Results 191 to 200 of about 261,145 (320)

Light at night disrupts biological clocks, calendars, and immune function [PDF]

, 2021
William H. Walker, Jacob R. Bumgarner, Darius D. Becker‐Krail, Laura E. May, Jennifer A. Liu, Randy J. Nelson   +5 more
openalex   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

The biological clock enhancer nobiletin ameliorates steatosis in genetically obese mice by restoring aberrant hepatic circadian rhythm.

Am J Physiol Gastrointest Liver Physiol, 2022
Larion S, Padgett CA, Butcher JT, Mintz JD, Fulton DJ, Stepp DW.   +5 more
europepmc   +1 more source

Micro RNAs and the biological clock: a target for diseases associated with a loss of circadian regulation. [PDF]

Afr Health Sci, 2020
Ma Q, Mo G, Tan Y.
europepmc   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

The human biological clock and aging-a comprehensive approach integrating reductionism, holism, and geromedicine for proactive healthspan strategies. [PDF]

Front Aging
Phua TJ.
europepmc   +1 more source

Small Molecules Targeting Biological Clock; A Novel Prospective for Anti-Cancer Drugs. [PDF]

Molecules, 2020
Rahman S, Wittine K, Sedić M, Markova-Car EP.   +3 more
europepmc   +1 more source

Weather and Seasons Together Demand Complex Biological Clocks [PDF]

, 2009
Carl Troein, James Locke, Matthew S. Turner, Andrew J. Millar   +3 more
openalex   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Optimization of main components of artificial compound feed (ACF) for Hippocampus kuda based on the synergistic expression of biological clock genes. [PDF]

Fish Physiol Biochem
Xu Y, Yang B, Jinyang X, Lou Y.
europepmc   +1 more source