Results 171 to 180 of about 302,285 (314)

Short-term Outcomes of Polydioxanone Synthetic Mesh in 2-stage Breast Reconstruction: A Single-Center Comparative Study. [PDF]

Aesthet Surg J
Abbott EN, Li R, King D, Chumakov PE, Dash E, Kubiak CA, Braun SA, Gabriel A, Vucovich M, Mioton LM, Perdikis G.   +10 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Proactive Tight Monitoring of Patients with Inflammatory Bowel Disease in Biological Therapy: A Controlled Clinical Study (TIME IT). [PDF]

J Clin Med
Christensen KR, Al-Obaidi OSA, Buhl S, Ilvemark JF, Steenholdt C, Brynskov J, Ainsworth MA.   +6 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Pediatric spontaneous-reporting patterns for biologics approved or used for asthma: Analysis of the FDA adverse event reporting system. [PDF]

Pediatr Allergy Immunol
Zhang Y, Liu Y, Chen L, Chen Y, Zheng X.
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Patient Preferences in Hidradenitis Suppurativa Depend on Treatment Experience: Results from APProach-HS

Patient Preference and Adherence
Christian Kromer,1 Kristin Faverio,2,3 Tatiana Görig,4 Sylke Schneider-Burrus,5 Friderike Benzel,2 Matthias Goebeler,6 Dagmar Presser,6 Patrick Schummer,6 Marthe-Lisa Schaarschmidt,7 Wolfgang Harth,8 Rotraut Mössner,1,* Wiebke K Peitsch2,*
Kromer C, Faverio K, Görig T, Schneider-Burrus S, Benzel F, Goebeler M, Presser D, Schummer P, Schaarschmidt ML, Harth W, Mössner R, Peitsch WK   +11 more
doaj  

Incidence of New Malignancies in Severe Asthma: Comparison of Real-World Patients Treated with Benralizumab, Other Biologics, or Non-biologics. [PDF]

Pulm Ther
Dareng EO, Tran TN, Urbanski H, Finch R, Emerath U, Kurdyukova Y, Jison ML, Bahadori L, Menzies-Gow A, Wang E, Bel EH, de Llano LP, Emmanuel B, Olinger L.   +13 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source