Results 181 to 190 of about 4,765,787 (310)

Thorough Characterization of Two Sessein Derivatives with Potential Biological Activity. [PDF]

Molecules
Gómez-Rivera A, Barredo-Hernández CO, Santos-Vázquez S, Lobato-García CE, Gallegos-García AJ, López-Rodríguez R, Alvarez L, Pérez-García MD, González-Cortazar M, Torres-López JL, Medrano-Sánchez EJ.   +10 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Effects of Salinization, Oil Contamination, and Heavy Metals on Soil Biological Activity and Phytoremediants. [PDF]

Toxics
Rafikova G, Mukhamatdyarova S, Kuzina E, Kulbaeva L, Iskuzhina M, Korshunova T.   +5 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Substituent Effects Control the Biological Activity of Mn(II) Imidazo[1,2-a]pyridine Complexes. [PDF]

Molecules
Rydz M, Mazur T, Świtlicka A, Komarnicka UK, Wojtala D, Lesiów MK, Kyzioł A, Kędzierski P, Bieńko DC.   +8 more
europepmc   +1 more source

Biological activition of hydrogen [PDF]

Nature, 1997
Happe, R.P., Roseboom, W., Pierik, A.J., Albracht, S.P.J., Bagley, K.A.   +4 more
openaire   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Phytochemical Profile of <i>Convolvulus cantabrica</i> Extracts and Their Biological Activity. [PDF]

Molecules
Mahdadi KBE, Allaoua Z, Bensaad MS, Belahssini F, Bensouici C, Pinto DCGA, Cakmak YS, Haba H, Mossialos D, Stagos D, Akkal S.   +10 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Biological Activity and Structural Biology of Current KAT6A Inhibitor Chemotypes. [PDF]

J Med Chem
Suwandi A, Jin J, Zhao Y, Mudududdla R, Gee YS, Deora GS, Sun Y, Wei H, Huang F, He JS, George AJ, Hermans SJ, Leaver DJ, Parker MW, Baell JB.   +14 more
europepmc   +1 more source