Results 141 to 150 of about 11,395,252 (264)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1980
, 1981 Annual report of the Marine Biological Laboratory in Woods Hole. 1980.
Marine Biological Laboratory (Woods Hole MA)
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1939
, 1940 Annual report of the Marine Biological Laboratory in Woods Hole. 1939.
Marine Biological Laboratory (Woods Hole MA)
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1984
, 1985 Annual report of the Marine Biological Laboratory in Woods Hole. 1984.
Marine Biological Laboratory (Woods Hole MA)
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1981
, 1982 Annual report of the Marine Biological Laboratory in Woods Hole. 1981.
Marine Biological Laboratory (Woods Hole MA)
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1991
, 1992 Annual report of the Marine Biological Laboratory in Woods Hole. 1991.
Marine Biological Laboratory (Woods Hole MA)
core