Results 201 to 210 of about 2,148,890 (355)

Synthesis and biological characterization of a 17β hydroxysteroid dehydrogenase type 10 (17β-HSD10) inhibitor. [PDF]

RSC Med Chem
Dow LF, Pathirage R, Erickson HE, Amani E, Ronning DR, Trippier PC.   +5 more
europepmc   +1 more source

Bioactive ruthenium complexes: synthesis, characterization and biological assays

, 2014
Carolina R. Cardoso
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Implications for the assay and biological properties of interleukin-3 Results of a WHO international collaborative study

, 1996
Anthony R. Mire‐Sluis, Rose Gaines Das, Robin Thorpe   +2 more
openalex   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

CDK2 inhibitors: rationally directed discovery of a novel potent lead derived from cyclohepta[<i>e</i>]thieno[2,3-<i>b</i>]pyridine. [PDF]

RSC Med Chem
Ibrahim OF, Maklad RM, Abdu-Allah HHM, Syam YM, Bakhite EA.   +4 more
europepmc   +1 more source

Nanostructured lipid carriers as a potential strategy for incorporation of octyl methoxycinnamate: development, physicochemical characterization and in vitro biological assays

, 2016
Alice Haddad do [UNESP] Prado
openalex   +1 more source

P2‐046: The biological significance of a 96 gene expression assay developed to aid the diagnosis of Alzheimer's disease [PDF]

, 2011
Anders Lönneborg, Birgitte Booij, Philip D. Rye, Gisle Grave, Hilde‐Marie Andersen, Lena Kristiansen, Torbj⊘rn Lindahl, Line Røed, Praveen Sharma   +8 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

A NEW METHOD FOR THE BIOLOGICAL ASSAY OF CARDIOTONIC STEROIDS BASED ON THE POTENTIATION OF POTASSIUM-CONTRACTURE OF THE FROG VENTRICULAR MUSCLE

, 1971
Keisuke TAKEDA, Akira SAKUMA, Tatsuro Shigei   +2 more
openalex   +1 more source