Results 171 to 180 of about 2,832,681 (326)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Correction: Plant factories are heating up: hunting for the best combination of light intensity, air temperature and root-zone temperature in lettuce production. [PDF]

Front Plant Sci
Carotti L, Graamans L, Puksic F, Butturini M, Meinen E, Heuvelink E, Stanghellini C.   +6 more
europepmc   +1 more source

Biological Availability of Manganese Sources and Effects of High Dietary Manganese on Tissue Mineral Composition of Broiler-Type Chicks [PDF]

, 1984
J. Roy Black, C. B. Ammerman, P. R. Henry, R.D. MILES   +3 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Availability, price and affordability of anticancer medicines in Jiangsu Province, China: a cross-sectional survey study. [PDF]

Front Public Health
Yao Y, Zhu Y, Jing Z, Gao L, Zhu H, Wang J, Wang S, Cao Z, Tao T, Li X.   +9 more
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Design, Synthesisand Biological Evaluation of Novel,Potent, Selective and Orally Available DGKα Inhibitors for theTreatment of Tumors

Hongfu Lu (1422337), Sujing Shi (21493493), Huaxing Yu (6598679), Deheng Sun (2543986), Haoyu Zhang (1783690), Hui Cui (285760), Xin Cai (140935), Xiao Ding (273868), Shan Chen (232477), Man Zhang (466843), Jinxin Liu (311455), Ryan Shi (22750789), Alex Aliper (5044139), Feng Ren (304733), Alex Zhavoronkov (347712)   +14 more
openalex   +1 more source

Iron speciation and its biological availability in seawater: A workshop

, 1995
Mark L. Wells, Kenneth W. Bruland
openalex   +2 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

The Effect of Adding Spent Mushroom, Biofertilizers and Mineral Fertilizers on the Availability of Some Nutrients And The Soil Aggregates Stability

Maǧallaẗ al-baṣraẗ al-ʻulūm al-zirāʻiyyaẗ
This field experiment was carried out to study the Spent Mushroom farm wastes, biological and mineral fertilizers and their effect on the availability of soil nutrients and soil aggregate in a field planted with Zea mays L. measurements were taken at two-
Hudah T. Al-Hrkane, Iman Q. Mohammed, Luma S. J. Al-Taweel   +2 more
doaj   +2 more sources