Results 131 to 140 of about 2,950,696 (309)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The response of fungal community on citrus fruit surface to the application of Metschnikowia citriensis

Biological Control
Metschnikowia citriensis is an antagonistic yeast that was isolated from citrus systems, effectively controls postharvest green mold, blue mold, and sour rot in citrus fruits. This study explored its biocontrol mechanisms by treating citrus fruits with 1 
Hongyan Zhang, Shupei Wang, Lanhua Yi, Jian Ming, Kaifang Zeng   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

High temperatures will likely limit establishment success of the Brazilian peppertree thrips, Pseudophilothrips ichini (Thysanoptera: Phlaeothripidae) in the USA, despite variation in microhabitat thermal environments

Biological Control
Biological control of the invasive tree, Schinus terebinthifolia Raddi, is under investigation to improve conservation and restoration of native plant communities in the continental USA.
Nathan Harms, Megann Harlow, Ian Knight, Aaron Schad   +3 more
doaj   +1 more source

The potential of native parasitoids for the control of Mexican bean beetles: A genetic and ecological approach

, 2008
Bruchid beetles in the genus Zabrotes are important pests of field and stored beans all around the world and cause enormous economical losses in Mexico and Central America.
Aebi, Alexandre, Shani, Tal, Benrey, Betty, Hansson, Christer, Contreras-Garduno, Jorge, Mansion, Guilhem, Hansson, Christer,   +6 more
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Controlling Riptortus pedestris (Hemiptera: Alydidae) using Ooencyrtus utetheisae (Hymenoptera: Encyrtidae)

Biological Control
Riptortus pedestris (Hemiptera: Alydidae) is an important pest that affects soybean cultivation in East Asia. In the present study, the ability of Ooencyrtus utetheisae (Hymenoptera: Encyrtidae) to provide biological control of R. pedestris was evaluated
Tianjie Liu, Yue Cui, Yichang Xing, Yu Gao, Yuan Chen, Shusen Shi, Jinping Zhang   +6 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Effects of tomato treatments with commercial formulations of entomopathogenic fungi on the pest Tuta absoluta and the predator Macrolophus pygmaeus

Biological Control
Tuta absoluta is a devasting pest causing severe yield losses in most tomato-growing areas. Macrolophus pygmaeus is a generalist predator released in tomato crop to control T. absoluta.
Sara Scovero, Silvia T. Moraglio, Luciana Tavella   +2 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source