Astrocyte heterogeneity in brain metastases
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
Differential associations between early life adversity subtypes and adolescent stress reactivity across neuroendocrine, autonomic, immune, and metabolic systems. [PDF]
Kuhlman KR, Pugh AJ, Rodgers EL.
europepmc +1 more source
Quantitative dissection of radioresistance in cancer cells: Oxygen depletion-induced biological versus chemical mechanisms and baseline mechanisms governed by HIF-1β-NRF2/TXNRD1. [PDF]
Takeuchi S +5 more
europepmc +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
CRISPR/Cas9-mediated miR-21 editing in high-grade urothelial carcinoma cells and its biological effects. [PDF]
Yi Lin Lee MC +10 more
europepmc +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
A context-aware interpretive framework for lymphocyte immunophenotyping by flow cytometry. [PDF]
Villegas-Valverde CA +1 more
europepmc +1 more source
Interaction of NDRG1 and TGM2 Modulates DNA Replication and Repair. [PDF]
Doh HM, Kozlova N, Cruz KA, Muranen T.
europepmc +1 more source
Ion-coupled transfersome complexes for enhanced transdermal NAD<sup>+</sup> repletion and mitigation of cellular senescence signatures. [PDF]
Kang S +14 more
europepmc +1 more source
Early Osteogenic and Stromal Marker Responses of Osteoblast-like and Bone-Marrow Stromal Cell Lines to a Hyaluronic Acid-Coated Xenogeneic Bone Graft: An Exploratory In Vitro Analysis. [PDF]
Mayer Y +5 more
europepmc +1 more source

