Hyperpolarized NMR Probes for Biological Assays [PDF]
Sensors, 2014 During the last decade, the development of nuclear spin polarization enhanced (hyperpolarized) molecular probes has opened up new opportunities for studying the inner workings of living cells in real time.
Sebastian Meier +3 more
doaj +10 more sources
Machine Learning Strategies When Transitioning between Biological Assays [PDF]
Journal of Chemical Information and Modeling, 2021 Machine learning is widely used in drug development to predict activity in biological assays based on chemical structure. However, the process of transitioning from one experimental setup to another for the same biological endpoint has not been ...
Staffan Arvidsson Mcshane +2 more
exaly +5 more sources
AutoPlate: Rapid Dose-Response Curve Analysis for Biological Assays [PDF]
Frontiers in Immunology, 2022 The emergence of COVID-19 has emphasised that biological assay data must be analysed quickly to develop safe, effective and timely vaccines/therapeutics.
Phil Palmer +9 more
doaj +5 more sources
Accurate Prediction of Biological Assays with High-Throughput Microscopy Images and Convolutional Networks [PDF]
Journal of Chemical Information and Modeling, 2019 Predicting the outcome of biological assays based on high-throughput imaging data is a highly promising task in drug discovery since it can tremendously increase hit rates and suggest novel chemical scaffolds.
Sepp Hochreiter +2 more
exaly +5 more sources
Methods of Inactivation of SARS-CoV-2 for Downstream Biological Assays. [PDF]
J Infect Dis, 2020 The scientific community has responded to the coronavirus disease 2019 (COVID-19) pandemic by rapidly undertaking research to find effective strategies to reduce the burden of this disease.
Patterson EI +10 more
europepmc +3 more sources
Comparison between In Vitro Chemical and Ex Vivo Biological Assays to Evaluate Antioxidant Capacity of Botanical Extracts. [PDF]
Antioxidants (Basel), 2021 The anti-oxidative activity of plant-derived extracts is well-known and confers health-promoting effects on functional foods and food supplements. Aim of this work is to evaluate the capability of two different assays to predict the real biological ...
Pasqualetti V +7 more
europepmc +2 more sources
Dimensional distribution control of elongate mineral particles for their use in biological assays. [PDF]
MethodsX, 2020 The aim of the present method is to reduce the dimensional variability of asbestos, elongate mineral particles, and other asbestiform minerals for use in biological assays.
Vigliaturo R +3 more
europepmc +2 more sources
TrAC - Trends in Analytical Chemistry, 2021 The quality analysis of water, pharmaceutical and environmental compounds is a basic subject for human health. The presence of low-quality drugs, biological toxins and chemical compounds in water or forbidden additives in the nourishments lead to ...
Ali Jahanban-Esfahlan +2 more
exaly +2 more sources
Laser Inscription of Microfluidic Devices for Biological Assays
ACS Applied Materials & Interfaces, 2019 A rapid and direct CO2 laser ablation method was developed to create superhydrophilic surfaces and arrays of hydrophobic-superhydrophilic patterns for application in bioassays.
Muhammad Umair Hassan +2 more
exaly +2 more sources
Structured data sets of compounds with multi-target and corresponding single-target activity from biological assays [PDF]
Future Science OA, 2021 Aim: Providing compound data sets for promiscuity analysis with single-target (ST) and multi-target (MT) activity, taking confirmed inactivity against targets into account. Methodology: Compounds and target annotations are extracted from screening assays.
Christian Feldmann +2 more
doaj +2 more sources