Results 31 to 40 of about 5,714 (206)

3D Bioprinted Breast Cancer‐Stroma Model with Tailored Migration‐Permissive Bioink Reveals Impact of Adipose‐Derived Stromal Cells on Cancer Cell Migration and Invasion Dynamics

Advanced Healthcare Materials, EarlyView.
A migration‐permissive bioink composed of methacrylated collagen type I and thiolated hyaluronic acid enables 3D bioprinting of breast cancer‐stroma models. Single‐cell tracking reveals that adipose stromal cells enhance tumor cell motility and stromal invasion, accompanied by collagen remodeling, and a shift in tumor cell morphology.
Sabrina Stecher, Joachim Schenk, Alessandro Cianciosi, Katherina Hemmen, David Böhringer, Franziska Dusi, Jessica Faber, Philipp Stahlhut, Benedikt Gantert, Emilie Rouenhoff, Annika Gmöhling, Tessa Lühmann, Jörg Teßmar, Jürgen Groll, Silvia Budday, Tomasz Jüngst, Ben Fabry, Katrin G. Heinze, Petra Bauer‐Kreisel, Torsten Blunk   +19 more
wiley   +1 more source

Bioprinting High‐Cell‐Density Cardiac Tissue Constructs With Sustained Contractile Function

Advanced Healthcare Materials, EarlyView.
Contractile cardiomyocytes in 3D culture provide insights into the behavior of the heart. Combining a 3D bioprinting approach with a multi‐electrode array allows the development of the 3D culture to be monitored over time, and matured cultures allow the effect of drugs on cardiac function to be modelled, replicating effects seen in clinical application.
Priscila Melo, Wing Tai Tung, Harvey Lewis, Kavin Hettiarachchilage, Babis Tzivelekis, Rolando Berlinguer‐Palmini, Ana Marina Ferreira, Jason Gill, Kenneth Dalgarno   +8 more
wiley   +1 more source

Meniscus‐Guided Interfacial Ring‐by‐Ring Assembly for In Situ Fabrication of Tubular Hydrogels

Advanced Materials, EarlyView.
A tubular hydrogel fabrication method leveraging the meniscus effect at the oil‐water interface is presented. UV irradiation across the concave surface of the photocurable hydrogel precursor induces the formation of ring‐like hydrogel structures. Sequential ring‐by‐ring assembly within microchannels enables the construction of arteriole‐scale hydrogel ...
Yuki Kamiya, Yingzhe Wang, Keisuke Morishima   +2 more
wiley   +1 more source

Extrusion of Cell Encapsulated in Boron Nitride Nanotubes Reinforced Gelatin—Alginate Bioink for 3D Bioprinting

Gels, 2022
Three-dimensional (3D) bioprinting, an innovative technology, has gained the attention of researchers as a promising technique for the redevelopment of complex tissue or organ structures.
Akesh Babu Kakarla, Ing Kong, Cin Kong, Helen Irving, Colleen J. Thomas   +4 more
doaj   +1 more source

De Novo Autogenic Engineered Living Functional Materials

Advanced Materials, EarlyView.
A versatile platform for de novo autogenic engineered living materials is presented, leveraging protein mining, computational modeling, and synthetic biology. By reprogramming the Escherichia coli curli machinery with β‐solenoid proteins from non‐model bacteria, macroscopic biomaterials with enhanced mechanical properties, UV‐C irradiation protection ...
Hoda M. Hammad, Seth Swarnadeep, Erin C. Jackson, Nicolas Burns, Hongyu Wang, Harrison Priode, Robert B. Moore, Sanket Deshmukh, Avinash Manjula‐Basavanna, Anna M. Duraj‐Thatte   +9 more
wiley   +1 more source

Wound and Skin Healing in Space: The 3D Bioprinting Perspective

Frontiers in Bioengineering and Biotechnology, 2021
Skin wound healing is known to be impaired in space. As skin is the tissue mostly at risk to become injured during manned space missions, there is the need for a better understanding of the biological mechanisms behind the reduced wound healing capacity ...
Nieves Cubo-Mateo, Nieves Cubo-Mateo, Michael Gelinsky   +2 more
doaj   +1 more source

Nanocellulose Reinforced Hyaluronan-Based Bioinks

Biomacromolecules, 2023
Bioprinting of hydrogel-based bioinks can allow for the fabrication of elaborate, cell-laden 3D structures. In addition to providing an adequate extracellular matrix mimetic environment and high cell viability, the hydrogels must offer facile extrusion through the printing nozzle and retain the shape of the printed structure.
Andrea Träger, Sajjad Naeimipour, Michael Jury, Robert Selegård, Daniel Aili   +4 more
openaire   +3 more sources

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

Advanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger, Johann Schorzmann, Hsuan‐Heng Lu, Muhammad Osama, Julian Bauer, Michael Haug, Oliver Friedrich, Aldo R. Boccaccini, Frank Döpper, Sahar Salehi   +9 more
wiley   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

The impact of mechanical tuning on the printability of decellularized amniotic membrane bioinks for cell-laden bioprinting of soft tissue constructs

Scientific Reports
Decellularized extracellular matrix (dECM) bioinks hold significant potential in the 3D bioprinting of tissue-engineered constructs (TECs). While 3D bioprinting allows for the creation of custom-designed TECs, the development of bioinks based solely on ...
Golara Kafili, Elnaz Tamjid, Abdolreza Simchi   +2 more
doaj   +1 more source