Results 31 to 40 of about 261,145 (320)

The role of circadian clock in astrocytes: From cellular functions to ischemic stroke therapeutic targets

open access: yesFrontiers in Neuroscience, 2022
Accumulating evidence suggests that astrocytes, the abundant cell type in the central nervous system (CNS), play a critical role in maintaining the immune response after cerebral infarction, regulating the blood-brain barrier (BBB), providing nutrients ...
Yuxing Zhang   +11 more
doaj   +1 more source

Prokineticin 2 Is a Target Gene of Proneural Basic Helix-Loop-Helix Factors for Olfactory Bulb Neurogenesis [PDF]

open access: yes, 2007
Prokineticin 2, a cysteine-rich secreted protein, regulates diverse biological functions including the neurogenesis of olfactory bulb. Here we show that the PK2 gene is a functional target gene of proneural basic helix-loop-helix (bHLH) factors ...
Anderson, David J.   +6 more
core   +1 more source

Computing with biological switches and clocks [PDF]

open access: yesNatural Computing, 2018
The complex dynamics of biological systems is primarily driven by molecular interactions that underpin the regulatory networks of cells. These networks typically contain positive and negative feedback loops, which are responsible for switch-like and oscillatory dynamics, respectively.
Andrew Phillips   +8 more
openaire   +5 more sources

Ketogenic diet induces expression of the muscle circadian gene Slc25a25 via neural pathway that might be involved in muscle thermogenesis

open access: yesScientific Reports, 2017
We recently found that the mRNA expression of Slc25a25, a Ca2+-sensitive ATP carrier in the inner mitochondrial membrane, fluctuates in a circadian manner in mouse skeletal muscle.
Reiko Nakao   +2 more
doaj   +1 more source

Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]

open access: yes, 2017
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core   +2 more sources

Research progress of biological clock in regulation of tumor development [PDF]

open access: yesJichu yixue yu linchuang, 2020
Biological clock is a physiological controlling system with self-regulating functions. There is a close relationship between biological clock disorders and the occurrence of tumors, but underlying mechanism has not yet been elucidated.
GAO Dong-xiao, LIU Dan, GUO Qiang, LUO Ying, LIU Jing
doaj  

Light and circadian regulation of clock components aids flexible responses to environmental signals [PDF]

open access: yes, 2014
The circadian clock measures time across a 24h period, increasing fitness by phasing biological processes to the most appropriate time of day. The interlocking feedback loop mechanism of the clock is conserved across species; however, the number of loops
Akman, Ozgur E   +5 more
core   +2 more sources

Role of circadian gene Clock during differentiation of mouse pluripotent stem cells

open access: yesProtein & Cell, 2016
Biological rhythms controlled by the circadian clock are absent in embryonic stem cells (ESCs). However, they start to develop during the differentiation of pluripotent ESCs to downstream cells.
Chao Lu   +7 more
doaj   +1 more source

CLOCK inhibits the proliferation of porcine ovarian granulosa cells by targeting ASB9

open access: yesJournal of Animal Science and Biotechnology, 2023
Background Clock circadian regulator (CLOCK) is a core factor of the mammalian biological clock system in regulating female fertility and ovarian physiology.
Liang Huang   +9 more
doaj   +1 more source

Effects of LED spectrum on circadian rhythmic expression of clock genes and Aanat2 in the brain of juvenile European seabass (Dicentrarchus labrax)

open access: yesFrontiers in Marine Science, 2023
The circadian rhythm is a physiological phenomenon that occurs in various organisms with a cycle of about 24 hours. Light is one of the important environmental factors affecting biological rhythm.
He Ma   +14 more
doaj   +1 more source

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