Results 101 to 110 of about 2,832,681 (326)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Biological Soil Crusts of Arctic Svalbard—Water Availability as Potential Controlling Factor for Microalgal Biodiversity

open access: yesFrontiers in Microbiology, 2017
In the present study the biodiversity of biological soil crusts (BSCs) formed by phototrophic organisms were investigated on Arctic Svalbard (Norway).
Nadine Borchhardt   +4 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Evaluation of the chemical composition, protein quality and digestibility of lupin (Lupinus albus and Lupinus angustifolius)

open access: yesO Mundo da Saúde, 2014
The purpose of this study was to determine the protein quality of lupin (Lupinus albus and Lupinus angustifolius) and to determine their chemical composition, including dietary fiber.
Márcia Regina Pereira Monteiro   +6 more
doaj  

The Nutrient Response Transcriptional Regulome of Arabidopsis

open access: yesiScience, 2019
Summary: Plants respond actively to changes in their environment. Variations in nutrient availability elicit substantial transcriptional reprogramming, and we aimed to systematically describe these adjustments and identify the regulators responsible ...
Tzvetina Brumbarova, Rumen Ivanov
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Bioavailability comparison study of two benzathine benzylpenicillin 1,200,000 IU intramuscular formulations in healthy male participants under fast state

open access: yesDST
Introduction: Benzathine benzylpenicillin G is a drug present in the list of essential medicines of the World Health Organization and largely used in Brazil, where this antibiotic is used for treating pneumonias, pharyngitis, syphilis, and other ...
Vinicius Marcondes Rezende   +7 more
doaj   +1 more source

Assemblage of a semi-arid annual plant community: abiotic and biotic filters act hierarchically.

open access: yesPLoS ONE, 2012
The study of species coexistence and community assembly has been a hot topic in ecology for decades. Disentangling the hierarchical role of abiotic and biotic filters is crucial to understand community assembly processes.
Arantzazu L Luzuriaga   +3 more
doaj   +1 more source

Prevention, Eradication, and Containment of Invasive Species: Illustrations from Hawaii [PDF]

open access: yes
Invasive species change ecosystems and the economic services such ecosystems provide. Optimal policy will minimize the expected damages and costs of prevention and control.
Burnett, Kimberly M.   +3 more
core   +1 more source

Sun exposure drives Antarctic cryptoendolithic community structure and composition [PDF]

open access: yes, 2019
The harsh environmental conditions of the ice-free regions of Continental Antarctica are considered one of the closest Martian analogues on Earth. There, rocks play a pivotal role as substratum for life and endolithism represents a primary habitat for ...
Coleine, Claudia   +4 more
core  

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