Results 151 to 160 of about 310,970 (312)
Table_9_Association between pre-biologic T2-Biomaker combinations and response to biologics in patients with severe asthma.docx
BackgroundTo date, studies investigating the association between pre-biologic biomarker levels and post-biologic outcomes have been limited to single biomarkers and assessment of biologic efficacy from structured clinical trials.AimTo elucidate the ...Sinthia Z. Bosnic-Anticevich (18408009), Ruth B. Murray (9263969), Andrew N. Menzies-Gow (18408036), George C. Christoff (18408000), Christian Taube (35629), Ivan Solarte (18408048), Laura Pini (10969333), Tze Lee Tan (18408066), Sundeep Salvi (804859), Luisa Brussino (6617354), Eve Denton (18408024), Carlos A. Torres-Duque (11136750), Richard B. Hubbard (7777829), Bassam Mahboub (7362143), Giorgio Walter Canonica (7382129), Rita Amaral (5173736), Lauri Lehtimäki (689957), Trung N. Tran (5559110), Mei Fong Liew (10909834), John Townend (118565), Joao A. Fonseca (18408027), Eileen Wang (4471834), Camille Taillé (829699), Celeste M. Porsbjerg (9263975), Borja G. Cosio (3184737), Diahn-Warng Perng (Steve) (18408060), Alan Altraja (74156), Mark Hew (3203178), Tatsuya Nagano (636701), Guy G. Brusselle (7634108), Celine Bergeron (18407997), Désirée Larenas-Linnemann (12113454), David B. Price (3133764), David J. Jackson (4405432), Mona Al-Ahmad (12040516), Lakmini Bulathsinhala (3663172), Chau-Chyun Sheu (524362), Chin Kook Rhee (7492325), Kirsty Fletton (18408015), Enrico Heffler (6617369), Leif Bjermer (3291531), Bellanid Rodríguez-Cáceres (18408045), Stefania Nicola (6851225), Agnieszka Ławkiedraj (18408033), Neil Martin (73632), Luis Perez-De-Llano (18408042), John Busby (3509471), Mohsen Sadatsafavi (63962), John Abisheganaden (14581367), Nikolaos G. Papadopoulos (7677542), Tunn Ren Tay (3203172), Gregory P. Katsoulotos (18408003), Flavia Hoyte (18408030), Ming-Ju Tsai (770331), Michael E. Wechsler (7923218), Martina Zappa (18408051), Susanne Hansen (323324), Liam G. Heaney (7754321), Victoria Carter (232149), Jorge Máspero (18408057), Aaron Beastall (18408012), Peter G. Gibson (8250825), Wenjia Chen (844791), Li Ping Chung (18408021), Konstantinos Kostikas (361271), Charlotte Suppli Ulrik (7757765), Richard W. Costello (7934465), Riyad Al-Lehebi (18408006), Piotr Kuna (3549902), Arnaud Bourdin (376853), Takashi Iwanaga (2166256), Libardo Jiménez-Maldonado (18408069), Concetta Sirena (18408063), Paul E. Pfeffer (4984613), Bruce J. Kirenga (8823890), Pee Hwee Pang (7724246), Matthew J. Peters (8781407), Francesca Puggioni (6851219), Todor A. Popov (7583747), Pujan H. Patel (18408039), Luisa Ricciardi (12532573), Rohit Katial (12542123), Andriana I. Papaioannou (13531845), Diana Jimena Cano Rosales (18408018), Karin Dahl Assing (18408054), Florence Schleich (394436), Mariko Siyue Koh (9295747) +86 morecore +1 more sourceHealth utility by Psoriasis Area and Severity Index response status after biologic induction therapy in Chinese patients with moderate to severe psoriasis
Journal of Comparative Effectiveness ResearchAim: Psoriasis severely affects quality of life, particularly in patients with moderate to severe psoriasis.
This study aims to estimate health utility by Psoriasis Area and Severity Index (PASI) response after
biologic induction therapy in Chinese ...Lu Jian, Liang Zhang, Guo Zhou, Xingzhi Wang, Kun Hu, Yongfang Duan, Mi Zhang, Liang Tan, Wendong Chen, Bingfa Li, Yehong Kuang +10 moredoaj +1 more sourceThe ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...Destiny Davis, Lesly Mejia, Emily K Moser +2 morewiley +1 more sourceTable_8_Association between pre-biologic T2-Biomaker combinations and response to biologics in patients with severe asthma.docx
BackgroundTo date, studies investigating the association between pre-biologic biomarker levels and post-biologic outcomes have been limited to single biomarkers and assessment of biologic efficacy from structured clinical trials.AimTo elucidate the ...Sinthia Z. Bosnic-Anticevich (18408009), Ruth B. Murray (9263969), Andrew N. Menzies-Gow (18408036), George C. Christoff (18408000), Christian Taube (35629), Ivan Solarte (18408048), Laura Pini (10969333), Tze Lee Tan (18408066), Sundeep Salvi (804859), Luisa Brussino (6617354), Eve Denton (18408024), Carlos A. Torres-Duque (11136750), Richard B. Hubbard (7777829), Bassam Mahboub (7362143), Giorgio Walter Canonica (7382129), Rita Amaral (5173736), Lauri Lehtimäki (689957), Trung N. Tran (5559110), Mei Fong Liew (10909834), John Townend (118565), Joao A. Fonseca (18408027), Eileen Wang (4471834), Camille Taillé (829699), Celeste M. Porsbjerg (9263975), Borja G. Cosio (3184737), Diahn-Warng Perng (Steve) (18408060), Alan Altraja (74156), Mark Hew (3203178), Tatsuya Nagano (636701), Guy G. Brusselle (7634108), Celine Bergeron (18407997), Désirée Larenas-Linnemann (12113454), David B. Price (3133764), David J. Jackson (4405432), Mona Al-Ahmad (12040516), Lakmini Bulathsinhala (3663172), Chau-Chyun Sheu (524362), Chin Kook Rhee (7492325), Kirsty Fletton (18408015), Enrico Heffler (6617369), Leif Bjermer (3291531), Bellanid Rodríguez-Cáceres (18408045), Stefania Nicola (6851225), Agnieszka Ławkiedraj (18408033), Neil Martin (73632), Luis Perez-De-Llano (18408042), John Busby (3509471), Mohsen Sadatsafavi (63962), John Abisheganaden (14581367), Nikolaos G. Papadopoulos (7677542), Tunn Ren Tay (3203172), Gregory P. Katsoulotos (18408003), Flavia Hoyte (18408030), Ming-Ju Tsai (770331), Michael E. Wechsler (7923218), Martina Zappa (18408051), Susanne Hansen (323324), Liam G. Heaney (7754321), Victoria Carter (232149), Jorge Máspero (18408057), Aaron Beastall (18408012), Peter G. Gibson (8250825), Wenjia Chen (844791), Li Ping Chung (18408021), Konstantinos Kostikas (361271), Charlotte Suppli Ulrik (7757765), Richard W. Costello (7934465), Riyad Al-Lehebi (18408006), Piotr Kuna (3549902), Arnaud Bourdin (376853), Takashi Iwanaga (2166256), Libardo Jiménez-Maldonado (18408069), Concetta Sirena (18408063), Paul E. Pfeffer (4984613), Bruce J. Kirenga (8823890), Pee Hwee Pang (7724246), Matthew J. Peters (8781407), Francesca Puggioni (6851219), Todor A. Popov (7583747), Pujan H. Patel (18408039), Luisa Ricciardi (12532573), Rohit Katial (12542123), Andriana I. Papaioannou (13531845), Diana Jimena Cano Rosales (18408018), Karin Dahl Assing (18408054), Florence Schleich (394436), Mariko Siyue Koh (9295747) +86 morecore +1 more sourceMetastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano +2 morewiley +1 more sourceImage_1_Association between pre-biologic T2-Biomaker combinations and response to biologics in patients with severe asthma.pdf
BackgroundTo date, studies investigating the association between pre-biologic biomarker levels and post-biologic outcomes have been limited to single biomarkers and assessment of biologic efficacy from structured clinical trials.AimTo elucidate the ...Sinthia Z. Bosnic-Anticevich (18408009), Ruth B. Murray (9263969), Andrew N. Menzies-Gow (18408036), George C. Christoff (18408000), Christian Taube (35629), Ivan Solarte (18408048), Laura Pini (10969333), Tze Lee Tan (18408066), Sundeep Salvi (804859), Luisa Brussino (6617354), Eve Denton (18408024), Carlos A. Torres-Duque (11136750), Richard B. Hubbard (7777829), Bassam Mahboub (7362143), Giorgio Walter Canonica (7382129), Rita Amaral (5173736), Lauri Lehtimäki (689957), Trung N. Tran (5559110), Mei Fong Liew (10909834), John Townend (118565), Joao A. Fonseca (18408027), Eileen Wang (4471834), Camille Taillé (829699), Celeste M. Porsbjerg (9263975), Borja G. Cosio (3184737), Diahn-Warng Perng (Steve) (18408060), Alan Altraja (74156), Mark Hew (3203178), Tatsuya Nagano (636701), Guy G. Brusselle (7634108), Celine Bergeron (18407997), Désirée Larenas-Linnemann (12113454), David B. Price (3133764), David J. Jackson (4405432), Mona Al-Ahmad (12040516), Lakmini Bulathsinhala (3663172), Chau-Chyun Sheu (524362), Chin Kook Rhee (7492325), Kirsty Fletton (18408015), Enrico Heffler (6617369), Leif Bjermer (3291531), Bellanid Rodríguez-Cáceres (18408045), Stefania Nicola (6851225), Agnieszka Ławkiedraj (18408033), Neil Martin (73632), Luis Perez-De-Llano (18408042), John Busby (3509471), Mohsen Sadatsafavi (63962), John Abisheganaden (14581367), Nikolaos G. Papadopoulos (7677542), Tunn Ren Tay (3203172), Gregory P. Katsoulotos (18408003), Flavia Hoyte (18408030), Ming-Ju Tsai (770331), Michael E. Wechsler (7923218), Martina Zappa (18408051), Susanne Hansen (323324), Liam G. Heaney (7754321), Victoria Carter (232149), Jorge Máspero (18408057), Aaron Beastall (18408012), Peter G. Gibson (8250825), Wenjia Chen (844791), Li Ping Chung (18408021), Konstantinos Kostikas (361271), Charlotte Suppli Ulrik (7757765), Richard W. Costello (7934465), Riyad Al-Lehebi (18408006), Piotr Kuna (3549902), Arnaud Bourdin (376853), Takashi Iwanaga (2166256), Libardo Jiménez-Maldonado (18408069), Concetta Sirena (18408063), Paul E. Pfeffer (4984613), Bruce J. Kirenga (8823890), Pee Hwee Pang (7724246), Matthew J. Peters (8781407), Francesca Puggioni (6851219), Todor A. Popov (7583747), Pujan H. Patel (18408039), Luisa Ricciardi (12532573), Rohit Katial (12542123), Andriana I. Papaioannou (13531845), Diana Jimena Cano Rosales (18408018), Karin Dahl Assing (18408054), Florence Schleich (394436), Mariko Siyue Koh (9295747) +86 morecore +1 more sourceLysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez +3 morewiley +1 more sourceSmaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.Oleg Y. Dmitrievwiley +1 more source
