Results 121 to 130 of about 5,256,148 (309)

Biological availability of digoxin. [PDF]

British heart journal, 1973
J, Hamer, D, Chamberlain
openaire   +4 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1888

, 1889
Annual report of the Marine Biological Laboratory in Woods Hole. 1888.
Marine Biological Laboratory (Woods Hole MA)
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1892

, 1892
Annual report of the Marine Biological Laboratory in Woods Hole. 1892.
Marine Biological Laboratory (Woods Hole MA)
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1983

, 1983
Annual report of the Marine Biological Laboratory in Woods Hole. 1983.
Marine Biological Laboratory (Woods Hole MA)
core  

Timing of rainfall influences juvenile and yearling mass of a long-lived herbivore in a semiarid environment

Scientific Reports
Resource availability is a primary factor predicting population performance. Synchrony between resource availability and consumer requirements plays a critical role in reproduction, and mismatches in the timing of resource availability and consumer ...
Miranda L. Hopper, Bryan D. Spencer, Randy W. DeYoung, Aaron M. Foley, J. Alfonso Ortega-Santos, Timothy E. Fulbright, David G. Hewitt, Landon R. Schofield, Tyler A. Campbell, Michael J. Cherry   +9 more
doaj   +1 more source

Nutrient enrichment, propagule pressure, and herbivory interactively influence the competitive ability of an invasive alien macrophyte Myriophyllum aquaticum

Frontiers in Plant Science
IntroductionFreshwater ecosystems are susceptible to invasion by alien macrophytes due to their connectivity and various plant dispersal vectors. These ecosystems often experience anthropogenic nutrient enrichment, favouring invasive species that ...
Ru Huang, Ru Huang, Ru Huang, Ru Huang, Ayub M. O. Oduor, Yimin Yan, Yimin Yan, Yimin Yan, Weicheng Yu, Weicheng Yu, Weicheng Yu, Chuanxin Chao, Chuanxin Chao, Chuanxin Chao, Lei Dong, Lei Dong, Lei Dong, Shaofei Jin, Shaofei Jin, Shaofei Jin, Shaofei Jin, Feng Li, Feng Li, Feng Li, Feng Li   +24 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source