Results 21 to 30 of about 6,386,574 (334)
Zn(II) binding to pramlintide results in a structural kink, fibril formation and antifungal activity
Scientific Reports, 2022 The antimicrobial properties of amylin, a 37-amino acid peptide hormone, co-secreted with insulin from the pancreas, are far less known than its antidiabetic function.
Dorota Dudek +7 more
doaj +1 more source
Compound dataset and custom code for deep generative multi-target compound design
Future Science OA, 2021 Aim: Generating a data and software infrastructure for evaluating multi-target compound (MT-CPD) design via deep generative modeling. Methodology: The REINVENT 2.0 approach for generative modeling was extended for MT-CPD design and a large benchmark data
Thomas Blaschke, Jürgen Bajorath
doaj +1 more source
Freestanding hydrogel lumens for modeling blood vessels and vasodilation
SLAS Technology, 2022 Lumen structures exist throughout the human body, and the vessels of the circulatory system are essential for carrying nutrients and oxygen and regulating inflammation.
Ashley M. Dostie +5 more
doaj +1 more source
Physicochemical properties, water solubility and pharmacokinetics predicted data for benzazepinones and paullones tested in biological assays. [PDF]
, 2023 Physicochemical properties, water solubility and pharmacokinetics predicted data for benzazepinones and paullones tested in biological assays.
Irina Ihnatenko (16415232) +9 more
core +1 more source
Data transformation in biological assays
Pesquisa Florestal Brasileira, 2021 The analysis of variance is the statistical test most used for comparison of three or more means simultaneously. Its application requires, however, the compliance to some assumptions, with main emphasis on normality of the data and homoscedasticity of ...
Sylvio Péllico Netto, Alexandre Behling
doaj +1 more source
Water Science and Technology, 2022 Cadmium sulphide (CdS) nanoparticles (NPs) were synthesized through hydrothermal route and characterized by UV-Vis spectroscopy, X-ray diffraction (XRD), Energy dispersive X-ray analysis, Scanning electron microscopy (SEM), Fourier transform infrared ...
Sundas Ali +5 more
doaj +1 more source
Biomolecules, 2020 Predicting compounds with single- and multi-target activity and exploring origins of compound specificity and promiscuity is of high interest for chemical biology and drug discovery. We present a large-scale analysis of compound promiscuity including two
Christian Feldmann +2 more
doaj +1 more source
Cytogenetic biological dosimetry assays: recent developments and updates
Radiation Oncology Journal, 2021 Biological dosimetry is the measurement of radiation-induced changes in the human to measure short and long-term health risks. Biodosimetry offers an independent means of obtaining dose information and also provides diagnostic information on the ...
T. Gnanasekaran
semanticscholar +1 more source
Separations, 2022 The title ligand (L”x), methyl 2-((4-cyanophenyl)(hydroxy)methyl)acrylate was synthesized following the Morita-Baylis-Hillman reaction scheme. Spectroscopic techniques such as: UV- Visible, FT-IR, ESI-MS, and 1H NMR helped in characterization of the L”x.
Shazia Ishfaq +9 more
doaj +1 more source
A performance evaluation of commercial fibrinogen reference preparations and assays for Clauss and PT-derived fibrinogen [PDF]
, 2002 The wide availability of fibrinogen estimations based on the prothrombin time (PT-Fg) has caused concern about the variability and clinical utility of fibrinogen assays.
Lowe, G.D.O. +19 more
core +1 more source