Results 81 to 90 of about 6,386,574 (334)

Chrysin-Loaded Microemulsion: Formulation Design, Evaluation and Antihyperalgesic Activity in Mice

Applied Sciences, 2022
Chrysin is a bioactive flavonoid found in pollens, passion flowers, honey, royal jelly, and propolis, which is commonly used as an ingredient in natural food supplements and is primarily responsible for their pharmacological properties.
Ízola Morais de Medeiros Ramalho, Gabriela Suassuna Bezerra, Elissa Arantes Ostrosky, Márcio Ferrari, Verônica da Silva Oliveira, Alcides de Oliveira Wanderley Neto, Jullyana de Souza Siqueira Quintans, Fabiolla Rocha Santos Passos, Luana Heimfarth, Lucindo José Quintans-Júnior, Bolívar Ponciano Goulart de Lima Damasceno, Attilio Converti, Ádley Antonini Neves de Lima   +12 more
doaj   +1 more source

Biological assays with special reference to biological standards [PDF]

Journal of Hygiene, 1950
A paper on biological assays and biological standards might be expected to start with a definition. What is a biological assay and what is a biological standard? However, I shall for the moment make the somewhat doubtful assumption that we all know the answer to those questions but shall return to them later, making a start meanwhile by discussing some
openaire   +2 more sources

Biomolecular simulations: From dynamics and mechanisms to computational assays of biological activity

WIREs Computational Molecular Science, 2018
Biomolecular simulation is increasingly central to understanding and designing biological molecules and their interactions. Detailed, physics‐based simulation methods are demonstrating rapidly growing impact in areas as diverse as biocatalysis, drug ...
D. Huggins, P. Biggin, M. A. Dämgen, J. Essex, Sarah A. Harris, Richard H. Henchman, S. Khalid, Antonija Kuzmanic, C. Laughton, J. Michel, A. Mulholland, E. Rosta, M. Sansom, Marc W. van der Kamp   +13 more
semanticscholar   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

Discovery and validation of SIRT2 inhibitors based on tenovin-6 : use of a 1H-NMR method to assess deacetylase activity [PDF]

, 2012
The search for potent and selective sirtuin inhibitors continues as chemical tools of this type are of use in helping to assign the function of this interesting class of deacetylases.
Pirrie, L, Sonia Lain, Major, LL, Zubriene, Asta, Lebl, T, Matulis, Daumantas, Lisa Pirrie, Morkunaite, Vaida, Tomas Lebl, McCarthy, Anna R., Asta Zubrienė, Louise L. Major, Matulis, D, Lain, Sonia, Daumantas Matulis, Morkunaite, V, Nicholas J. Westwood, Vaida Morkūnaitė, Major, Louise L., Westwood, NJ, Anna R. McCarthy, McCarthy, AR, Zubriene, A, Lebl, Tomas, Lain, S, Westwood, Nicholas J., Pirrie, Lisa   +26 more
core   +1 more source

A COMPARATIVE BIOLOGICAL STUDY, RELATED TO THE THERAPEUTICALLY EFFECTS OF PAN BREAD PROVIDED WITH SOME NATURAL FOODSTUFFS UTILIZED, ON THE EXPERIMENTAL RATS [PDF]

Journal of Food and Dairy Sciences, 2008
To understand the link between some nutritional diseases and different natural sources of carbohydrates, formulated pan bread (control) was prepared and investigated in a comparative study with other formulae in which an acceptable amount of foodstuffs ...
Mona Doeidar, Ebtesam Mohamed, M. Saleh
doaj   +1 more source

Enzymatic Synthesis and Antimicrobial Activity of Oligomer Analogues of Medicinal Biopolymers from Comfrey and Other Species of the Boraginaceae Family

Pharmaceutics, 2022
This study reports the first enzymatic synthesis leading to several oligomer analogues of poly[3-(3,4-dihydroxyphenyl)glyceric acid]. This biopolymer, extracted from plants of the Boraginaceae family has shown a wide spectrum of pharmacological ...
Maia Merlani, Dieter M. Scheibel, Vakhtang Barbakadze, Lali Gogilashvili, Lela Amiranashvili, Athina Geronikaki, Valentina Catania, Domenico Schillaci, Giuseppe Gallo, Ivan Gitsov   +9 more
doaj   +1 more source

Long‐Term Outcomes of Patients With Relapsed/Refractory Neuroblastoma Treated on ANBL1221: A Report From the Children's Oncology Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Results of COG ANBL1221 changed treatment paradigms for patients with relapsed/refractory neuroblastoma. Chemoimmunotherapy with irinotecan/temozolomide/dinutuximab is now used as both bridge therapy following suboptimal response to induction and as treatment in first relapse.
Elizabeth Sokol, Arlene Naranjo, Lulu Chen, Rajen Mody, Steven G. DuBois, Rochelle Bagatell, Navin Pinto   +6 more
wiley   +1 more source

Mutational tuning of galectin-3 specificity and biological function. [PDF]

, 2010
Galectins are defined by a conserved beta-galactoside binding site, which has been linked to many of their important functions in e.g. cell adhesion, signaling and intracellular trafficking.
Emma Salomonsson, James M. Rini, Öberg, Christopher,, Ruth Hendus-Altenburger, Kahl Knutson, Barbro,, Eva Nordberg-Karlsson, Carlsson, Michael C, Nilsson, Rickard, Barbro Kahl-Knutson, Michael C. Carlsson, Veronica Osla, Karlsson, Anna,, Ulf J. Nilsson, Anders Sundin, Karlsson, Anna, Salomonsson, Emma,, Nordberg-Karlsson, Eva, Sundin, Anders,, Salomonsson, Emma, Carlsson, Michael, Rickard Nilsson, Nordberg Karlsson, Eva,, Anna Karlsson, Nordberg Karlsson, Eva, Nilsson, Ulf J, Christopher T. Öberg, Rini, James M, Kahl Knutson, Barbro, Nilsson, Ulf,, Öberg, Christopher, Osla, Veronica, Hendus-Altenburger, Ruth, Hakon Leffler, Osla, Veronica,, Carlsson, Michael,, Nilsson, Ulf, Oberg, Christopher T, Lund University., Leffler, Hakon, Sundin, Anders, Leffler, Hakon,   +40 more
core   +1 more source

Biological assay of glucagon in rabbits [PDF]

Diabetologia, 1969
Bioassay of glucagon based on the hyper-glycaemic activity was investigated in normal rabbits. — It was shown that the index of precision (λ) derived from the dose response curve is about 1.2, which means that several hundred animals are required per assay in order to obtain a reasonably narrow confidence interval. Triple cross-over design improved the
F, Tarding, P, Nielsen, B, Keiser-Nielsen, A V, Nielsen   +3 more
openaire   +2 more sources