Results 11 to 20 of about 9,490,238 (346)

Copolymer-Coated Gold Nanoparticles: Enhanced Stability and Customizable Functionalization for Biological Assays [PDF]

Biosensors
Gold nanoparticles (AuNPs) play a vital role in biotechnology, medicine, and diagnostics due to their unique optical properties. Their conjugation with antibodies, antigens, proteins, or nucleic acids enables precise targeting and enhances biosensing ...
Dario Brambilla, Federica Panico, Lorenzo Zarini, Alessandro Mussida, Anna M. Ferretti, Mete Aslan, M. Selim Ünlü, Marcella Chiari   +7 more
doaj   +2 more sources

Binding abilities of polyaminocyclodextrins: polarimetric investigations and biological assays [PDF]

Beilstein Journal of Organic Chemistry, 2017
Three polyaminocyclodextrin materials, obtained by direct reaction between heptakis(6-deoxy-6-iodo)-β-cyclodextrin and the proper linear polyamines, were investigated for their binding properties, in order to assess their potential applications in ...
Marco Russo, Daniele La Corte, Annalisa Pisciotta, Serena Riela, Rosa Alduina, Paolo Lo Meo   +5 more
doaj   +2 more sources

A performance evaluation of commercial fibrinogen reference preparations and assays for Clauss and PT-derived fibrinogen [PDF]

, 2002
The wide availability of fibrinogen estimations based on the prothrombin time (PT-Fg) has caused concern about the variability and clinical utility of fibrinogen assays.
Lowe, G.D.O., Lawrie, A.S., Howarth, D., Rumley, A., Mackie, I.J., Gaffney, P.J., Kitchen, S., Purdy, G., Rigsby, P., Martin, J.   +9 more
core   +5 more sources

Quality Management in Polish Biobanking Network—Current Status Before the Implementation of Unified and Harmonized Integrated Quality Management System

Frontiers in Medicine, 2022
In 2017, Polish Biobanking Network was established in Poland, within BBMRI.pl project titled “Organization of Polish Biobanking Network within the Biobanking and Biomolecular Resources Research Infrastructure BBMRI-ERIC” as a strategic scientific ...
Agnieszka Matera-Witkiewicz, Agnieszka Matera-Witkiewicz, Magdalena Krupińska, Magdalena Krupińska, Patrycja Sitek, Patrycja Sitek, Michał Laskowski, Michał Laskowski, Karolina Zagórska, Karolina Zagórska, Joanna Gleńska-Olender, Joanna Gleńska-Olender   +11 more
doaj   +1 more source

The Degradation Product of Ramipril Is Potentially Carcinogenic, Genotoxic and Mutagenic

Applied Sciences, 2023
(1) Background: The aim of this study was to identify the degradation product of ramipril (RAM) formed under dry air and to verify its potential modes of carcinogenicity. We intended to check whether its formation and presence in final dosage forms could
Katarzyna Regulska, Agnieszka Matera-Witkiewicz, Aleksandra Mikołajczyk, Beata J. Stanisz   +3 more
doaj   +1 more source

Single nucleus multi-omics regulatory landscape of the murine pituitary

Nature Communications, 2021
The pituitary gland plays important roles in the regulation of key physiological functions. Here the authors provide a multiomics atlas including transcriptome, chromatin accessibility, and methylation status of over 70,000 single nuclei (sn) from mouse ...
Frederique Ruf-Zamojski, Zidong Zhang, Michel Zamojski, Gregory R. Smith, Natalia Mendelev, Hanqing Liu, German Nudelman, Mika Moriwaki, Hanna Pincas, Rosa Gomez Castanon, Venugopalan D. Nair, Nitish Seenarine, Mary Anne S. Amper, Xiang Zhou, Luisina Ongaro, Chirine Toufaily, Gauthier Schang, Joseph R. Nery, Anna Bartlett, Andrew Aldridge, Nimisha Jain, Gwen V. Childs, Olga G. Troyanskaya, Joseph R. Ecker, Judith L. Turgeon, Corrine K. Welt, Daniel J. Bernard, Stuart C. Sealfon   +27 more
doaj   +1 more source

Compound dataset and custom code for deep generative multi-target compound design

Future Science OA, 2021
Aim: Generating a data and software infrastructure for evaluating multi-target compound (MT-CPD) design via deep generative modeling. Methodology: The REINVENT 2.0 approach for generative modeling was extended for MT-CPD design and a large benchmark data
Thomas Blaschke, Jürgen Bajorath
doaj   +1 more source

Zn(II) binding to pramlintide results in a structural kink, fibril formation and antifungal activity

Scientific Reports, 2022
The antimicrobial properties of amylin, a 37-amino acid peptide hormone, co-secreted with insulin from the pancreas, are far less known than its antidiabetic function.
Dorota Dudek, Emilia Dzień, Joanna Wątły, Agnieszka Matera-Witkiewicz, Aleksandra Mikołajczyk, Agata Hajda, Joanna Olesiak-Bańska, Magdalena Rowińska-Żyrek   +7 more
doaj   +1 more source

Freestanding hydrogel lumens for modeling blood vessels and vasodilation

SLAS Technology, 2022
Lumen structures exist throughout the human body, and the vessels of the circulatory system are essential for carrying nutrients and oxygen and regulating inflammation.
Ashley M. Dostie, Hannah G. Lea, Ulri N. Lee, Tammi L. van Neel, Erwin Berthier, Ashleigh B. Theberge   +5 more
doaj   +1 more source

Data transformation in biological assays

Pesquisa Florestal Brasileira, 2021
The analysis of variance is the statistical test most used for comparison of three or more means simultaneously. Its application requires, however, the compliance to some assumptions, with main emphasis on normality of the data and homoscedasticity of ...
Sylvio Péllico Netto, Alexandre Behling
doaj   +1 more source