Results 31 to 40 of about 1,653,509 (288)

Circular RNAs Are Promising Biomarkers in Liquid Biopsy for the Diagnosis of Non-small Cell Lung Cancer

Frontiers in Molecular Biosciences, 2021
The high incidence and mortality of lung cancer make early detection of lung cancer particularly important. At present, the diagnosis of lung cancer mainly depends on diagnostic imaging and tissue biopsy. However, current diagnostics are not satisfactory
Lanxiang Huang, Lanxiang Huang, Yuan Rong, Yuan Rong, Xuan Tang, Xuan Tang, Kezhen Yi, Kezhen Yi, Jianyuan Wu, Fubing Wang, Fubing Wang, Fubing Wang   +11 more
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NGS‐based liquid biopsy profiling identifies mechanisms of resistance to ALK inhibitors: a step toward personalized NSCLC treatment

Molecular Oncology, 2021
Despite impressive and durable responses, nonsmall cell lung cancer (NSCLC) patients treated with anaplastic lymphoma kinase (ALK) inhibitors (ALK‐Is) ultimately progress due to development of resistance.
Estela Sánchez‐Herrero, Roberto Serna‐Blasco, Vadym Ivanchuk, Rosario García‐Campelo, Manuel Dómine Gómez, José M. Sánchez, Bartomeu Massutí, Noemi Reguart, Carlos Camps, Sandra Sanz‐Moreno, Silvia Calabuig‐Fariñas, Eloísa Jantus‐Lewintre, Magdalena Arnal, Dietmar Fernández‐Orth, Virginia Calvo, Víctor González‐Rumayor, Mariano Provencio, Atocha Romero   +17 more
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Elevated TEFM expression promotes growth and metastasis through activation of ROS/ERK signaling in hepatocellular carcinoma

Cell Death and Disease, 2021
TEFM (transcription elongation factor of mitochondria) has been identified as a novel nuclear-encoded transcription elongation factor in the transcription of mitochondrial genome.
Lixin Wan, Yang Wang, Zijie Zhang, Jiaxin Wang, Menglan Niu, Yuanyuan Wu, Yating Yang, Yongxia Dang, Shuang Hui, Meng Ni, Bo Wan, Dengke Bao   +11 more
doaj   +1 more source

Dynamic change of metabolic dysfunction-associated steatotic liver disease in chronic hepatitis C patients after viral eradication: A nationwide registry study in Taiwan [PDF]

Clinical and Molecular Hepatology
Background/Aims Steatotic liver disease (SLD) is a common manifestation in chronic hepatitis C (CHC). Metabolic alterations in CHC are associated with metabolic dysfunction-associated steatotic liver disease (MASLD).
Chung-Feng Huang, Chia-Yen Dai, Yi-Hung Lin, Chih-Wen Wang, Tyng-Yuan Jang, Po-Cheng Liang, Tzu-Chun Lin, Pei-Chien Tsai, Yu-Ju Wei, Ming-Lun Yeh, Ming-Yen Hsieh, Chao-Kuan Huang, Jee-Fu Huang, Wan-Long Chuang, Ming-Lung Yu   +14 more
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Report of results of pleural biopsy (Needle biopsy and open biopsy) in 108 cases and 245 biopsies [PDF]

, 1960
1. The results of 245 pleural biopsies perfomed in 108 patients including 219 pleural needle biopsies and 26 pleural open biopsies were reported. The method of pleural biopsy seems to be superior to any other currently available diagnostic procedures for
Sohn, Isaack, Mc, Lt. Col.
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Long noncoding RNA LINC00662 promotes M2 macrophage polarization and hepatocellular carcinoma progression via activating Wnt/β‐catenin signaling

Molecular Oncology, 2020
Tumor‐associated macrophages have important roles in hepatocellular carcinoma (HCC) initiation and progression. Long noncoding RNAs (lncRNAs) have also been reported to be involved in HCC. In this study, we explored how lncRNA LINC00662 may influence HCC
Xiaohui Tian, Yuanyuan Wu, Yating Yang, Jiaxin Wang, Menglan Niu, Shanjun Gao, Tao Qin, Dengke Bao   +7 more
doaj   +1 more source

Dynamic gene screening enabled identification of a 10-gene panel for early detection and progression assessment of gastric cancer

Computational and Structural Biotechnology Journal, 2023
Early diagnosis and progression assessment are critical for the timely detection and treatment of gastric cancer (GC) patients. Identification of diagnostic biomarkers for early detection of GC represents an unmet clinical need, and how these markers ...
Fei Long, Shuo Li, Yaqi Xu, Min Liu, Xuan Zhang, Junting Zhou, Yiyi Chen, Yuan Rong, Xiangyu Meng, Fubing Wang   +9 more
doaj   +1 more source

International society of liquid biopsy (ISLB) perspective on minimal requirements for ctDNA testing in solid tumors [PDF]

: Circulating tumor DNA (ctDNA) testing has transformed precision oncology by enabling the non-invasive detection of actionable mutations. To facilitate broader clinical adoption and improve testing accuracy, standardized quality criteria must be clearly
Shetty, Omshree, Farinas, Silvia Calabuig, Jantus-Lewintre, Eloisa, Rolfo, Christian, Heeke, Simon, Serrano, Maria Jose, Malapelle, Umberto, Pepe, Francesco, Hofman, Paul, Heitzer, Ellen, Nigita, Giovanni, Burnier, Julia V., Patton, Simon J., Gandara, David R., Venetis, Konstantinos, Fusco, Nicola, Cristofanilli, Massimo   +16 more
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Liquid Biopsy: Current advancements in clinical practice for bladder cancer [PDF]

Bladder cancer is the ninth most common malignancy worldwide, with two clinically distinct forms: non-muscle-invasive disease, characterized by high recurrence and excellent long-term survival, and muscle-invasive disease, associated with poorer outcomes.
Pastore AL, Caputo VF, Magliocchetti M, Busetto GM, Musone M, Di Lieto D, Fuschi A, Falabella R, Balsamo R, Ferro M, Lucarelli G, Bianchi R, Finati M, Amicuzi U, Crocetto F, Del Giudice F, Tammaro S, Terracciano D.   +17 more
core   +2 more sources

Cost-effectiveness analysis of capecitabine maintenance therapy plus best supportive care vs. best supportive care alone as first-line treatment of newly diagnosed metastatic nasopharyngeal carcinoma

Frontiers in Public Health, 2023
ObjectivesMaintenance therapy with capecitabine after induction chemotherapy for patients with newly diagnosed metastatic nasopharyngeal carcinoma (mNPC) has been confirmed to be effective.
Jiaqi Han, Xiaomeng Lan, Kun Tian, Xi Shen, Jinlan He, Nianyong Chen   +5 more
doaj   +1 more source