Results 261 to 270 of about 9,777,305 (324)

Cholinergic network modulation in disinhibited eating behavior. [PDF]

Commun Biol
Hesse S, Rullmann M, Günnewig T, Schweickert de Palma E, Burmeister L, van Grinsven M, Zientek F, Luthardt J, Hankir MK, Meyer PM, Becker GA, Patt M, Brust P, Pleger B, Stumvoll M, Hilbert A, Blüher M, Sabri O.   +17 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

<i>NOTCH1</i> Mutation Is Associated With Response to Bruton Tyrosine Kinase Inhibitors in Chronic Lymphocytic Leukemia: A Retrospective Study. [PDF]

EJHaem
Haméon C, Houot R, Gyan E, Vallet N, Lachot S, Ganard M, Herault O, De Guibert S, Pastoret C, Dartigeas C.   +9 more
europepmc   +1 more source

Organ-specific transcriptional and metabolic adaptations of potato plants to limited phosphate availability prior and after tuberization. [PDF]

Plant J
Nasr Esfahani M, Koch L, Hofmann J, Sonnewald S, Sonnewald U.   +4 more
europepmc   +1 more source

An early origin of oxygenic photosynthesis delays the Great Oxidation. [PDF]

Philos Trans R Soc Lond B Biol Sci
Horne JE, Goldblatt C, Kump L.
europepmc   +1 more source

Cataloguing and evaluating Irish health data resources for primary care cancer research. [PDF]

BJC Rep
Brady Bates O, Carroll A, Hughes C, Murtagh C, Jacob B, Bennett K, Redmond P.   +6 more
europepmc   +1 more source

Identifying and mitigating the biological effectors of the social determinants of health in cancer. [PDF]

J Natl Cancer Inst
Wagner M, Benson CL, Obeng-Gyasi S, Conzen S, Mccullough LE, Halbert CH, Gerson SL.   +6 more
europepmc   +1 more source

Manganese-modulated proteome and phosphoproteome dataset in the opportunistic yeast <i>Candida albicans</i>. [PDF]

Data Brief
Henry M, Woods M, Gutierrez-Gongora D, Geddes-McAlister J, Sellam A.   +4 more
europepmc   +1 more source

OpTiles: An R Package for Adaptive Tiling and Methylation Variability Profiling

Migliaccio G, Möbus L, del Giudice G, Morikka J, Federico A, Serra A, Greco D.   +6 more
europepmc   +1 more source