Results 111 to 120 of about 5,464,709 (296)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Host-associated cues and their effects on the jumping behavior of Steinernema siamkayai

Biological Control
Entomopathogenic nematodes are insect parasites with infective juveniles (IJs) employing host-seeking behaviors from ambush to cruise foraging. In ambush-foraging species, IJs often exhibit jumping behavior for attachment to host insects.
Puping Ta-oun, Toyoshi Yoshiga
doaj   +1 more source

Prioritising targets for biological control of weeds - a decision support tool for policy makers [PDF]

This report outlines a framework of the overall process of prioritising targets for biological control and includes a decision support tool that enables policy makers to determine whether biological control is a suitable option for a proposed target ...
Bertie Hennecke, Jose ten Have, Lucy Arrowsmith   +2 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Climatic suitability and potential distribution of earleaf acacia and its candidate biological control agent Trichilogaster sp

Biological Control
Acacia auriculiformis A. Cunn. ex Benth. (Fabaceae), commonly known as earleaf acacia (ELA), is an invasive evergreen tree introduced to the USA from its native subtropical forests in Australia, Papua New Guinea, and Indonesia.
Sara S. MacDonald, Emily J. Le Falchier, Lindsay P. Campbell, Ryan Zonneveld, Carey R. Minteer   +4 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Biological control sought for ash whitefly

California Agriculture, 1990
Ash whitefly has spread over a large portion of California since the initial infestation was discovered in Los Angeles County in 1988. Populations have grown to high densities on a wide range of host plants, including ash, pear, apple, citrus, and other ...
T Bellows, T Paine, K Arakawa, C Meisenbacher, P Leddy, J Kabashima   +5 more
doaj  

Soybean domestication and lead stress on plant–herbivore–parasitoid interactions

Biological Control
Plant domestication and soil heavy metal pollution alter plant–insect interactions and influence bottom-up and top-down effects. However, their combined effect on plants, herbivores, and parasitoids remains unclear.
Yating Liu, Luhan Li, Shangyang Li, Jiahao Xu, Zhaoyi Feng, Zhe Wang, Liya Zeng, Xiaohong Li   +7 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Biological control: Pitting insects against insects

California Agriculture, 1977
Biological control involves discovering, importing, and using the most effective natural enemies of pest insects or weeds that can be found. More than 10 million natural enemies of many kinds are released each year by the University of California (UC ...
R Boardman
doaj