Results 241 to 250 of about 8,290,554 (306)

Biologic Therapy and Severe Asthma in Children

open access: yesBiomedicines, 2021
Severe asthma is a heterogeneous, complex and chronic disease widespread in the pediatric population. According to the recent findings about the different endotypes of asthma in children, each one characterized by specific intracellular molecular ...
Marina Attanasi   +2 more
exaly   +2 more sources

Gut microbiome profile in psoriatic patients treated and untreated with biologic therapy

Journal of Dermatology, 2021
There are increasing data about the role of the gut microbiome in various autoimmune diseases, including psoriasis, a chronic inflammatory and immune‐mediated disease. Current treatment strategies in psoriasis include immunomodulating biologic agents.
Laura Ottini   +2 more
exaly   +2 more sources

Does biologic therapy impact the development of PsA among patients with psoriasis?

Annals of the Rheumatic Diseases, 2021
Objective To examine the association of biologic therapy use for psoriasis with incident psoriatic arthritis (PsA) diagnosis. Methods A retrospective cohort study was conducted in the OptumInsights Electronic Health Record Database between 2006 and 2017 ...
Elana A. Meer   +13 more
semanticscholar   +1 more source

Coronary artery plaque characteristics and treatment with biologic therapy in severe psoriasis: results from a prospective observational study

open access: yesCardiovascular Research, 2019
AIMS The use of biologic therapy has increased over the past decade well beyond primary autoimmune diseases. Indeed, a recent trial using an anti-IL-1beta antibody reduced second myocardial infarction (MI) in those who have had MI. Psoriasis is a chronic
Jonathan Chung   +2 more
exaly   +2 more sources

Benefits of biologic therapy administered for asthma on co‐existent chronic rhinosinusitis: A real‐world study

International Forum of Allergy and Rhinology, 2021
Asthma and some chronic rhinosinusitis (CRS) subtypes are mediated by similar pathophysiologic mechanisms. The purpose of this study was to evaluate the effects of biologic therapy for asthma on co‐existent CRS in the “real‐world” setting.
S. Bajpai   +5 more
semanticscholar   +1 more source

Dual biologic therapy with Vedolizumab and Ustekinumab for refractory Crohn's disease in children.

European Journal of Gastroenterology and Hepathology, 2021
There is a paucity of treatment options for patients who have failed multiple biologics. A drawback of biologic therapies is their selectivity in targeting a single pathway.
Gadi Howard   +3 more
semanticscholar   +1 more source

Biologic Therapy

Clinics in Plastic Surgery, 2000
Biologic therapy has evolved as a fourth treatment option for patients with melanoma and other malignancies. Interrelated advances in molecular diagnostics and gene therapy techniques will further accelerate therapeutic advances in this new arena. A variety of biologic therapeutic options available to the patient with high risk melanoma are reviewed.
H, Edington, S, Agarwala, J M, Kirkwood
openaire   +2 more sources

Biological therapies for psoriasis

Expert Opinion on Biological Therapy, 2013
Biological therapies have revolutionized moderate-to-severe psoriasis treatment. Increased understanding of disease pathogenesis has yielded multiple therapeutic targets involving the IL-23/Th17 pathway, while current therapies continue to be monitored for long-term efficacy and safety.This review details current understanding of psoriasis ...
Bobbak, Mansouri   +2 more
openaire   +2 more sources

Economics of biological therapies

BMJ, 2009
Demand for biological drugs is putting pressure on health budgets.
Christopher J, Kelly, Fraz A, Mir
openaire   +2 more sources

Biologic therapies for asthma

Current Opinion in Pulmonary Medicine, 2010
The use of immunomodulators in asthma has been well established with omalizumab. Evidence is accumulating for other biologic agents. The following article presents an overview of current biologic therapies employed and under investigation in the treatment of asthma.Anti-immunoglobulin E and anti-interleukin-5 are best supported by current evidence ...
David, Gruenberg, William, Busse
openaire   +2 more sources

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