Results 41 to 50 of about 261,145 (320)

Circadian clocks in health and disease: Dissecting the roles of the biological pacemaker in cancer [version 2; peer review: 2 approved]

open access: yesF1000Research, 2023
In modern society, there is a growing population affected by circadian clock disruption through night shift work, artificial light-at-night exposure, and erratic eating patterns.
Rachel C. Fellows   +4 more
doaj   +1 more source

FLOWERING LOCUS C -dependent and -independent regulation of the circadian clock by the autonomous and vernalization pathways [PDF]

open access: yes, 2006
Background The circadian system drives pervasive biological rhythms in plants. Circadian clocks integrate endogenous timing information with environmental signals, in order to match rhythmic outputs to the local day/night cycle.
Amasino, Richard M.   +5 more
core   +4 more sources

Role of PPARα in the Control of Torpor through FGF21-NPY Pathway: From Circadian Clock to Seasonal Change in Mammals

open access: yesPPAR Research, 2009
In nature, hibernating animals encounter fasting, cold temperature and short day seasonally. Torpor is a state of decreased physiological activity in an animal, usually characterized by a reduced body temperature and rate of metabolism to adapt such a ...
Norio Ishida
doaj   +1 more source

A Targeted Epigenetic Clock for the Prediction of Biological Age

open access: yesCells, 2022
Epigenetic clocks were initially developed to track chronological age, but accumulating evidence indicates that they can also predict biological age.
Noémie Gensous   +17 more
doaj   +1 more source

Dynamic Influence Networks for Rule-based Models [PDF]

open access: yes, 2017
We introduce the Dynamic Influence Network (DIN), a novel visual analytics technique for representing and analyzing rule-based models of protein-protein interaction networks.
Boutillier, Pierre   +6 more
core   +4 more sources

Evaluation of pediatric epigenetic clocks across multiple tissues

open access: yesClinical Epigenetics, 2023
Background Epigenetic clocks are promising tools for assessing biological age. We assessed the accuracy of pediatric epigenetic clocks in gestational and chronological age determination.
Fang Fang   +28 more
doaj   +1 more source

Rhythms of Locomotion Expressed by Limulus polyphemus, the American Horseshoe Crab: II. Relationship to Circadian Rhythms of Visual Sensitivity [PDF]

open access: yes, 2008
In the laboratory, horseshoe crabs express a circadian rhythm of visual sensitivity as well as daily and circatidal rhythms of locomotion. The major goal of this investigation was to determine whether the circadian clock underlying changes in visual ...
Bedford, Lisa   +2 more
core   +3 more sources

Identification of the Molecular Clockwork of the Oyster Crassostrea gigas. [PDF]

open access: yesPLoS ONE, 2017
Molecular clock system constitutes the origin of biological rhythms that allow organisms to anticipate cyclic environmental changes and adapt their behavior and physiology.
Mickael Perrigault, Damien Tran
doaj   +1 more source

A Biological Clock in Drosophila

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1985
The per locus plays a central role in the organization and function of the Drosophila biological clock. The gene has been mapped to a 7-kb DNA segment by physically locating the breakpoints of several chromosomal rearrangements that disrupt per function. This DNA contains a single transcription unit which produces a 4.5-kb poly(A)+ RNA.
F.R. Jackson   +3 more
openaire   +3 more sources

Biological clocks in theory and experiments [PDF]

open access: yesBMC Bioinformatics, 2005
Eukaryotes and some prokaryotes have adapted to the 24 h day/night cycle by evolving circadian clocks. The circadian clock now controls 24-hour rhythms in very many aspects of metabolism, physiology and behaviour. Day-length (photoperiod) measurement depends on the circadian clock, so the 24 h clock mechanism also governs seasonal rhythms, such as ...
Andrew J. Millar, Andrew J. Millar
openaire   +4 more sources

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