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Bioinformatics in Immunoglobulin Glycosylation Analysis

2021
Analytical methods developed for studying immunoglobulin glycosylation rely heavily on software tailored for this purpose. Many of these tools are now used in high-throughput settings, especially for the glycomic characterization of IgG. A collection of these tools, and the databases they rely on, are presented in this chapter.
Lisacek, Frédérique   +4 more
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Iatrogenic hypertension: a bioinformatic analysis

The Pharmacogenomics Journal, 2018
It is well known that a myriad of medications and substances can induce side effects that are related to blood pressure (BP) regulation. This study aims to investigate why certain drugs tend to cause iatrogenic hypertension (HTN) and focus on drug targets that are implicated in these conditions.Databases and resources such as SIDER, DrugBank, and ...
Alon, Botzer   +4 more
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RNA structure: bioinformatic analysis

Current Opinion in Microbiology, 2007
The range of functions ascribed to RNA molecules has grown considerably during recent years. Consequently, the analysis and comparison of RNA sequences have become recurrent tasks in molecular biology. Because the biological function of an RNA is expressed more by its folded architecture than by its sequence, original computational tools adapted to the
Jossinet, Fabrice   +2 more
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Bioinformatics Strategies for the Analysis of Lipids

2009
Owing to their importance in cellular physiology and pathology as well as to recent technological advances, the study of lipids has reemerged as a major research target. However, the structural diversity of lipids presents a number of analytical and informatics challenges.
Wheelock, Craig E.   +6 more
openaire   +2 more sources

Bioinformatics tools for secretome analysis

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013
Over recent years, analyses of secretomes (complete sets of secreted proteins) have been reported in various organisms, cell types, and pathologies and such studies are quickly gaining popularity. Fungi secrete enzymes can break down potential food sources; plant secreted proteins are primarily parts of the cell wall proteome; and human secreted ...
Dario, Caccia   +3 more
openaire   +2 more sources

Bioinformatics for Analysis of Poxvirus Genomes

2012
In recent years, there have been numerous unprecedented technological advances in the field of molecular biology; these include DNA sequencing, mass spectrometry of proteins, and microarray analysis of mRNA transcripts. Perhaps, however, it is the area of genomics, which has now generated the complete genome sequences of more than 100 poxviruses, that ...
Melissa, Da Silva, Chris, Upton
openaire   +2 more sources

Bioinformatics for Analysis of Poxvirus Genomes

2019
In recent years, there have been numerous technological advances in the field of molecular biology; these include next- and third-generation sequencing of DNA genomes and mRNA transcripts and mass spectrometry of proteins. Perhaps, however, it is genome sequencing that impacts a virologist the most.
Shin-Lin, Tu, Chris, Upton
openaire   +2 more sources

Bioinformatics Analysis for Interactive Proteomics

Current Protocols in Protein Science, 2005
AbstractHigh‐throughput protein‐protein interaction data are becoming a foundation for new biological discoveries. A major challenge is to manage, analyze, and model these data. In this unit several databases are described that are used to store, query, and visualize protein‐protein interaction data.
Yu, Chen, Dong, Xu
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Bioinformatic Analysis of Adhesion Proteins

2007
Proteins that mediate cell-cell and cell-extracellular matrix (ECM) adhesion have been fundamental in the evolution of multicellular animals. Fibrillar collagens, proteoglycans, integrins, and cadherins are present in all animals from sponges to mammals, and many other adhesion proteins have arisen during animal evolution. In general, adhesion proteins
Adams, Josephine C, Engel, Juergen
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Bioinformatics in protein analysis

2000
The chapter gives an overview of bioinformatic techniques of importance in protein analysis. These include database searches, sequence comparisons and structural predictions. Links to useful World Wide Web (WWW) pages are given in relation to each topic.
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