Results 101 to 110 of about 2,906,575 (298)

The Nutrient Response Transcriptional Regulome of Arabidopsis

iScience, 2019
Summary: Plants respond actively to changes in their environment. Variations in nutrient availability elicit substantial transcriptional reprogramming, and we aimed to systematically describe these adjustments and identify the regulators responsible ...
Tzvetina Brumbarova, Rumen Ivanov
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Evaluation of the chemical composition, protein quality and digestibility of lupin (Lupinus albus and Lupinus angustifolius)

O Mundo da Saúde, 2014
The purpose of this study was to determine the protein quality of lupin (Lupinus albus and Lupinus angustifolius) and to determine their chemical composition, including dietary fiber.
Márcia Regina Pereira Monteiro, Aline Bárbara Pereira Costa, Suellen Fabiane Campos, Mauro Ramalho Silva, Cassiano Oliveira da Silva, Hércia Stampini Duarte Martino, Marialice Pinto Coelho Silvestre   +6 more
doaj  

Bioavailability comparison study of two benzathine benzylpenicillin 1,200,000 IU intramuscular formulations in healthy male participants under fast state

DST
Introduction: Benzathine benzylpenicillin G is a drug present in the list of essential medicines of the World Health Organization and largely used in Brazil, where this antibiotic is used for treating pneumonias, pharyngitis, syphilis, and other ...
Vinicius Marcondes Rezende, Paulo Galvinas, Carlos Sverdloff, Camila Leles Guimaraes, Anne Silveira, Camila Aihara, Marcia Aparecida Antonio, Renata Di Sessa   +7 more
doaj   +1 more source

Assemblage of a semi-arid annual plant community: abiotic and biotic filters act hierarchically.

PLoS ONE, 2012
The study of species coexistence and community assembly has been a hot topic in ecology for decades. Disentangling the hierarchical role of abiotic and biotic filters is crucial to understand community assembly processes.
Arantzazu L Luzuriaga, Ana M Sánchez, Fernando T Maestre, Adrián Escudero   +3 more
doaj   +1 more source

Effect of tillage and residue retention on maize productivity [PDF]

, 2011
In Bangladesh, maize is generally sown after extensive tilth and minimum residue retention. Conservation agriculture (CA) systems reduce the input costs, machinery use, CO2 emissions; and improve soil health (Raper et al., 1994).
Bell, R.W., Haque, M.E., Hossain, M.M., Islam, A.K.M.S., Karmaker, B., Rahman, M.A., Saleque, M.A.   +6 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Biological availability of digoxin. [PDF]

BMJ, 1973
J, Hamer, D, Chamberlain
openaire   +4 more sources

MEMOFinder: combining _de_ _novo_ motif prediction methods with a database of known motifs [PDF]

, 2008
*Background:* Methods for finding overrepresented sequence motifs are useful in several key areas of computational biology. They aim at detecting very weak signals responsible for biological processes requiring robust sequence identification like ...
Bartek Wilczynski, Jerzy Tiuryn, Milosz Darzynkiewicz   +2 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source