Results 61 to 70 of about 39,932 (328)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Clinical considerations in restorative dentistry - A narrative review

Journal of International Clinical Dental Research Organization, 2015
The relationship between periodontal health and the restoration of teeth is intimate and inseparable. Human teeth are designed in such a way that the individual tooth contributes significantly to their own support as well as collectively the teeth in the
Ashwini Tumkur Shivakumar, Sowmya Halasabalu Kalgeri, Sangeeta Dhir   +2 more
doaj   +1 more source

Time-gated transillumination and reflection by biological tissues and tissuelike phantoms: simulation versus experiment [PDF]

, 1997
A numerical method is presented to solve exactly the time-dependent diffusion equation that describes light transport in turbid media. The simulation takes into account spatial variations of the scattering and absorption factors of the medium and the ...
Alfano, Alper, Benaron, Boas, Boas, Chance, Contini, De Raedt, den Outer, Fishkin, H. De Raedt, Hebden, K. Michielsen, Kienle, Marchesini, Mitic, N. Garcı́a, O’Leary, O’Leary, Schmitt, Suzuki, Tromberg, Watson, Yodh   +23 more
core   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Unanswered questions on the use of biologics in pediatric asthma

World Allergy Organization Journal, 2023
The emergence of biologic therapies for the management of asthma has been a revolutionary change in our capacity to manage this disease.Since the launch of omalizumab, several other biologics have been marketed or are close to being marketed, suggesting ...
Antonio Nieto, MD, PhD, Zeinab A. El-Sayed, MD, PhD, René Maximiliano Gómez, PhD, Elham Hossny, MD, PhD, Wang Jiu-Yao, MD, DPhil, Ömer Kalayci, MD, Mário Morais-Almeida, Wanda Phipatanakul, MD, Paulo Marcio Pitrez, MD, César Fireth Pozo Beltrán, MD, Paraskevi Xepapadaki, MD, Nikolaos G. Papadopoulos, MD, PhD   +11 more
doaj   +1 more source

Volume Analysis of the Proximal Tibial Metaphysis [PDF]

, 2007
Purpose The Vitrea 2 imaging software (Vital Images Inc, Minnetonka, MN) was used for the volume analysis of the proximal tibial metaphysis. Materials and Methods Eighteen computed tomography scans of the proximal tibia were processed through the ...
Almeida, Luis Eduardo, Olsson, Alexis B., Wang, Kingsley   +2 more
core   +1 more source

A review on the prevention of inflammatory periimplant diseases [PDF]

, 2019
Background: An impressive number of dental implants are inserted worldwide. Evolution in dental implants and simplification of surgical techniques allowed a significant increase in the number of dentists involved in implant surgery.
Di Nardo, D., Passariello, C., Polimeni, A., Testarelli, L.   +3 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Autogenous tooth fragment reattachment: A multidisciplinary management for complicated crown-root fracture with biologic width violation

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2014
Fractures of multiple permanent anterior teeth can be a traumatic experience for children, with functional, esthetic and psychological aspects. The treatment of complicated crown-root fractures (CRFs) is more challenging when the biologic width is ...
Vinaya Kumar Kulkarni, Chitra P Bhusari, Divya S Sharma, Prashant Bhusari, Arpana V Bansal, Jeevanand Deshmukh   +5 more
doaj   +1 more source

One year in review: ultrasound in arthritis [PDF]

, 2016
Musculoskeletal ultrasound (MSUS) has become a relevant part of rheumatology practice and research because it substantially allows us to optimize management of rheumatic and musculoskeletal diseases. This non-invasive imaging modality is a valuable point-
IAGNOCCO, Annamaria, Naredo, Esperanza
core