Results 141 to 150 of about 5,256,148 (309)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1930
Annual report of the Marine Biological Laboratory in Woods Hole. 1930.
Marine Biological Laboratory (Woods Hole MA)
core
Fluoride Release from Children's Toothpastes as an Indicator of Bioavailability
Objective: To evaluate the fluoride release from Colgate Zero Kids® dentifrice compared to two children’s dentifrices, Tandy® and Sorriso Kids®. Material and Methods: All products, from the same manufacturer, had identical fluoride formulations (NaF ...
Amanda Luisa Rodrigues de Paiva +5 more
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1921
Annual report of the Marine Biological Laboratory in Woods Hole. 1921.
Marine Biological Laboratory (Woods Hole MA)
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1965
Annual report of the Marine Biological Laboratory in Woods Hole. 1965.
Marine Biological Laboratory (Woods Hole MA)
core
Biological availability of phosphorus
In September 1978 the Engineering and Technological Aspects (ETA) Committee expressed its concerns to the Great Lakes Science Advisory Board that efforts to control inputs of pollutants to the Great Lakes, such as heavy metals and, in particular, phosphorus, were not directed at biologically available forms, but rather at the total inputs of the ...
openaire +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1944
Annual report of the Marine Biological Laboratory in Woods Hole. 1944.
Marine Biological Laboratory (Woods Hole MA)
core

