Results 161 to 170 of about 1,755,454 (302)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Complete Genome Sequence of Laguna Mountains Skipper (<i>Pyrgus ruralis lagunae</i>). [PDF]

Biodivers Genomes
Sprute M, Pirro S, Koepfli K, Longcore T, Osborne KH, Wilson T, Howorth P, Johnson J.   +7 more
europepmc   +1 more source

Soil P availability limits legume persistence and distribution in the fynbos of the Cape Floristic Region

, 2010
Includes abstract.Includes bibliographical references (leaves 64-83).Legumes are unable to persist through post-fire succession in fynbos vegetation of the CFR unlike species in families such as Proteaceae and Restionaceae. The majority of fynbos legumes
Power, Simon C
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Advancing Wheat Productivity Through Nutrient Interactions, Fertilizer Practices, and Genetic Improvement. [PDF]

Life (Basel)
Elbasyoni IS, Al-Otayk SM, Ghonimy M, Motawei MI.   +3 more
europepmc   +1 more source

Characterization of PAH-contaminated soils focusing on availability, chemical composition and biological effects

, 2006
The risks associated with a soil contaminated by polycyclic aromatic hydrocarbons (PAHs) are generally assessed by measuring individual PAHs in the soil and correlating the obtained amounts to known adverse biological effects of the PAHs. The validity of
Bergknut, Magnus
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Amino Acid-Fatty Acid Profile as a Novel Predictive Method in the Assessment of Diagnosis and Treatment Efficacy of Anxiety-Related Disorders and Mood Disorders. [PDF]

Int J Mol Sci
Kowalczyk M, Aebisher D, Szpara J, Czech S, Kowalczyk E, Majsterek I, Bartusik-Aebisher D, Henrykowska G.   +7 more
europepmc   +1 more source

The effect of stage of maturity on the biological availability of magnesium from wheat and orchardgrass fed to sheep

, 2012
Wheat, a tetany prone forage, and orchardgrass, a non-tetany prone forage, were cut at three stages of maturity to determine the magnesium availability in these forages for lambs.
Stager, Cynthia Lee
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source