Results 311 to 320 of about 1,093,449 (328)
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Metabolomic Bioinformatic Analysis
2017Metabolomics allows for the investigation of the small molecules found within living systems. Based on the design of the experiments, it is not uncommon for these analyses to include matrices of thousands of variables. In order to handle such large datasets, many have turned to multivariate statistical analyses to analyze and understand their data ...
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Bioinformatics Analysis of Microarray Data
2009Gene expression profiling provides unprecedented opportunities to study patterns of gene expression regulation, for example, in diseases or developmental processes. Bioinformatics analysis plays an important part of processing the information embedded in large-scale expression profiling studies and for laying the foundation for biological ...
Yunyu, Zhang +2 more
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Bioinformatics/Biostatistics: Microarray Analysis
2011The quantity and complexity of the molecular-level data generated in both research and clinical settings require the use of sophisticated, powerful computational interpretation techniques. It is for this reason that bioinformatic analysis of complex molecular profiling data has become a fundamental technology in the development of personalized medicine.
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Bioinformatics in protein analysis
2000The chapter gives an overview of bioinformatic techniques of importance in protein analysis. These include database searches, sequence comparisons and structural predictions. Links to useful World Wide Web (WWW) pages are given in relation to each topic.
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Bioinformatic Analysis of Adhesion Proteins
2007Proteins that mediate cell-cell and cell-extracellular matrix (ECM) adhesion have been fundamental in the evolution of multicellular animals. Fibrillar collagens, proteoglycans, integrins, and cadherins are present in all animals from sponges to mammals, and many other adhesion proteins have arisen during animal evolution. In general, adhesion proteins
Adams, Josephine C, Engel, Juergen
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Bioinformatic Analysis of Circular RNA Expression
2021Circular RNAs (circRNAs) are stable RNA molecules generated by backsplicing that play regulatory functions through interaction with other RNA and proteins, as well as by encoding peptides. Dysregulation of circRNA expression can drive cancer development and progression with different mechanisms.
Gaffo E. +3 more
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Ontology-based resources for bioinformatics analysis
International Journal of Metadata, Semantics and Ontologies, 2011A number of specific web accessible databases are developed in order to shed light into biomolecular data, providing novel perspectives about particular scientific problems or presenting innovative data integration approaches. Ontologies constitute an important enhancement, since they allow a better representation of biological data, by providing a ...
Viti Federica +6 more
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Automated Tissue Analysis – a Bioinformatics Perspective
Methods of Information in Medicine, 2005Summary Objectives: Recent progress in automated tissue analysis (tissomics) provides reproducible phenotypical characterization of histological specimens. We introduce informatics tools to cluster and correlate quantitative tissue profiles with gene expression data.
A, Kriete, K, Boyce
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Bioinformatics Analysis: Gene Fusion
2008Gene fusion is an important evolutionary phenomenon. Human fusion proteins consisting of two or more fusion partners of bacterial origin exhibit accreted (enhanced or novel) function. These proteins mimic operons, simulate protein subunit interfaces in bacteria, exhibit multiple functions, and show alternative splicing in humans.
Meena Kishore Sakharkar +2 more
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Bioinformatic Analysis of Peptide Precursor Proteins
Annals of the New York Academy of Sciences, 2005Abstract: Neuropeptides are among the most important signal molecules in animals. Traditional identification of peptide hormones through peptide purification is a tedious and time‐consuming process. With the advent of the genome sequencing projects, putative peptide precursor can be mined from the genome.
G, Baggerman +3 more
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