Results 51 to 60 of about 5,116,830 (334)

Exosomal Liquid Biopsy for the Early Detection of Gastric Cancer

JAMA Surgery
This case-control study investigates the clinical utility of exosome-based microRNA as a liquid biopsy biomarker for the early detection of gastric cancer.
Silei Sui, Caiming Xu, M. Kanda, Y. Okugawa, Y. Toiyama, Joon Oh Park, Hoon Hur, Song Cheol Kim, A. Taketomi, Yasuhiro Kodera, Xiang-Dong Cheng, Man Li, Ajay Goel   +12 more
semanticscholar   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Liquid Biopsies [PDF]

medizinische genetik, 2016
Zusammenfassung „Liquid Biopsy“ bezieht sich in der Onkologie auf die Untersuchung von zirkulierenden Tumorzellen (engl.: circulating tumor cells [CTCs]) oder zirkulierender Tumor-DNA (engl.: circulating tumor DNA [ctDNA]), um nicht invasiv aus dem peripheren Blut Charakteristika über das Tumorgenom von Krebspatienten zu erfassen.
Speicher, Michael R., Gerger, Armin, Hoefler, Gerald   +2 more
openaire   +2 more sources

Validation of a ctDNA-Based comprehensive genomic profiling panel (IST80 Plus) for advanced non-small cell lung cancer

The Journal of Liquid Biopsy
Circulating tumor DNA (ctDNA) profiling can complement tissue testing in advanced non-small-cell lung cancer (NSCLC), particularly when tissue is unavailable or unable to capture tumor heterogeneity.
Pilar Mediavilla-Medel, Roberto Serna-Blasco, Lucia Robado de Lope, Alejandro Rodríguez Festa, Claudia González Alcalde, Eva De la Torre-Capitan Matías, Natalia García-Simon, Ana San Martin-Doblado, Mariano Provencio, Atocha Romero   +9 more
doaj   +1 more source

Exosomal miRNA profile as complementary tool in the diagnostic and prediction of treatment response in localized breast cancer under neoadjuvant chemotherapy

Breast Cancer Research, 2019
Background Breast cancer patients under neoadjuvant chemotherapy includes a heterogeneous group of patients who eventually develop distal disease, not detectable by current methods.
Alba Rodríguez-Martínez, Diego de Miguel-Pérez, Francisco Gabriel Ortega, José Luis García-Puche, Inmaculada Robles-Fernández, José Exposito, Jordi Martorell-Marugan, Pedro Carmona-Sáez, María del Carmen Garrido-Navas, Christian Rolfo, Hugh Ilyine, José Antonio Lorente, Marta Legueren, María José Serrano   +13 more
doaj   +1 more source

Crucial roles of circulating tumor cells in the metastatic cascade and tumor immune escape: biology and clinical translation

Journal for ImmunoTherapy of Cancer, 2022
Cancer-related deaths are mainly caused by metastatic spread of tumor cells from the primary lesion to distant sites via the blood circulation.
Klaus Pantel, Catherine Alix-Panabières
doaj   +1 more source

Reporting of molecular test results from cell-free DNA analyses: expert consensus recommendations from the 2023 European Liquid Biopsy Society ctDNA Workshop

EBioMedicine
Summary The implementation of circulating tumor DNA (ctDNA) in the diagnostic routine may enable non-invasive predictive biomarker testing and treatment optimization in patients who lack a suitable tumor specimen, have failed previous molecular analysis ...
V. D. de Jager, P. Giacomini, J. Fairley, R. Toledo, Simon J. Patton, S. Joosse, Claudia Koch, Z. Deans, K. Pantel, Ellen Heitzer, Ed Schuuring   +10 more
semanticscholar   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Circulating Genetically Abnormal Cells Add Non-Invasive Diagnosis Value to Discriminate Lung Cancer in Patients With Pulmonary Nodules ≤10 mm

Frontiers in Oncology, 2021
BackgroundLung cancer screening using low-dose computed tomography (LDCT) often leads to unnecessary biopsy because of the low specificity among patients with pulmonary nodules ≤10 mm.
Maosong Ye, Xiaoxuan Zheng, Xiaoxuan Zheng, Xin Ye, Xin Ye, Xin Ye, Juncheng Zhang, Juncheng Zhang, Chuoji Huang, Chuoji Huang, Zilong Liu, Meng Huang, Meng Huang, Xianjun Fan, Xianjun Fan, Yanci Chen, Yanci Chen, Botao Xiao, Jiayuan Sun, Jiayuan Sun, Chunxue Bai   +20 more
doaj   +1 more source

Electrochemical liquid biopsy across cancer care pathway. [PDF]

J Liq Biopsy
Liquid biopsy has emerged as a powerful approach for tracking tumor dynamics through circulating biomarkers such as cell-free tumor DNA (ctDNA), circulating tumor cells (CTCs), extracellular vesicles (EVs), microRNAs (miRNAs) and soluble proteins. Unlike
Singh S, Raucci A, Miglione A, Kalligosfyri PM, Misso G, Caraglia M, Cocco S, De Laurentiis M, Giordano A, Cinti S.   +9 more
europepmc   +2 more sources