Results 11 to 20 of about 175,608 (207)

Biologia molecular dos meningiomas

JBNC - JORNAL BRASILEIRO DE NEUROCIRURGIA, 2018
Meningiomas são tumores benignos que, algumas vezes, podem comportar-se de modo agressivo e/ou recorrente. Até o momento não há marcadores clínicos ou laboratoriais fidedignos que possam predizer como esta neoplasia evoluirá. Dessa forma, faz-se necessário o desenvolvimento de uma alternativa efetiva de tratamento quando não for possível a ressecção ...
Pedro Augustto de Santana Júnior, Suely K. Nagahashi Marie, Paulo Henrique Pires De Aguiar   +2 more
openaire   +2 more sources

In silico predicted epitopes from the COOH-terminal extension of cysteine proteinase B inducing distinct immune responses during Leishmania (Leishmania) amazonensis experimental murine infection [PDF]

, 2011
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular e Doenças Endêmicas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular e Doenças Endêmicas.
Bernardo AS Pereira, Franklin S Silva, Karina M Rebello, Marcel Marín-Villa, Yara M Traub-Cseko, Thereza CB Andrade, Álvaro L Bertho, Ernesto R Caffarena, Carlos R Alves   +8 more
core   +2 more sources

Lipid dynamics at dendritic spines

Frontiers in Neuroanatomy, 2014
Dynamic changes in the structure and composition of the membrane protrusions forming dendritic spines underlie memory and learning processes. In recent years a great effort has been made to characterize in detail the protein machinery that controls spine
Carlos Gerardo Dotti, Jose Antonio Esteban, Maria Dolores eLedesma   +2 more
doaj   +1 more source

Ser or Leu: Structural Snapshots of Mistranslation in Candida albicans

Frontiers in Molecular Biosciences, 2014
Candida albicans is a polymorphic opportunistic fungal pathogen normally residing as commensal on mucosal surfaces, skin and gastrointestinal and genitourinary tracts. However, in immunocompromised patients C.
Zsuzsa eSarkany, Alexandra eSilva, Pedro José Barbosa Pereira, Sandra eMacedo-Ribeiro   +3 more
doaj   +1 more source

Trinucleotide Repeats: A structural perspective

Frontiers in Neurology, 2013
Trinucleotide repeat (TNR) expansions are present in a wide range of genes involved in several neurological disorders, being directly involved in the molecular mechanisms underlying pathogenesis through modulation of gene expression and/or the function ...
Bruno eAlmeida, Sara eFernandes, Isabel A. Abreu, Sandra eMacedo-Ribeiro   +3 more
doaj   +1 more source

Resveratrol Administration Increases Transthyretin Protein Levels, Ameliorating AD Features: The Importance of Transthyretin Tetrameric Stability

Molecular Medicine, 2016
Previous in vivo work showed that resveratrol has beneficial effects in Alzheimer’s disease (AD) pathology, resulting in increased expression of transthyretin (TTR).
Luís Miguel Santos, Daniela Rodrigues, Mobina Alemi, Sara Costa Silva, Carlos Alexandre Ribeiro, Isabel Cardoso   +5 more
doaj   +1 more source

Functional Insights From KpfR, a New Transcriptional Regulator of Fimbrial Expression That Is Crucial for Klebsiella pneumoniae Pathogenicity

Frontiers in Microbiology, 2021
Although originally known as an opportunistic pathogen, Klebsiella pneumoniae has been considered a worldwide health threat nowadays due to the emergence of hypervirulent and antibiotic-resistant strains capable of causing severe infections not only on ...
Ana Érika Inácio Gomes, Thaisy Pacheco, Cristiane da Silva dos Santos, José Aires Pereira, Marcelo Lima Ribeiro, Michelle Darrieux, Lúcio Fábio Caldas Ferraz   +6 more
doaj   +1 more source

How Listeria monocytogenes organizes its surface for virulence

Frontiers in Cellular and Infection Microbiology, 2014
Listeria monocytogenes is a Gram-positive pathogen responsible for the manifestation of human listeriosis, an opportunistic foodborne disease with an associated high mortality rate.
Filipe eCarvalho, Sandra eSousa, Didier eCabanes   +2 more
doaj   +1 more source

Laboratório de Bioquímica e Biologia Molecular - LBBM

BEPA. Boletim Epidemiológico Paulista, 2023
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Roseli Tuan, Ana Maria Ribeiro Castro Duarte, José Eduardo Bracco, Adriano Pinter   +3 more
openaire   +1 more source

Centrosome polarization in T cells: a task for formins

Frontiers in Immunology, 2013
T-cell antigen receptor (TCR) engagement triggers the rapid reorientation of the centrosome, which is associated with the secretory machinery, towards the immunological synapse (IS) for polarized protein trafficking.
Laura eAndrés-Delgado, Olga Maria Antón, Miguel Angel Alonso   +2 more
doaj   +1 more source