Fetal bovine serum contains biologically available ATP [PDF]
Purinergic Signalling, 2023 AbstractATP is a ubiquitous extracellular messenger released in a wide number of pathophysiological conditions. ATP is known to be present in minute amounts in the extracellular space in healthy tissues and in the blood, and to modulate a multiplicity of cell responses. Cell culture systems are widely used to explore purinergic signaling.
Valentina Vultaggio-Poma +7 more
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Viral Lysis Alters the Optical Properties and Biological Availability of Dissolved Organic Matter Derived from Prochlorococcus Picocyanobacteria. [PDF]
Appl Environ Microbiol, 2021 Xiao X +9 more
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Biological availability of mineral elements
Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Гжицького. Серія: Сільськогосподарські наукиThe animal husbandry industry is the leading branch of our country’s agro-industrial complex, on the one hand, its development determines the level of public consumption of valuable food products, and on the other hand, the economic well-being of the ...
I. I. Khabinets, N. V. Novhorodska
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Co-administration of herbal inhibitors of P-glycoprotein with renal drugs enhance their bioavailability– In silico approach [PDF]
Journal of HerbMed Pharmacology, 2023 Introduction: Multidrug resistance (MDR) is primarily associated with reduced intracellular drug accumulation owing to overexpression of p-glycoprotein, an active efflux transporter.
Chandana Roy, Pratiti Ghosh
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Permeation enhancement effects of leaf materials from different aloe species on in vitro and ex vivo nasal epithelial models [PDF]
Journal of HerbMed Pharmacology, 2020 Introduction: The nasal route of drug administration offers an alternative way for oral drug delivery and has the benefit of avoiding first-pass metabolism through drug delivery directly into the systemic circulation.
Werner Gerber +5 more
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Relative Bioavailability of Trace Minerals in Production Animal Nutrition: A Review
Animals, 2022 The importance of dietary supplementation of animal feeds with trace minerals is irrefutable, with various forms of both organic and inorganic products commercially available. With advances in research techniques, and data obtained from both in-vitro and
Laurann Byrne, Richard A. Murphy
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Antibiotics, 2021 Background: Tuberculosis (TB) patients admitted to intensive care units (ICU) have high mortality rates. It is uncertain whether the pharmacokinetics of first-line TB drugs in ICU patients are different from outpatients.
Francisco Beraldi-Magalhaes +10 more
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Bioequivalence assessment of the two brands of glimepiride tablets [PDF]
Vojnosanitetski Pregled, 2006 Background/Aim. Glimepiride, as an antidiabetic from the group of sulfonylurea, is administered perorally in the treatment of diabetes mellitus. The aim of this study was to compare pharmacokinetic profiles and relative bioavailabilities of the two oral ...
Jovanović Dušan +4 more
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A pharmacokinetic comparison of three pharmaceutical formulations of nimesulide in healthy volunteers [PDF]
Vojnosanitetski Pregled, 2005 Background/Aim. Switching the patient from one pharmaceutical formulation of the same drug to another, may lead to therapeutic inadequancy in some cases. To minimize the risk, careful pharmacokinetic studies are desired in the pre-registration period and
Jovanović Dušan +3 more
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Preparation and characterization of morphine gelatine microspheres
Designed Monomers and Polymers, 2023 Morphine is a widely used opioid analgesic. However, standard morphine dosages and administration methods exhibit a short half-life and pose a risk of respiratory depression.
Xin Jin, Jun Ji, Yonghai Sun
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