Results 121 to 130 of about 1,755,454 (302)

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Biological availability of digoxin. [PDF]

British heart journal, 1973
J, Hamer, D, Chamberlain
openaire   +4 more sources

Timing of rainfall influences juvenile and yearling mass of a long-lived herbivore in a semiarid environment

Scientific Reports
Resource availability is a primary factor predicting population performance. Synchrony between resource availability and consumer requirements plays a critical role in reproduction, and mismatches in the timing of resource availability and consumer ...
Miranda L. Hopper, Bryan D. Spencer, Randy W. DeYoung, Aaron M. Foley, J. Alfonso Ortega-Santos, Timothy E. Fulbright, David G. Hewitt, Landon R. Schofield, Tyler A. Campbell, Michael J. Cherry   +9 more
doaj   +1 more source

Nutrient enrichment, propagule pressure, and herbivory interactively influence the competitive ability of an invasive alien macrophyte Myriophyllum aquaticum

Frontiers in Plant Science
IntroductionFreshwater ecosystems are susceptible to invasion by alien macrophytes due to their connectivity and various plant dispersal vectors. These ecosystems often experience anthropogenic nutrient enrichment, favouring invasive species that ...
Ru Huang, Ru Huang, Ru Huang, Ru Huang, Ayub M. O. Oduor, Yimin Yan, Yimin Yan, Yimin Yan, Weicheng Yu, Weicheng Yu, Weicheng Yu, Chuanxin Chao, Chuanxin Chao, Chuanxin Chao, Lei Dong, Lei Dong, Lei Dong, Shaofei Jin, Shaofei Jin, Shaofei Jin, Shaofei Jin, Feng Li, Feng Li, Feng Li, Feng Li   +24 more
doaj   +1 more source

Assessing risks and benefits of floral supplements in conservation biological control

, 2010
The use of flowering field margins is often proposed as a method to support biological control in agro-ecosystems. In addition to beneficial insects, many herbivores depend on floral food as well.
Termorshuizen, A.J., Winkler, K., Aad J. Termorshuizen, van Lenteren, J.C., Felix L. Wäckers, Wackers, F.L., Joop C. van Lenteren, Karin Winkler, Lenteren, J.C., van   +8 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

In Vitro Evaluation of the Biological Availability of Hyaluronic Acid Polyethylene Glycols-Cross-Linked Hydrogels to Bovine Testes Hyaluronidase. [PDF]

Biomed Res Int, 2019
Zerbinati N, Mocchi R, Galadari H, Maccario C, Maggi M, Rauso R, Passi A, Esposito C, Sommatis S.   +8 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source