Results 11 to 20 of about 3,956,990 (303)
Compound dataset and custom code for deep generative multi-target compound design
Future Science OA, 2021 Aim: Generating a data and software infrastructure for evaluating multi-target compound (MT-CPD) design via deep generative modeling. Methodology: The REINVENT 2.0 approach for generative modeling was extended for MT-CPD design and a large benchmark data
Thomas Blaschke, Jürgen Bajorath
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Freestanding hydrogel lumens for modeling blood vessels and vasodilation
SLAS Technology, 2022 Lumen structures exist throughout the human body, and the vessels of the circulatory system are essential for carrying nutrients and oxygen and regulating inflammation.
Ashley M. Dostie +5 more
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Data transformation in biological assays
Pesquisa Florestal Brasileira, 2021 The analysis of variance is the statistical test most used for comparison of three or more means simultaneously. Its application requires, however, the compliance to some assumptions, with main emphasis on normality of the data and homoscedasticity of ...
Sylvio Péllico Netto, Alexandre Behling
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Water Science and Technology, 2022 Cadmium sulphide (CdS) nanoparticles (NPs) were synthesized through hydrothermal route and characterized by UV-Vis spectroscopy, X-ray diffraction (XRD), Energy dispersive X-ray analysis, Scanning electron microscopy (SEM), Fourier transform infrared ...
Sundas Ali +5 more
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Biomolecules, 2020 Predicting compounds with single- and multi-target activity and exploring origins of compound specificity and promiscuity is of high interest for chemical biology and drug discovery. We present a large-scale analysis of compound promiscuity including two
Christian Feldmann +2 more
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Separations, 2022 The title ligand (L”x), methyl 2-((4-cyanophenyl)(hydroxy)methyl)acrylate was synthesized following the Morita-Baylis-Hillman reaction scheme. Spectroscopic techniques such as: UV- Visible, FT-IR, ESI-MS, and 1H NMR helped in characterization of the L”x.
Shazia Ishfaq +9 more
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Frontiers in Bioengineering and Biotechnology, 2022 Perinatal derivatives or PnDs refer to tissues, cells and secretomes from perinatal, or birth-associated tissues. In the past 2 decades PnDs have been highly investigated for their multimodal mechanisms of action that have been exploited in various ...
Antonietta R. Silini +17 more
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Computation of Biological Assays [PDF]
Nature, 1946 IN microbiological assays of essential amino-acids, and of members of the vitamin B2 complex other than riboflavin and nicotinic acid, it is usually found that when the mean responses are plotted against either the dose or the logarithm of the dose, a non linear relationship is obtained.
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A Biological Assay of Tuberculins [PDF]
Biometrics, 1949 A FEW YEARS AGO it was decided to carry out under the authority ^ of the Agricultural Research Council a specific test, using bovine subjects, of the relative potency of two tuberculin preparations, which may be designated as Standard and Weybridge respectively.
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Sensors, 2020 Graphene oxide (GO)/peptide complexes as a promising disease biomarker analysis platform have been used to detect proteolytic activity by observing the turn-on signal of the quenched fluorescence upon the release of peptide fragments.
Seongsoo Kim +6 more
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