Results 241 to 250 of about 1,076,718 (296)

Bioinformatics and Data Analysis

, 2016
openaire   +2 more sources

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source

Key genes and associated mechanisms of PCOS and EC comorbidity: A bioinformatics analysis. [PDF]

Medicine (Baltimore)
Yao Y, Zhu S, Zhu X.
europepmc   +1 more source

GNL3 Orchestrates AR Transcriptional Programs to Drive Castration‐Resistant Prostate Cancer and Immune Evasion

Advanced Science, EarlyView.
GNL3 is a novel AR coregulator with dual coactivator and corepressor functions in prostate cancer (PCa). Our study uncovers a previously unrecognized mechanism by which the AR transcriptional complex integrates oncogenic signaling and immune suppression.
Cuiting Zhang, Tin Long Cheong, Nitin Narwade, Dandan Dong, Mokan Deng, Zhengqiang Miao, Zhaoqiang Ding, Wenchao Li, Kate Man Kei Lei, Gong‐Hong Wei, Terence Chuen Wai Poon, Chu‐Xia Deng, Edwin Cheung   +12 more
wiley   +1 more source

Autophagy related biomarkers in ulcerative colitis revealed by bioinformatics analysis and immune correlation. [PDF]

Sci Rep
Chen XX, Min S, Shen Z, Zhang M, Huang L, Su M, Shen H, Zhu L.   +7 more
europepmc   +1 more source

Integrated network pharmacology and comprehensive bioinformatics analysis to identify the mechanisms and molecular targets of ketamine in ischemic stroke-depression comorbidity. [PDF]

PLoS One
Shu Y, Guo Y, Xu S, He H, Zeng B, Yang Z, Gao W, Li J.   +7 more
europepmc   +1 more source

Ferroptosis in glaucoma: Identification of key genes NR1D2 and AKR1C3 based on transcriptome bioinformatics analysis. [PDF]

Medicine (Baltimore)
Hao W, Huang Z, Xu F, Zhao T, Zhang X.
europepmc   +1 more source

Identification of immune-related genes in diagnosing hypercholesterolemia with myocardial infarction through bioinformatics analysis. [PDF]

Front Immunol
Wu W, Peng Z, Yu Y, Lin Z, Zhang J, Lin M, Wu C, Xie Q.   +7 more
europepmc   +1 more source

Bioinformatics Analysis and Experimental Validation of ASF1B in Breast Tumors. [PDF]

Cancer Med
Xing W, Deng M, Wang W, Liu Y, Mi X, Li H, Ge X.   +6 more
europepmc   +1 more source