Results 41 to 50 of about 3,185,463 (348)

Cinnamic acid shortens the period of the circadian clock in mice

Biochemistry and Biophysics Reports, 2017
Cinnamic acid (CA) derivatives have recently received focus due to their anticancer, antioxidant, and antidiabetic properties. The present study aimed to determine the effects of cinnamic acid on the circadian clock, which is a cell-autonomous endogenous
Katsutaka Oishi, Saori Yamamoto, Hideaki Oike, Naoki Ohkura, Masahiko Taniguchi   +4 more
doaj   +1 more source

Watching the hands of the Arabidopsis biological clock [PDF]

, 2001
Oligonucleotide and cDNA microarrays have been used to analyse the mRNA levels of 8,000 genes in Arabidopsis thaliana throughout the day/night cycle. Genes involved in signal transduction and in various metabolic pathways were found to be coordinately ...
Davis, Seth J., Millar, A. J. (Andrew J.)   +1 more
core   +3 more sources

Maternal feeding controls fetal biological clock. [PDF]

PLoS ONE, 2008
BACKGROUND: It is widely accepted that circadian physiological rhythms of the fetus are affected by oscillators in the maternal brain that are coupled to the environmental light-dark (LD) cycle.
Hidenobu Ohta, Shanhai Xu, Takahiro Moriya, Masayuki Iigo, Tatsuya Watanabe, Norimichi Nakahata, Hiroshi Chisaka, Takushi Hanita, Tadashi Matsuda, Toshihiro Ohura, Yoshitaka Kimura, Nobuo Yaegashi, Shigeru Tsuchiya, Hajime Tei, Kunihiro Okamura   +14 more
doaj   +1 more source

The role of circadian clock in astrocytes: From cellular functions to ischemic stroke therapeutic targets

Frontiers in Neuroscience, 2022
Accumulating evidence suggests that astrocytes, the abundant cell type in the central nervous system (CNS), play a critical role in maintaining the immune response after cerebral infarction, regulating the blood-brain barrier (BBB), providing nutrients ...
Yuxing Zhang, Yuxing Zhang, Xin Zhao, Ying Zhang, Ying Zhang, Fukang Zeng, Fukang Zeng, Siyang Yan, Yao Chen, Zhong Li, Desheng Zhou, Lijuan Liu   +11 more
doaj   +1 more source

Muscle Bmal1 is Dispensable for the Progress of Neurogenic Muscle Atrophy in Mice

Journal of Circadian Rhythms, 2016
Global deletion of aryl hydrocarbon receptor nuclear translocator-like ('Arntl'; also known as 'Bmal1'), a molecular component of the circadian clock, resulted in an extreme loss of muscle mass.
Reiko Nakao, Shigeki Shimba, Katsutaka Oishi   +2 more
doaj   +1 more source

(-)-Epigallocatechin-3-gallate Ameliorates Intervertebral Disc Degeneration Through Reprogramming of the Circadian Clock

Frontiers in Pharmacology, 2021
The circadian clock is vital in the management of our daily physiological as well as metabolic processes. Disturbances of the clock can cause degenerative and age-related diseases.
Liangwei Mei, Yi Zheng, Teng Ma, Bing Xia, Xue Gao, Yiming Hao, Zhuojing Luo, Jinghui Huang   +7 more
doaj   +1 more source

The biological clock: Future of neurological disorders therapy.

Neural Regen Res, 2018
Dear editors, The seminal, discoveries by Jeffrey Connor Hall, Michael Rosbash and Michael Warren Young have earned the Nobel Prize in Physiology and Medicine 2017 for revealing a crucial physiological mechanism explaining biological clock, with ...
Gaikwad S.
europepmc   +2 more sources

Prokineticin 2 Is a Target Gene of Proneural Basic Helix-Loop-Helix Factors for Olfactory Bulb Neurogenesis [PDF]

, 2007
Prokineticin 2, a cysteine-rich secreted protein, regulates diverse biological functions including the neurogenesis of olfactory bulb. Here we show that the PK2 gene is a functional target gene of proneural basic helix-loop-helix (bHLH) factors ...
Anderson, David J., He, Fei, Li, Jia-Da, Ng, Kwan L., Sun, Yi E., Zhang, Chengkang, Zhou, Qun-Yong   +6 more
core   +1 more source

Ketogenic diet induces expression of the muscle circadian gene Slc25a25 via neural pathway that might be involved in muscle thermogenesis

Scientific Reports, 2017
We recently found that the mRNA expression of Slc25a25, a Ca2+-sensitive ATP carrier in the inner mitochondrial membrane, fluctuates in a circadian manner in mouse skeletal muscle.
Reiko Nakao, Shigeki Shimba, Katsutaka Oishi   +2 more
doaj   +1 more source

Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]

, 2017
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core   +2 more sources