Results 11 to 20 of about 168 (163)

Hyperpolarized NMR Probes for Biological Assays [PDF]

Sensors, 2014
During the last decade, the development of nuclear spin polarization enhanced (hyperpolarized) molecular probes has opened up new opportunities for studying the inner workings of living cells in real time. The hyperpolarized probes are produced ex situ, introduced into biological systems and detected with high sensitivity and contrast against ...
Sebastian Meier, Pernille Rose Jensen, Magnus Karlsson   +2 more
exaly   +4 more sources

Computation of Biological Assays [PDF]

Nature, 1946
IN microbiological assays of essential amino-acids, and of members of the vitamin B2 complex other than riboflavin and nicotinic acid, it is usually found that when the mean responses are plotted against either the dose or the logarithm of the dose, a non linear relationship is obtained.
openaire   +2 more sources

A Biological Assay of Tuberculins [PDF]

Biometrics, 1949
A FEW YEARS AGO it was decided to carry out under the authority ^ of the Agricultural Research Council a specific test, using bovine subjects, of the relative potency of two tuberculin preparations, which may be designated as Standard and Weybridge respectively.
openaire   +2 more sources

Sequential Sampling in Biological Assay [PDF]

Nature, 1953
IN an investigation relating to the isolation and purification of chorionic gonadotrophin from pregnancy urine, the following problem has arisen : “Does fraction A contain at least the amount X of chorionic gonadotrophin?” It was necessary to answer this question in the shortest possible time and to use as little material of A as possible.
E, BUKOVICS, F X, WOHLZOGEN
openaire   +2 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Mathematics of Biological Assay

Nature, 1944
IF in a biological assay the mean responses, y11, y12, of two groups of n animals to doses of a standard preparation the logarithms of which are x11, x12, are compared with the mean responses, y21, y22 to doses of the preparation under test the logarithms of which are x21, x22, it is often possible to express the relationship between dosage and ...
openaire   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Biological Assay of Cephalosporin C [PDF]

Journal of General Microbiology, 1962
SUMMARY: A method of assaying the antibiotic cephalosporin C in low concentration in culture fluids by using a strain of Vibrio cholerae is described. The formation of spheroplasts of the test organism in subinhibitory concentrations of the antibiotic and chemically related compounds is discussed.
J M, BOND, R W, BRIMBLECOMBE, R C, CODNER   +2 more
openaire   +2 more sources

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source