Results 191 to 200 of about 302,285 (314)

Dose tapering and treatment de-escalation of biologic therapies in chronic rhinosinusitis with nasal polyps: a narrative review. [PDF]

Front Surg
AlSharhan SS, Aljubran HJ.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Correction to "Paradigm Guiding to Tapering or Discontinuation of Biologic and Targeted Synthetic Disease-Modifying Antirheumatic Drugs in the Treatment of Patients With Rheumatoid Arthritis: Results From a Local Retrospective Cohort Study". [PDF]

Int J Rheum Dis
europepmc   +1 more source

Efficacy and safety of ovine reinforced tissue matrix for ventral hernia repair: a systematic review and meta-analysis. [PDF]

Hernia
Lima DL, Morais MC, Graziani E Sousa A, da Silva de Almeida LM, Graciolli L, Parra-Davila E, Morales-Conde S, Malcher F.   +7 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Clinical practice guideline for psoriasis management in Latin America. [PDF]

An Bras Dermatol
Valenzuela F, Castro Ayarza JR, Kaplan D, Londoño-García AM, Macías García KDR, Magariños G, Rivas Záldivar ES, Franco M, Cano S, Cortés C, Cárdenas PJ, Castro C, Ferreira R, Martínez S, Ibatá Bernal L, Castillo JC, Ospina J.   +16 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Impact of Prior Biologic Exposure on Upadacitinib Efficacy in Inflammatory Bowel Disease: A Systematic Review of Randomized Controlled Trials. [PDF]

Cureus
Htun M, Lilhori A, Alamgir M, Al-Shemary M, Sriram R, Azeez N, Rajbhandari P, Muratova A, Patil S, Godavarthy PK, Mahmood A, Kylanathan J, Teli A.   +12 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Biologic Therapy Is Associated with Reduced Pleural-Line Thickness in Severe Asthma: A Prospective Transthoracic Ultrasound Study. [PDF]

J Clin Med
Erbay M, Akkaya S, Öztuna F, Tayar H.
europepmc   +1 more source