in colorectal cancer tissues and plasma and promotes tumor proliferation. It binds HARS2 and promotes CPT1A‐associated HARS2 K91 succinylation, disrupts HARS2–mt‐tRNA‐His association, impairs mitochondrial translation, enhances succinate‐linked metabolic reprogramming, and shows promise ...
Xinliang Gu, Danping Zhu, Xinwei Liu, Shangshang Hu, Xincheng Yang, Junjie Nie, Tao Xu, Yuqin Pan, Mu Xu, Huiling Sun, Shukui Wang   +10 more
wiley   +1 more source