Results 211 to 220 of about 3,185,463 (348)

Teaching the Biological Clock: Age-Related Fertility Decline and Sex Education

, 2014
Kerry Lynn Macintosh
openalex   +1 more source

Bayesian neural networks for the optimisation of biological clocks in humans [PDF]

, 2020
Gerardo Alfonso, Juan R. González
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Circadian rhythms revealed: unraveling the genetic, physiological, and behavioral tapestry of the human biological clock and rhythms. [PDF]

Front Sleep
Morin R, Forest G, Imbeault P.
europepmc   +1 more source

The biological clock enhancer nobiletin ameliorates steatosis in genetically obese mice by restoring aberrant hepatic circadian rhythm.

Am J Physiol Gastrointest Liver Physiol, 2022
Larion S, Padgett CA, Butcher JT, Mintz JD, Fulton DJ, Stepp DW.   +5 more
europepmc   +1 more source

Micro RNAs and the biological clock: a target for diseases associated with a loss of circadian regulation. [PDF]

Afr Health Sci, 2020
Ma Q, Mo G, Tan Y.
europepmc   +1 more source

Freezing the biological clock: demographics of an oocyte cryopreservation program [PDF]

, 2008
J.M. Knopman, Andrea Reh, N. Noyes, J. Grifo, L.C. Krey, Lisa Kump   +5 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Clock genes and biological rhythms. Effects of psychotropic drugs [PDF]

, 2012
Teresa Maria Osland
openalex  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source