Results 11 to 20 of about 55,587 (249)

The identification of the Rosa S-locus and implications on the evolution of the Rosaceae gametophytic self-incompatibility systems

Scientific Reports, 2021
In Rosaceae species, two gametophytic self-incompatibility (GSI) mechanisms are described, the Prunus self-recognition system and the Maleae (Malus/Pyrus/Sorbus) non-self- recognition system.
J. Vieira, J. Pimenta, A. Gomes, J. Laia, S. Rocha, P. Heitzler, C. P. Vieira   +6 more
doaj   +1 more source

Retroperitoneal white adipose tissue lipoprotein lipase activity is rapidly down-regulated in response to acute stress

Journal of Lipid Research, 2007
Tissue-specific regulation of LPL has been widely studied in rats. Previous studies reported that in vivo administration of adrenaline and acute stress cause an increase in plasma LPL activity coinciding with a decrease in white adipose tissue (WAT) LPL ...
Albert Casanovas, Núria Parramon, Ferran de la Cruz, Olga Andrés, José Terencio, M. Dolores López-Tejero, Miquel Llobera   +6 more
doaj   +1 more source

Biologia molecular dos meningiomas

JBNC - JORNAL BRASILEIRO DE NEUROCIRURGIA, 2018
Meningiomas são tumores benignos que, algumas vezes, podem comportar-se de modo agressivo e/ou recorrente. Até o momento não há marcadores clínicos ou laboratoriais fidedignos que possam predizer como esta neoplasia evoluirá. Dessa forma, faz-se necessário o desenvolvimento de uma alternativa efetiva de tratamento quando não for possível a ressecção ...
Pedro Augustto de Santana Júnior, Suely K. Nagahashi Marie, Paulo Henrique Pires De Aguiar   +2 more
openaire   +2 more sources

Lipid dynamics at dendritic spines

Frontiers in Neuroanatomy, 2014
Dynamic changes in the structure and composition of the membrane protrusions forming dendritic spines underlie memory and learning processes. In recent years a great effort has been made to characterize in detail the protein machinery that controls spine
Carlos Gerardo Dotti, Jose Antonio Esteban, Maria Dolores eLedesma   +2 more
doaj   +1 more source

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

Hepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo, Ivana Nikolic, Alfonso Mora, Elena Rodríguez, Luis Leiva‐Vega, Aránzazu Pintor‐Chocano, Daniel Horrillo, Lourdes Hernández‐Cosido, Jorge L. Torres, Eva Novoa, Rubén Nogueiras, Gema Medina‐Gómez, Miguel Marcos, Magdalena Leiva, Guadalupe Sabio   +14 more
wiley   +1 more source

Ser or Leu: Structural Snapshots of Mistranslation in Candida albicans

Frontiers in Molecular Biosciences, 2014
Candida albicans is a polymorphic opportunistic fungal pathogen normally residing as commensal on mucosal surfaces, skin and gastrointestinal and genitourinary tracts. However, in immunocompromised patients C.
Zsuzsa eSarkany, Alexandra eSilva, Pedro José Barbosa Pereira, Sandra eMacedo-Ribeiro   +3 more
doaj   +1 more source

Trinucleotide Repeats: A structural perspective

Frontiers in Neurology, 2013
Trinucleotide repeat (TNR) expansions are present in a wide range of genes involved in several neurological disorders, being directly involved in the molecular mechanisms underlying pathogenesis through modulation of gene expression and/or the function ...
Bruno eAlmeida, Sara eFernandes, Isabel A. Abreu, Sandra eMacedo-Ribeiro   +3 more
doaj   +1 more source

Biologia Molecular e Forense no Ensino Médio

Research, Society and Development, 2021
As dificuldades em biologia molecular desafiam os professores a buscarem novas metodologias de ensino. Sendo assim o presente estudo pretendeu desenvolver uma Sequência de Ensino Investigativa (SEI) com práticas de biologia molecular como ferramenta problematizadora para o ensino da genética forense.
Thâmara Chaves Cardoso, Michelle Mara de Oliveira Lima, Josiane Silva Araújo, Wellinton Santos Alves, Francielle Alline Martins, Pedro Marcos de Almeida   +5 more
openaire   +2 more sources

Resveratrol Administration Increases Transthyretin Protein Levels, Ameliorating AD Features: The Importance of Transthyretin Tetrameric Stability

Molecular Medicine, 2016
Previous in vivo work showed that resveratrol has beneficial effects in Alzheimer’s disease (AD) pathology, resulting in increased expression of transthyretin (TTR).
Luís Miguel Santos, Daniela Rodrigues, Mobina Alemi, Sara Costa Silva, Carlos Alexandre Ribeiro, Isabel Cardoso   +5 more
doaj   +1 more source

Functional Insights From KpfR, a New Transcriptional Regulator of Fimbrial Expression That Is Crucial for Klebsiella pneumoniae Pathogenicity

Frontiers in Microbiology, 2021
Although originally known as an opportunistic pathogen, Klebsiella pneumoniae has been considered a worldwide health threat nowadays due to the emergence of hypervirulent and antibiotic-resistant strains capable of causing severe infections not only on ...
Ana Érika Inácio Gomes, Thaisy Pacheco, Cristiane da Silva dos Santos, José Aires Pereira, Marcelo Lima Ribeiro, Michelle Darrieux, Lúcio Fábio Caldas Ferraz   +6 more
doaj   +1 more source